Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Scientists identify potential target for treating cardiac fibrosis

A research team led by scientists from the Consortium for Fibrosis Research & Translation at the University of Colorado School of Medicine has identified a potential target for treating heart failure related to fibrosis.

17 Sep 2019

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings.

From Johns Hopkins Medicine 13 Sep 2019

Scientists use CAR-T cells to reverse cardiac fibrosis

Scientists have used CAR-T cell therapy to treat cardiac fibrosis, a key part of heart disease and cardiac arrest.

12 Sep 2019

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

University of Colorado Boulder engineers and faculty from the Consortium for Fibrosis Research & Translation at the University of Colorado Anschutz Medical Campus have teamed up to develop biomaterial-based "mimics" of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery.

12 Sep 2019

CAR T-cell therapy may be viable treatment option for heart disease

CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease.

12 Sep 2019

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

By combing through the entire genetic sequences of a person with a lung scarring disease and 13 of the person’s relatives, Johns Hopkins Medicine researchers say they have found a coding error in a single gene that is likely responsible for a rare form of the disease and the abnormally short protective DNA caps on chromosomes long associated with it.

From Johns Hopkins Medicine 11 Sep 2019

Research shows link between genetic mutation and flu-related heart complications

People with severe flu sometimes develop life-threatening heart problems, even when their hearts have been previously healthy, but the reason for that has been poorly understood.

10 Sep 2019

Researchers explore how talk therapy can help cystic fibrosis patients with mental health problems

Drexel University researchers are exploring how Acceptance and Commitment Therapy, a type of talk therapy, delivered via telemedicine, may alleviate the anxiety and depression common among cystic fibrosis patients.

7 Sep 2019

FDA approves first drug to treat patients with rare lung condition

The U.S. Food and Drug Administration today approved Ofev (nintedanib) capsules to slow the rate of decline in pulmonary function in adults with interstitial lung disease associated with systemic sclerosis or scleroderma, called SSc-ILD. It is the first FDA-approved treatment for this rare lung condition.

7 Sep 2019

'Lab on a chip' technology may help find new treatments for NAFLD

Non-alcoholic fatty liver disease--the accumulation of liver fat in people who drink little or no alcohol--is increasingly common around the world, and in the United States, it affects between 30 and 40 percent of adults.

29 Aug 2019

Lungs feed deadly bacteria in cystic fibrosis

In cystic fibrosis, Pseudomonas aeruginosa is a much-feared pathogen. The bacterium easily colonizes the lungs of people with cystic fibrosis, leading to chronic infections that are almost impossible to eradicate and are ultimately fatal.

22 Aug 2019

Computer simulations may guide precise treatment of patients with persistent atrial fibrillation

Scientists at Johns Hopkins have successfully created personalized digital replicas of the upper chambers of the heart and used them to guide the precise treatment of patients suffering from persistent irregular heartbeats.

19 Aug 2019

Wearable sensors decode dynamic sweat composition

A new wearable skin sensor developed at the University of California in Berkeley may be very useful to help us understand how the body’s chemical composition changes in a host of situations. For instance, these small patch-like devices could detect the presence of issues like fatigue or dehydration.

19 Aug 2019

Scientists find a potent weapon against antibiotic resistance

Antibiotic resistance is a big threat to global health, and a growing number of infections are now becoming harder to treat. The usual treatments, like antibiotics used to treat them, becomes less effective. Now, a team of researchers may have found a potent weapon against antibiotic-resistant bacteria, which can help treat persistent infections.

15 Aug 2019

Powerful weapon discovered to fight antibiotic resistance in Staphylococcus aureus

Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more susceptible to some common antibiotics.

14 Aug 2019

Human apolipoprotein E promotes hepatitis B virus infection

Human apolipoprotein E (apoE) promotes hepatitis B virus (HBV) infection and production, according to a study published DATE in the open-access journal PLOS Pathogens by Luhua Qiao and Guangxiang (George) Luo of the University of Alabama at Birmingham School of Medicine.

From PLOS ONE 13 Aug 2019

Fibrosis News and Research

Further Reading

Scientists identify potential target for treating cardiac fibrosis

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Scientists use CAR-T cells to reverse cardiac fibrosis

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

CAR T-cell therapy may be viable treatment option for heart disease

Gene coding error likely responsible for rare form of inherited 'short telomere' disease

Research shows link between genetic mutation and flu-related heart complications

Researchers explore how talk therapy can help cystic fibrosis patients with mental health problems

FDA approves first drug to treat patients with rare lung condition

'Lab on a chip' technology may help find new treatments for NAFLD

Lungs feed deadly bacteria in cystic fibrosis

Computer simulations may guide precise treatment of patients with persistent atrial fibrillation

Wearable sensors decode dynamic sweat composition

Scientists find a potent weapon against antibiotic resistance

Powerful weapon discovered to fight antibiotic resistance in Staphylococcus aureus

Human apolipoprotein E promotes hepatitis B virus infection

Three new early-career investigators join federally funded precision medicine initiative

HistoIndex, ILBS launch Center of Excellence to enhance NASH diagnostics and clinical trials

Simple, minimally-invasive tool to study nasal airways of cystic fibrosis patients

UW Medicine achieves milestone of 1,000 lung transplants

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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