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Teen diagnosed with liver cancer explores genetic link to rare cancers

A father-daughter scientific collaboration that began after the daughter was diagnosed with a rare liver cancer has led to an important finding and could have broader implications for many other rare cancers. Their story is being published this week in a top tier journal, Science.

3 Mar 2014

FSU researchers link prenatal nicotine exposure to future ADHD

Prenatal exposure to nicotine could manifest as attention deficit hyperactivity disorder in children born a generation later, according to a new study by Florida State University College of Medicine researchers.

28 Feb 2014

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Scientists from the Helmholtz Zentrum München and the Technische Universität München have discovered how the viral DNA of the hepatitis B virus (HBV) can be degraded in the cell nucleus of liver cells, consequently allowing the virus to be eliminated.

24 Feb 2014

Non-coding RNAs linked to cancer and cancer survival

Several scientists, including one at Simon Fraser University, have made a discovery that strongly links a little understood molecule, which is similar to DNA, to cancer and cancer survival.

21 Feb 2014

Supercomputer dramatically accelerates genome analysis

Although the time and cost of sequencing an entire human genome has plummeted, analyzing the resulting three billion base pairs of genetic information from a single genome can take many months.

20 Feb 2014

Pediatric Cancer Genome Project identifies genetic alteration in brain tumor ependymoma

The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project has identified the most common genetic alteration ever reported in the brain tumor ependymoma and evidence that the alteration drives tumor development. The research appears February 19 as an advanced online publication in the scientific journal Nature.

20 Feb 2014

Matching the right tumor with the right drug

There are three common drugs for advanced ovarian cancer: paclitaxel, cyclophosphamide, and topotecan. Like a shell game, if you pick the right drug a patient is likely to respond. And, unfortunately, picking the wrong drug can lead to treatment failure. As reported in this month's issue of the journal PLoS ONE, a University of Colorado Cancer Center and University of Virginia study used a sophisticated model of ovarian cancer genetics to match the right tumor with the right drug. Patients who were matched in this way lived an average 21 months longer than patients who were not matched.

19 Feb 2014

Scientists develop mathematical method for classifying forms of glioblastoma

Scientists at The Wistar Institute have developed a mathematical method for classifying forms of glioblastoma, an aggressive and deadly type of brain cancer, through variations in the way these tumor cells "read" genes. Their system was capable of predicting the subclasses of glioblastoma tumors with 92 percent accuracy. With further testing, this system could enable physicians to accurately predict which forms of therapy would benefit their patients the most.

18 Feb 2014

Scientists take steps to identify genetic component to bipolar disorder

Scientists know there is a strong genetic component to bipolar disorder, but they have had an extremely difficult time identifying the genes that cause it. So, in an effort to better understand the illness's genetic causes, researchers at UCLA tried a new approach.

13 Feb 2014

Study shows benefit of double mastectomy in women with BRCA-related breast cancer

Women with BRCA-related breast cancer who have a double mastectomy are nearly 50 per cent less likely to die of breast cancer within 20 years of diagnosis compared to women who have a single mastectomy, according to a new study led by Women's College Hospital's Kelly Metcalfe.

12 Feb 2014

New study co-led by scientists sheds light on role of genes, blood lipid levels in cardiovascular health

New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type.

10 Feb 2014

Study identifies seven new genetic regions associated with type 2 diabetes

Seven new genetic regions associated with type 2 diabetes have been identified in the largest study to date of the genetic basis of the disease.

9 Feb 2014

Study points to molecular pathway to treat recurring, deadly malignancies

Analyzing the genomes of twin 3-year-old sisters – one healthy and one with aggressive leukemia – led an international team of researchers to identify a novel molecular target that could become a way to treat recurring and deadly malignancies.

9 Feb 2014

Researchers shed light on role of genes and blood lipid levels in cardiovascular health

New genetic evidence strengthens the case that one well-known type of cholesterol is a likely suspect in causing heart disease, but also casts further doubt on the causal role played by another type. The findings may guide the search for improved treatments for heart disease.

9 Feb 2014

Researchers identify protein that regulates how genetic information transcribed from DNA to mRNA

Molecular biologists from Indiana University are part of a team that has identified a protein that regulates the information present in a large number of messenger ribonucleic acid molecules that are important for carrying genetic information from DNA to protein synthesis.

7 Feb 2014

Poll shows only 35% of respondents likely to seek aggressive treatment to cancer

A national poll from the University of Utah's Huntsman Cancer Institute shows 34 percent of respondents would not seek genetic testing to predict their likelihood of developing a hereditary cancer - even if the cost of the testing was not an issue.

6 Feb 2014

Researchers develop cardiac tissue from human stem cells to find cures for heart diseases

When it comes to finding cures for heart disease, scientists at Icahn School of Medicine at Mount Sinai are working to their own beat. They may have developed a tissue model for the human heart that can bridge the gap between animal models and human clinical trial patients.

4 Feb 2014

Scientists develop tissue model for human heart

When it comes to finding cures for heart disease scientists are working to their own beat. That's because they may have finally developed a tissue model for the human heart that can bridge the gap between animal models and human patients.

31 Jan 2014

Psychosis risk factors have limited predictive power

Factors known to be linked to schizophrenia risk have little predictive power at either the individual or population level, report researchers.

24 Jan 2014

Research reveals new information about the genetic complexity underpinning schizophrenia

The Icahn School of Medicine at Mount Sinai today announced the publication of two papers in the journal Nature that reveal new information about the genetic complexity underpinning schizophrenia. These collaborative studies represent the largest exome sequencing efforts to date to elucidate this mental illness, and together found that the disorder is likely caused by far more rare genetic mutations than previously suspected.

23 Jan 2014

Genetic Information News and Research

Teen diagnosed with liver cancer explores genetic link to rare cancers

FSU researchers link prenatal nicotine exposure to future ADHD

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Non-coding RNAs linked to cancer and cancer survival

Supercomputer dramatically accelerates genome analysis

Pediatric Cancer Genome Project identifies genetic alteration in brain tumor ependymoma

Matching the right tumor with the right drug

Scientists develop mathematical method for classifying forms of glioblastoma

Scientists take steps to identify genetic component to bipolar disorder

Study shows benefit of double mastectomy in women with BRCA-related breast cancer

New study co-led by scientists sheds light on role of genes, blood lipid levels in cardiovascular health

Study identifies seven new genetic regions associated with type 2 diabetes

Study points to molecular pathway to treat recurring, deadly malignancies

Researchers shed light on role of genes and blood lipid levels in cardiovascular health

Researchers identify protein that regulates how genetic information transcribed from DNA to mRNA

Poll shows only 35% of respondents likely to seek aggressive treatment to cancer

Researchers develop cardiac tissue from human stem cells to find cures for heart diseases

Scientists develop tissue model for human heart

Psychosis risk factors have limited predictive power

Research reveals new information about the genetic complexity underpinning schizophrenia

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