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Rocket Pharma partners with Stanford University to advance FA and PKD gene therapy research

Rocket Pharmaceuticals, Inc., a leading U.S.-based multi-platform gene therapy company, and the Stanford University School of Medicine today announced a strategic collaboration to support the advancement of Fanconi Anemia and Pyruvate Kinase Deficiency gene therapy research.

17 May 2018

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

Revealing all the steps required to activate an enzyme called a protein kinase may identify new ways to target cancer, according to new University of Arizona-led research.

16 May 2018

New drug reduces symptoms of Rett syndrome in preclinical models

A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome in preclinical models.

14 May 2018

Protein researchers identify several new potential targets for cancer

In a new study based on mouse cells internationally leading protein researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.

14 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

Breast cancer drug can accelerate growth of tumors, shows research

The breast cancer drug lapatinib which is designed to shrink tumours can sometimes cause them to grow in the lab, according to a new study published in eLife.

2 May 2018

Study explains how colon cancer cells spread to the liver

Colorectal cancer is the third most common cancer worldwide and the third-leading cause of cancer-related deaths. The main cause of death in patients with colorectal cancer is liver metastasis, with nearly 70% of patients eventually developing a liver tumor.

25 Apr 2018

AYOXXA launches advanced low-volume beads-on-a-chip multiplex protein analysis system

AYOXXA Biosystems GmbH, an international biotechnology company, today announces the introduction of its advanced low-volume beads-on-a-chip multiplex protein analysis system. The LUNARIS™ system can be readily integrated into any laboratory routine and is optimized to provide easy-to-use, standardized workflow from sample to result.

20 Apr 2018

Experts propose new solutions to increase benefit, affordability of targeted cancer medicines

Spending on cancer drugs in the United States has nearly doubled in the past five years and continues to grow, imposing substantial financial burden on patients with cancer.

18 Apr 2018

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states - that is, to regress to an earlier stage of development - which can lead it to become resistant to treatment.

12 Apr 2018

Study provides systematic view of gene enhancer activity in diverse tumors

At the heart of any cancer diagnosis or treatment are cells. If one thinks of the cell components controlling gene activation as a Russian nesting-doll of gene regulatory layers, within those increasingly smaller tiers are short pieces of non-coding DNA called enhancers.

5 Apr 2018

Study reports impact of spaceflight on cardiovascular progenitor cell development and signaling

A new study of the effects of spaceflight on the development of heart cells identified changes in calcium signaling that could be used to develop stem cell-based therapies for cardiac repair.

3 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

First-of-its-kind cancer drug effective in 93% of pediatric patients

A first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern's Simmons Cancer Center announced.

30 Mar 2018

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

Salk Institute scientists, together with researchers from Switzerland's University of Basel and University Hospital Basel, discovered a protein called LHPP that acts as a molecular switch to turn off the uncontrolled growth of cells in liver cancer.

29 Mar 2018

SLU researchers turn off excruciating chemo pain in animal model

In a recent paper published in the journal Pain, Saint Louis University researchers describe their success in an animal model in turning off the excruciating pain that often accompanies a colorectal cancer drug.

26 Mar 2018

Researchers make key discovery about cellular pathway linked to myriad of diseases

Researchers from the University of Dundee and the Francis Crick Institute have made a significant discovery about a cellular pathway associated with developmental defects and a myriad of diseases ranging from alopecia to colorectal cancer.

22 Mar 2018

Researchers propose alternative treatment to target lymphoma signaling at its root

Non-Hodgkin lymphomas are cancers that affect white blood cells of the immune system called B-lymphocytes or B cells. Like cells in all cancers, the B cells begin to grow out of control, creating tumors in the lymph nodes, spleen or other tissues. In 2010 alone, it was estimated that non-Hodgkin lymphomas caused 210,000 deaths worldwide.

22 Mar 2018

Researchers prove link between common childhood cancer and inflammation

The team of María Domínguez, researcher for the Neuroscience Institute, joint venture of the Miguel Hernández University in Elche and the Spanish National Research Council, has managed to prove for the first time that an important factor in the development of acute pediatric lymphoblastic leukemia is inflammation.

22 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

Kinase News and Research

Rocket Pharma partners with Stanford University to advance FA and PKD gene therapy research

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

New drug reduces symptoms of Rett syndrome in preclinical models

Protein researchers identify several new potential targets for cancer

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Breast cancer drug can accelerate growth of tumors, shows research

Study explains how colon cancer cells spread to the liver

AYOXXA launches advanced low-volume beads-on-a-chip multiplex protein analysis system

Experts propose new solutions to increase benefit, affordability of targeted cancer medicines

UCLA scientists identify four subtypes of melanoma with different drug sensitivities

Study provides systematic view of gene enhancer activity in diverse tumors

Study reports impact of spaceflight on cardiovascular progenitor cell development and signaling

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

First-of-its-kind cancer drug effective in 93% of pediatric patients

Salk scientists discover protein that 'turns off' uncontrolled liver cancer growth

SLU researchers turn off excruciating chemo pain in animal model

Researchers make key discovery about cellular pathway linked to myriad of diseases

Researchers propose alternative treatment to target lymphoma signaling at its root

Researchers prove link between common childhood cancer and inflammation

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Measuring Drug-Target Residence Times with Biochemical Assays eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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