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Researchers report new signaling exchange that mediates normal mammary gland development

The human body develops most tissue types during fetal development, in a mother's uterus. Yet one only tissue develops after birth: the mammary gland.

18 May 2018

Rocket Pharma partners with Stanford University to advance FA and PKD gene therapy research

Rocket Pharmaceuticals, Inc., a leading U.S.-based multi-platform gene therapy company, and the Stanford University School of Medicine today announced a strategic collaboration to support the advancement of Fanconi Anemia and Pyruvate Kinase Deficiency gene therapy research.

17 May 2018

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

The youngest patients with the brain tumor medulloblastoma are among the most challenging because their rapidly developing brains limit treatment options.

17 May 2018

Mayo discovery could enable development of personalized ovarian, brain cancer treatments

Mayo Clinic researchers have discovered that a molecular communication pathway – thought to be defective in cancer – is a key player in determining the effectiveness of measles virus oncolytic cancer treatment in ovarian and aggressive brain cancers.

17 May 2018

Study: MRI fusion biopsy outperforms standard prostate biopsy

Researchers at the University of Cincinnati have found that MRI fusion biopsy--coupling MRI and ultrasound to visualize suspicious lesions in the prostate gland and targeting the biopsy to that particular area--outperformed standard prostate biopsy in patients with a prior negative prostate biopsy.

16 May 2018

KTU researchers are developing mathematical methods to diagnose breast cancer

The team of researchers at Kaunas University of Technology, Lithuania are developing mathematical methods which could help diagnose breast cancer.

15 May 2018

Invasive cancers that are born to be bad show detectable differences from harmless tumors

Do metastatic cancer tumors "break bad" or are they "born bad"? This question is an essential mystery in cancer early detection and treatment. Lacking a clear answer, patients are given the same aggressive therapies when small, abnormal clusters of cells are discovered early, even though they might well be harmless.

15 May 2018

New study aims to mitigate risks associated with treatment of multiple myeloma

In a 10-patient cohort study led by Dr. Jean Roy that aims to understand how to mitigate the risks associated with the treatment of multiple myeloma, a malignant cancer, researchers have adopted an innovative approach based on the unique immunological properties of umbilical cord blood in an effort to improve the safety and efficiency of allografting, the preferred treatment for this disease

11 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

New technology detects the 'glow' to guide brain tumor resection

Research by Barrow Neurological Institute physicians and University of Washington scientists on novel imaging technology for malignant brain tumors was published in the April issue of World Neurosurgery.

10 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

Centrosome amplification may contribute to initiation of cancers, research suggests

Cells begin to accumulate centrosomes - organelles that play a vital role during cell division - before they transform into cancer cells, according to a new study of patients with Barrett's esophagus condition, which is associated with esophageal cancer.

8 May 2018

Penn surgeons perform first ever robot-assisted complex spinal surgery for rare tumor removal

Noah Pernikoff is back to his life in New York City after becoming the first patient in the world to undergo a complex three-part, robotic-assisted surgery.

3 May 2018

New study evaluates expression of PD-L1 in human medulloblastoma

This study evaluated the expression of PD-L1 and markers of immune mediated resistance in human medulloblastoma, the most common malignant pediatric brain tumor.

3 May 2018

Nearly 50 people present with rare eye cancer - ocular melanoma

At least 50 people have been diagnosed with a rare type of eye cancer called ocular melanoma. They are all residents of two locations - Huntersville, North Carolina, and Auburn, Alabama. The cancer is rare and occurs in only six per 1 million population. The high rate of incidence of this cancer in these two locations has stumped researchers.

2 May 2018

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

According to a new study, the status of lymph nodes rather than the status of the primary tumor following preoperative neoadjuvant chemotherapy or chemoradiation therapy is the most important factor that determines whether patients with locally advanced esophageal cancer will survive.

2 May 2018

New pill for breast cancer diagnosis could do a better job than mammograms

As many as one in three women treated for breast cancer undergo unnecessary procedures, but a new method for diagnosing it could do a better job distinguishing between benign and aggressive tumors.

30 Apr 2018

More suspected cancer cases can be identified early within primary care

Considerably more cases of suspected cancer can today be identified early within primary care. Partly based on symptoms but also statistics on the patients' visits to health centers, indicates research from Sahlgrenska Academy at University of Gothenburg, Sweden.

27 Apr 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Malignant News and Research

Researchers report new signaling exchange that mediates normal mammary gland development

Rocket Pharma partners with Stanford University to advance FA and PKD gene therapy research

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

Mayo discovery could enable development of personalized ovarian, brain cancer treatments

Study: MRI fusion biopsy outperforms standard prostate biopsy

KTU researchers are developing mathematical methods to diagnose breast cancer

Invasive cancers that are born to be bad show detectable differences from harmless tumors

New study aims to mitigate risks associated with treatment of multiple myeloma

Researchers identify six genes that predispose carriers to develop medulloblastoma

New technology detects the 'glow' to guide brain tumor resection

New case study shows CAR T therapy as viable option for AML patients

Centrosome amplification may contribute to initiation of cancers, research suggests

Penn surgeons perform first ever robot-assisted complex spinal surgery for rare tumor removal

New study evaluates expression of PD-L1 in human medulloblastoma

Nearly 50 people present with rare eye cancer - ocular melanoma

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

New pill for breast cancer diagnosis could do a better job than mammograms

More suspected cancer cases can be identified early within primary care

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

Researchers target telomerase for killing NRAS-mutant melanoma cells

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