Opioids News and Research

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An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the beneficial effects and the side effects of opioids.

New lifesaving product aims at reducing death toll from heroin abuse

A new, lifesaving product aimed at reducing the death toll from heroin abuse — developed by a professor at the University of Kentucky College of Pharmacy — is in its final round of clinical trials and has received Fast Track designation by the Food and Drug Administration.

7 Aug 2014

New tool promises to reduce deaths caused by heroin overdose

A new, lifesaving product aimed at reducing the death toll from heroin abuse - developed by a professor at the University of Kentucky College of Pharmacy - is in its final round of clinical trials and has received Fast Track designation by the Food and Drug Administration.

7 Aug 2014

New study casts doubt on the effectiveness of brief counseling for illicit drug use

In an effort to stem substance use, the U.S. has invested heavily in the past decade in a brief screening-and-intervention protocol for alcohol and other drugs.

7 Aug 2014

FSMB takes effort to educate physicians on safe prescribing of opioid analgesics

The Federation of State Medical Boards (FSMB) announced today that the nation's state medical boards have kicked off a multi-state effort to educate health care professionals on the safe and responsible prescribing of extended-release (ER) and long-acting (LA) opioid analgesics for patients with chronic pain.

4 Aug 2014

Opioid use does not impair reverse shoulder arthroplasty success

Taking opioids prior to reverse shoulder arthroplasty does not hamper patients’ chances of having successful outcomes, researchers have found.

28 Jul 2014

Minister Ambrose calls for proposals to tackle prescription drug abuse

The Honourable Rona Ambrose, Minister of Health, today issued a national Call for Proposals to improve the prescribing practices for prescription drugs that have a high risk of abuse or addiction.

26 Jul 2014

FDA approves Targiniq ER to treat severe pain

Today, the U.S. Food and Drug Administration approved Targiniq ER (oxycodone hydrochloride and naloxone hydrochloride extended-release tablets), an extended-release/long-acting (ER/LA) opioid analgesic to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

24 Jul 2014

Telecare approach improves chronic musculoskeletal pain management

A collaborative care approach delivered by telephone is effective for managing chronic musculoskeletal pain, show findings from the Stepped Care to Optimize Pain Care Effectiveness study.

21 Jul 2014

Viewpoints: GOP's 'cynical' lawsuit against Obama; debt crisis is not over

There's not much that Republicans like about the 2010 Affordable Care Act, but one thing they particularly dislike is the requirement that employers with 50 or more full-time workers provide comprehensive health insurance.

18 Jul 2014

New study finds highest rates of decline in prescription drug misuse nationwide

Five states that have implemented multi-faceted prescription drug abuse prevention programs in recent years showed the highest rate of decline in prescription drug misuse rates nationwide, according to a new study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services.

From Quest Diagnostics 17 Jul 2014

Once-a-day pill for patients experiencing opioid-induced constipation

Opioids - strong morphine-based painkillers - are widely prescribed to patients experiencing chronic severe pain. While these drugs are very effective for treating and managing pain, they have one particularly bothersome side effect: constipation.

17 Jul 2014

Telecare intervention leads to improvement in chronic musculoskeletal pain

A telephone-delivered intervention, which included automated symptom monitoring, produced clinically meaningful improvements in chronic musculoskeletal pain compared to usual care, according to a study in the July 16 issue of JAMA.

16 Jul 2014

Pennsylvania releases statewide guidelines on use of prescription opioids for chronic non-cancer pain

On behalf of Governor Tom Corbett, the Pennsylvania Departments of Drug and Alcohol Programs and Health, in partnership with the Pennsylvania Medical Society, today released statewide guidelines to address the use of prescription opioids to treat chronic non-cancer pain.

11 Jul 2014

Kaleo announces U.S. availability of EVZIO for emergency treatment of opioid overdose

Kaleo, a privately-held pharmaceutical company headquartered in Richmond, Virginia, today announced the United States (U.S.) commercial availability of EVZIO for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression.

10 Jul 2014

State highlights: N.Y. legalizes medical marijuana; La. Medicaid paid for ineligible inmate care; Md. checking Medicaid rolls for unqualified

New York on Monday became the 23rd state to legalize certain forms of marijuana for medical reasons as Gov. Andrew Cuomo signed legislation into law at an event in Manhattan. The measure, which passed both houses of the legislature during the final moments of the legislative session, in June, is significantly more restrictive than other medical-marijuana laws in the nation (Orden, 7/7).

9 Jul 2014

State highlights: N.C. lawmakers reach Medicaid agreement; Idaho asks SCOTUS to take up Medicaid reimbursement

For the past few weeks, two big issues have kept the two chambers of the General Assembly from reaching an agreement on next year's state budget: teacher salaries and Medicaid. But on Wednesday, the Senate and the House of Representatives finally moved closer to agreement on their Medicaid forecasts, loosening a logjam that's kept legislators in Raleigh past July 1, the beginning of the fiscal year (Hoban, 7/3).

4 Jul 2014

Prescription drug deaths drop in Fla. after crackdown on doctors

Deaths involving narcotic painkillers dropped 26 percent over two years in Florida after stricter doctor scrutiny, according to a report from the federal Centers for Disease Control and Prevention.

2 Jul 2014

Targeting ASIC-related neurotransmission may lead to new therapies for treating drug addiction

University of Iowa researchers have discovered a new form of neurotransmission that influences the long-lasting memory created by addictive drugs, like cocaine and opioids, and the subsequent craving for these drugs of abuse. Loss of this type of neurotransmission creates changes in brains cells that resemble the changes caused by drug addiction.

28 Jun 2014

Trevena's Phase 1b data for TRV130 published in the journal Pain

Trevena, Inc., a clinical stage biopharmaceutical company and the leader in the discovery of G protein coupled receptor (GPCR) biased ligands, today announced the publication of its Phase 1b data for TRV130 in the journal Pain.

24 Jun 2014

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

BioLineRx Ltd., a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today it has in-licensed BL-1110, a novel compound for the treatment of neuropathic pain.

23 Jun 2014

Opioids News and Research

Further Reading

New lifesaving product aims at reducing death toll from heroin abuse

New tool promises to reduce deaths caused by heroin overdose

New study casts doubt on the effectiveness of brief counseling for illicit drug use

FSMB takes effort to educate physicians on safe prescribing of opioid analgesics

Opioid use does not impair reverse shoulder arthroplasty success

Minister Ambrose calls for proposals to tackle prescription drug abuse

FDA approves Targiniq ER to treat severe pain

Telecare approach improves chronic musculoskeletal pain management

Viewpoints: GOP's 'cynical' lawsuit against Obama; debt crisis is not over

New study finds highest rates of decline in prescription drug misuse nationwide

Once-a-day pill for patients experiencing opioid-induced constipation

Telecare intervention leads to improvement in chronic musculoskeletal pain

Pennsylvania releases statewide guidelines on use of prescription opioids for chronic non-cancer pain

Kaleo announces U.S. availability of EVZIO for emergency treatment of opioid overdose

State highlights: N.Y. legalizes medical marijuana; La. Medicaid paid for ineligible inmate care; Md. checking Medicaid rolls for unqualified

State highlights: N.C. lawmakers reach Medicaid agreement; Idaho asks SCOTUS to take up Medicaid reimbursement

Prescription drug deaths drop in Fla. after crackdown on doctors

Targeting ASIC-related neurotransmission may lead to new therapies for treating drug addiction

Trevena's Phase 1b data for TRV130 published in the journal Pain

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

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