Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

26 Jan 2022

SARS-CoV-2 infection found in wild white-tailed deer in Canada

In a recent study posted to the bioRxiv* preprint server, scientists investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in white-tailed deer (WTD) in southern Québec, Canada, as part of a more extensive pan-Canadian analysis into SARS-CoV-2 spillover into wildlife. To further define SARS-CoV-2 infection in this species, researchers used viral genomes and isolation.

25 Jan 2022

Growth advantage of SARS-CoV-2 Omicron variant found to be partly due to shorter serial interval

In a new study, a team of researchers assessed how serial intervals of SARS-CoV-2 Omicron and Delta variants varied during the same time period in the Netherlands.

25 Jan 2022

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

In a new study, researchers assessed the extent and duration of the neutralization of SARS-CoV-2 Omicron variant of concern after the administration of two and three doses of the BNT162b2 mRNA vaccine.

25 Jan 2022

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

A recent study evaluated the sensitivity and specificity of a “spit and mail” serology test.

25 Jan 2022

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Researchers from Portugal reported a 75% risk reduction in hospitalizations for individuals infected with Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the Delta variant and a shorter length of stay and lower mortality if hospitalization does occur. Their paper is currently available on the medRxiv* preprint server while undergoing peer review.

24 Jan 2022

Neurological complications of the SARS-CoV-2 vaccine

In a study published in the latest issue of the journal Neurological Sciences, a team of researchers described a three-patient case series presenting with neurological manifestations after the coronavirus disease 2019 (COVID-19) vaccination, followed by a literature review, to propose hypotheses on how neurological symptoms might develop after vaccination.

24 Jan 2022

Danish study shows lower risk of hospitalization in Omicron cases compared to Delta

In a recent study posted to the Preprints with The Lancet* server, a large team of researchers estimated the comparative risk of hospitalization after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron and Delta variants of concern (VOCs) in Denmark.

24 Jan 2022

The long-term neurologic consequences of COVID-19

A team of researchers recently provided insights into central nervous system consequences of the coronavirus disease 2019 (COVID-19) in a perspective paper published in the Science journal.

24 Jan 2022

New, low-cost COVID-19 test could make high-performance testing more accessible

Researchers at the University of Washington have developed a new test for COVID-19 that combines the speed of over-the-counter antigen tests with the accuracy of PCR tests that are processed in medical labs and hospitals.

24 Jan 2022

Impact of SARS-CoV-2 booster vaccination on Delta variant resurgence in Israel

In a new study, researchers constructed a discrete-time age-of-infection age-stratified transmission model to accurately determine the individual to population-level data on SARS-CoV-2 Delta surge dynamics in Israel

24 Jan 2022

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

A new study assessed the dynamics of IgG titers over 18 months in patients who had recovered from COVID-19 infections during March 2020.

24 Jan 2022

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

A new study revealed that the expression of HERV-W envelope protein (ENV) in lymphoid cells from COVID-19 patients correlated with disease outcome making them biomarkers of lymphocyte exhaustion.

24 Jan 2022

Novel SARS-CoV-2 mutations reported in chronic HIV patients

A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.

23 Jan 2022

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Researchers assess the impact of the SARS-CoV-2 Omicron variant of concern on symptoms of SARS-CoV-2 infection.

23 Jan 2022

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

The goal of the current study was to collect data on the prevalence of SARS-CoV-2 in bivalve mollusks harvested in the Campania region using dd RT-PCR for the detection of low levels of virus in mollusk tissues.

21 Jan 2022

A validated risk-stratification system to manage COVID-19 outpatients

A group of researchers developed a risk-stratification system from existing scoring methods that are exclusively for outpatients.

20 Jan 2022

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Researchers present evidence for early community transmission of the SARS-CoV-2 Omicron variant in New Delhi, India.

20 Jan 2022

Determining COVID-19 vaccine effectiveness among health care workers in Wales

A new study revealed an overall high vaccine uptake and significant vaccine effectiveness of BNT162b2 against COVID-19, among healthcare workers in Wales.

20 Jan 2022

Polymerase Chain Reaction News and Research

Further Reading

Cannabidiol inhibits SARS-CoV-2 replication in human cells and mice

SARS-CoV-2 infection found in wild white-tailed deer in Canada

Growth advantage of SARS-CoV-2 Omicron variant found to be partly due to shorter serial interval

Impact of a third BNT162b2 dose on SARS-CoV-2 Omicron variant

Sensitivity and specificity of a “spit and mail” SARS-CoV-2 serology test

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Neurological complications of the SARS-CoV-2 vaccine

Danish study shows lower risk of hospitalization in Omicron cases compared to Delta

The long-term neurologic consequences of COVID-19

New, low-cost COVID-19 test could make high-performance testing more accessible

Impact of SARS-CoV-2 booster vaccination on Delta variant resurgence in Israel

Antibody response 18 months after SARS-CoV-2 infection in vaccinated and unvaccinated individuals

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Human endogenous retrovirus type W envelope protein found to be a biomarker of COVID-19 severity

Novel SARS-CoV-2 mutations reported in chronic HIV patients

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

A validated risk-stratification system to manage COVID-19 outpatients

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Determining COVID-19 vaccine effectiveness among health care workers in Wales

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