Precision Medicine News and Research

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Study shows how melanomas assist T cells from identifying and killing tumor cells

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

17 Dec 2020

4E-BP proteins are key to unlock the antidepressant effect of ketamine in the brain

A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

17 Dec 2020

Oral hormone therapy significantly alters the metabolome of postmenopausal women

Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women.

16 Dec 2020

$3.7 million NIH grant supports development of biosensor technology for diagnosing viral diseases

For over ten years, Ali Yanik has been working to develop novel biosensor technology to provide rapid, low-cost testing for disease diagnostics and precision medicine.

16 Dec 2020

New tool aids in the discovery of RNA medicines for undruggable diseases

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some "undruggable" diseases, including a type of metastatic breast cancer.

15 Dec 2020

Researchers to investigate why exercise makes some people healthier than others

Why do some people benefit so much from exercise while others enjoy few health gains or even suffer harm? Does age matter when it comes to exercise's health benefits? Are there "molecular signatures" - sets of genes, proteins and other variables ¬- that reveal the answers?

11 Dec 2020

Skin may help to predict future heart problems

Our skin tells us when we've spent too much time in the sun or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin can also foretell issues unrelated to the protective barrier.

10 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Henry Ford Health System announces receipt of $16 million gift to Henry Ford Pancreatic Cancer Center

Henry Ford Health System today announced a $16 million gift to its Henry Ford Pancreatic Cancer Center, which was launched in 2018 by an initial $20 million gift from the same donor, who wishes to remain anonymous.

7 Dec 2020

Study finds surprising link between ALS, FTD and Huntington's disease-associated mutation

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington's disease.

5 Dec 2020

Breakthrough in microscopy, endoscopy may soon revolutionize the study of cellular origin of diseases

A breakthrough in microscopy and endoscopy will soon revolutionize the study of the cellular origin of diseases, advancing the field of precision medicine. This is the goal of CRIMSON, a trans-disciplinary and trans-national research project recently funded by European Commission.

2 Dec 2020

Deep learning model identifies imaging biomarkers to predict breast cancer risk in women

Researchers at Massachusetts General Hospital (MGH) have developed a deep learning model that identifies imaging biomarkers on screening mammograms to predict a patient's risk for developing breast cancer with greater accuracy than traditional risk assessment tools.

30 Nov 2020

World’s largest proteomics centre accelerates biomarker discoveries to improve people’s lives

Opened in 2016, Manchester’s Stoller Biomarker Discovery Centre (SBDC) is a globally renowned, multi-million-pound precision medicine research facility.

From Stoller Biomarker Discovery Centre 30 Nov 2020

Study finds how the brain 're-wires' after neurological disease

Trinity College researchers are studying how the brain re-wires itself in neurological disease.

24 Nov 2020

Basic concepts lay the foundation for personalized immunotherapy

Personalized Immunotherapy for Tumor Diseases and Beyond introduces personalized immunotherapy with multi-dimensional models of analysis to determine the best plan for the immunotherapy of patients.

23 Nov 2020

UTHSC and Regeneron partner to advance precision medicine

The University of Tennessee Health Science Center has entered into an agreement with the Regeneron Genetics Center, a subsidiary of Regeneron Pharmaceuticals, Inc., for the company to sequence DNA that has been voluntarily collected and stored as part of a biorepository initiative UTHSC is building in collaboration with its partner teaching hospitals.

18 Nov 2020

New AHA COVID-19 CVD Registry details the disparities in care

A new American Heart Association collaborative model for COVID-19 research, using data from the new AHA COVID-19 Cardiovascular Disease Registry, found Hispanic and Black adults with COVID-19 were far more likely to be hospitalized than their white counterparts, as were people with obesity and COVID-19, according to three late-breaking research studies presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

UCLA Health collaborates with Regeneron Genetics Center to bring genomic medicine to patients

UCLA Health has entered into a collaborative research agreement with the Regeneron Genetics Center (RGC) to provide whole exome sequencing for 150,000 UCLA Health patients.

16 Nov 2020

Baricitinib drug can reduce mortality in patients with moderate to severe COVID-19

The rheumatoid arthritis drug baricitinib can block viral entry and reduce mortality in patients with moderate to severe COVID-19, according to translational research by an international team coordinated by researchers from Karolinska Institutet in Sweden.