Respiratory News and Research

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Unique diagnostic test could help detect world's deadliest superbugs, infectious diseases

Infectious diseases such as hepatitis C and some of the world's deadliest superbugs--C. difficile and MRSA among them--could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens.

7 Jul 2015

Researchers awarded grant from British Council to reduce burden of infectious disease in Malaysia

A group of collaborators led by the University of Southampton have been awarded a British Council Newton Fund Institutional Links Grant to support ground-breaking research towards reducing the burden of infectious disease in Malaysia.

7 Jul 2015

Celtaxsys receives FDA clearance to begin acebilustat Phase 2 trial in adult CF patients in the US

Celtaxsys, Inc., a clinical stage pharmaceutical development company focusing on anti-inflammatory therapeutics, including those with rare and orphan inflammatory disease indications, announced today that it has gained clearance from the U.S. Food and Drug Administration to begin a Phase 2 clinical trial of its flagship drug candidate, acebilustat (CTX-4430), in adult CF patients in the US.

7 Jul 2015

New treatment option available for CLL patients in Manitoba and Saskatchewan

People in Manitoba and Saskatchewan living with Chronic Lymphocytic Leukemia (CLL) will now be able to access a new treatment option through the prescription drug insurance plans in both provinces. Earlier this week, GAZYVA (obinutuzumab) in combination with chlorambucil chemotherapy was added to benefits formularies of the Provincial Oncology Drug Programs at CancerCare Manitoba and the Saskatchewan Cancer Agency.

6 Jul 2015

Harvard Medical School scientists reveal structure of vesicular stomatitis virus protein

Viruses need us. In order to multiply, viruses have to invade a host cell and copy their genetic information. To do so, viruses encode their own replication machinery or components that subvert the host replication machinery to their advantage.

3 Jul 2015

Gene therapy improves lung function in patients with cystic fibrosis

Gene therapy was shown to provide significant benefits for patients with cystic fibrosis in a recent clinical study published in The Lancet Respiratory Medicine journal.

3 Jul 2015

Gene therapy for cystic fibrosis shows significant benefit in lung function

For the first time gene therapy for cystic fibrosis has shown a significant benefit in lung function compared with placebo, in a phase 2 randomised trial published in The Lancet Respiratory Medicine journal. The technique replaces the defective gene response for cystic fibrosis by using inhaled molecules of DNA to deliver a normal working copy of the gene to lung cells.

3 Jul 2015

Researchers explore how Sox9 protein regulates production of cartilage

Cartilage does a lot more than determine the shapes of people's ears and noses. It also enables people to breathe and to form healthy bones -- two processes essential to life. In a study published in Cell Reports, USC Stem Cell researcher Xinjun He and University of Tokyo researcher Shinsuke Ohba explore how a protein called Sox9 regulates the production of cartilage.

3 Jul 2015

Mortality rates vary depending on socioeconomic differences among areas in Europe

For a number of years now, scientific literature has questioned whether mortality rates depend on socioeconomic differences among the population. Recently, a new study carried out in 15 European cities - including Barcelona and Madrid - detected inequalities for the majority of causes, concluding that higher levels of poverty are associated with higher mortality rates and there is a great deal of variation among areas.

2 Jul 2015

Educational messages about naloxone's lifesaving benefits can bolster support for its use

While most Americans do not support policies designed to increase distribution of naloxone - a medication that reverses the effects of a drug overdose - certain types of educational messages about its lifesaving benefits may bolster support for its use, new Johns Hopkins Bloomberg School of Public Health research suggests.

2 Jul 2015

Domainex’s new integrated bioassay service platform accelerates progression of drug discovery projects

Domainex Ltd, a private drug discovery service company, today announces that it is launching an integrated bioassay service platform, BioassayBuilder.

2 Jul 2015

Discovery Laboratories gets notice of noncompliance from Nasdaq Stock Market related to minimum bid price

Discovery Laboratories, Inc. announced today that, on June 29, 2015, the Company received a letter from The Nasdaq Stock Market indicating that, because the Company's common stock has not maintained a minimum closing bid price of $1.00 per share over the previous 30 consecutive business days, the Company is no longer in compliance with Nasdaq's Listing Rule 5550(a)(2) (the "Minimum Bid Price Requirement").

1 Jul 2015

Study explores effects of patent foramen ovale in high-altitude Bolivian setting

A common heart feature long thought to have negligible effects on human health and performance may be problematic at high altitude, according to University of Oregon researchers.

1 Jul 2015

Aridis' Aerucin gets FDA Fast Track Designation for treatment of hospital-acquired and ventilator-associated pneumonia

Aridis Pharmaceuticals, Inc., a biopharmaceutical company applying proprietary technologies to produce novel therapies for infectious diseases, announced today that the U.S. Food and Drug Administration granted Fast Track Designation to its fully human monoclonal antibody Aerucin for the treatment of hospital-acquired and ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

30 Jun 2015

STIOLTO RESPIMAT Inhalation Spray now available for treatment of COPD across the U.S.

Boehringer Ingelheim Pharmaceuticals, Inc. announced today that STIOLTO RESPIMAT (tiotropium bromide and olodaterol) Inhalation Spray is now available by prescription at pharmacies across the United States.

30 Jun 2015

Marken to deliver clinical trial drugs in Korea during MERS outbreak

Marken, the leading clinical trial logistics organization providing solutions and services to the life sciences industry, has been granted permission by the government to deliver the first direct to patient shipment of clinical drug product in Korea.

30 Jun 2015

Study demonstrates safety and accuracy of robot-assisted telemedicine in NICU

Many hospitals lack the resources and patient volume to employ a round-the-clock, neonatal intensive care specialist to treat their youngest and sickest patients.

30 Jun 2015

American Journal of Respiratory and Critical Care Medicine publishes overview of MERS-CoV outbreak in Korea

An overview and analysis of the factors underlying the recent Middle East Respiratory Syndrome coronavirus (MERS-CoV) outbreak in Korea has been published online ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

30 Jun 2015

Two antibodies show early promise in preventing and treating MERS

As the South Korean epidemic of Middle East Respiratory Syndrome (MERS) continues unabated, researchers have raced to find treatments for the deadly virus, which has killed more than 400 people since it was first discovered three years ago in Saudi Arabia.

30 Jun 2015

Elsevier announces highlights of 2014 Impact Factor performance

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the highlights of its journal Impact Factor performance in 2014. According to the 2014 Journal Citation Reports (JCR) published by Thomson Reuters, Elsevier saw 55% of its journal Impact Factors increase from 2013 to 2014, ahead of the aggregate across other journals.

29 Jun 2015

Respiratory News and Research

Unique diagnostic test could help detect world's deadliest superbugs, infectious diseases

Researchers awarded grant from British Council to reduce burden of infectious disease in Malaysia

Celtaxsys receives FDA clearance to begin acebilustat Phase 2 trial in adult CF patients in the US

New treatment option available for CLL patients in Manitoba and Saskatchewan

Harvard Medical School scientists reveal structure of vesicular stomatitis virus protein

Gene therapy improves lung function in patients with cystic fibrosis

Gene therapy for cystic fibrosis shows significant benefit in lung function

Researchers explore how Sox9 protein regulates production of cartilage

Mortality rates vary depending on socioeconomic differences among areas in Europe

Educational messages about naloxone's lifesaving benefits can bolster support for its use

Domainex’s new integrated bioassay service platform accelerates progression of drug discovery projects

Discovery Laboratories gets notice of noncompliance from Nasdaq Stock Market related to minimum bid price

Study explores effects of patent foramen ovale in high-altitude Bolivian setting

Aridis' Aerucin gets FDA Fast Track Designation for treatment of hospital-acquired and ventilator-associated pneumonia

STIOLTO RESPIMAT Inhalation Spray now available for treatment of COPD across the U.S.

Marken to deliver clinical trial drugs in Korea during MERS outbreak

Study demonstrates safety and accuracy of robot-assisted telemedicine in NICU

American Journal of Respiratory and Critical Care Medicine publishes overview of MERS-CoV outbreak in Korea

Two antibodies show early promise in preventing and treating MERS

Elsevier announces highlights of 2014 Impact Factor performance

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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