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Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Patients with common conditions such as back pain, headaches and upper respiratory infections are more likely to receive tests and services of uncertain or little diagnostic or therapeutic benefit--so-called low-value care--when they seek treatment in primary care clinics located at hospitals rather than at community-based primary care clinics, according to a nationwide study led by researchers at Harvard Medical School and the David Geffen School of Medicine at UCLA.

10 Apr 2017

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres - the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations associated with this protein complex contributes to various cancers.

10 Apr 2017

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

If all your life, you have been functioning best in the evening and night compared to the mornings, a gene mutation may be a reason.

10 Apr 2017

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage.

7 Apr 2017

JAPhA articles highlight role of pharmacists in controlling opioid crisis

Pharmacists often face serious challenges when trying to balance the needs of patients with chronic pain and preventing prescription drug misuse, abuse, and overdose.

7 Apr 2017

New research effort aims to better understand impact and progression of COPD

Duke University's MURDOCK Study, the Duke Clinical Research Institute and Boehringer Ingelheim Pharmaceuticals Inc. announced today the launch of a new collaborative research effort to closely follow 850 people living with chronic obstructive pulmonary disease (COPD).

7 Apr 2017

FDA grants approval for two drugs to treat hepatitis C virus in children

The U.S. Food and Drug Administration today approved supplemental applications for Sovaldi (sofosbuvir) and Harvoni (ledipasvir and sofosbuvir) to treat hepatitis C virus (HCV) in children ages 12 to 17. Harvoni and Sovaldi were previously approved to treat HCV in adults.

7 Apr 2017

UC Riverside professor receives grant to explore therapeutic target for treating IBD patients

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. A protective protein that plays a key role in this disease is "T-cell protein tyrosine phosphatase" or TCPTP.

7 Apr 2017

Patients with inducible urticaria can benefit from treatment with asthma drug

Patients who develop itchy wheals in response to cold or friction benefit from treatment with omalizumab, a drug normally used to treat asthma.

7 Apr 2017

Ammonium levels in urine may help identify serious health risks in CKD patients

New research indicates that measuring ammonium excretion in the urine may be help identify patients with chronic kidney disease (CKD) who face serious health risks. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology.

7 Apr 2017

Research project aims to develop new chip-sized optical microscope with high resolution capabilities

Creating a new type of chip-sized optical microscope with high resolution capabilities is the challenge of ChipScope, a European project led by the University of Barcelona which counts with the participation of SMEs, universities and research institutes from five European countries.

6 Apr 2017

Comprehensive hospital standards released for improving quality of geriatric surgical care

The first comprehensive set of hospital-level surgical care standards for older adults has been released and published on the Annals of Surgery website in advance of print publication.

6 Apr 2017

Tumor necrosis factor may help control blood pressure, study suggests

Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure. The study is published online today in Nature Communications.

6 Apr 2017

Case Western Reserve University researchers aim to treat oral complications of HIV

While advances in HIV treatment have dramatically improved patient lifespans and quality of life, nagging side effects remain; among the most common is chronic inflammation--essentially, when an immune system imbalance causes the body to attack itself.

6 Apr 2017

Acelity launches V.A.C. VERAFLO CLEANSE CHOICE Dressing for complex wounds

C Acelity, a global advanced wound care company, today announced the global launch of the V.A.C. VERAFLO CLEANSE CHOICE Dressing, providing clinicians with a novel, adjunctive non-surgical option that may help clean large complex wounds when complete surgical debridement is not possible or appropriate.

6 Apr 2017

New finding on key protein opens door to potential therapies for chronic illnesses

Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings, published April 5 online in the journal Nature, opens doors to potential new therapies to control cardiovascular disease and pain.

6 Apr 2017

Novel point-of-care testing strategy can speed up treatment for respiratory illnesses

Doctors and researchers in Southampton have developed a novel way of using a swab test which can rapidly diagnose flu and other viral infections in patients with severe respiratory conditions - resulting in shorter courses of antibiotics and less time in hospital.

5 Apr 2017

Yoga may be valuable adjunct to conventional therapies for ulcerative colitis

Patients with ulcerative colitis, a chronic inflammatory bowel disease, often relapse at times of stress.

5 Apr 2017

Six important things to know about opioid crisis

While opioid drugs play an important role in pain management, an alarming increase in opioid diversion, opioid use disorder, and opioid-related mortality and morbidity in recent years has created a healthcare crisis in the United States.

5 Apr 2017

New EIU report highlights need for more government action to address the psoriasis challenge

A new report by the Economist Intelligence Unit (EIU) reveals governments have taken little or no action to improve care for those living with psoriasis, a chronic autoimmune disease of the skin that affects 125 million people worldwide, since the 2014 World Health Organisation Resolution, which called for global action to improve quality of life for those living with the disease.

5 Apr 2017

Chronic News and Research

Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

Study of interactions between chemokines pinpoints potential targets for treatment of inflammation

JAPhA articles highlight role of pharmacists in controlling opioid crisis

New research effort aims to better understand impact and progression of COPD

FDA grants approval for two drugs to treat hepatitis C virus in children

UC Riverside professor receives grant to explore therapeutic target for treating IBD patients

Patients with inducible urticaria can benefit from treatment with asthma drug

Ammonium levels in urine may help identify serious health risks in CKD patients

Research project aims to develop new chip-sized optical microscope with high resolution capabilities

Comprehensive hospital standards released for improving quality of geriatric surgical care

Tumor necrosis factor may help control blood pressure, study suggests

Case Western Reserve University researchers aim to treat oral complications of HIV

Acelity launches V.A.C. VERAFLO CLEANSE CHOICE Dressing for complex wounds

New finding on key protein opens door to potential therapies for chronic illnesses

Novel point-of-care testing strategy can speed up treatment for respiratory illnesses

Yoga may be valuable adjunct to conventional therapies for ulcerative colitis

Six important things to know about opioid crisis

New EIU report highlights need for more government action to address the psoriasis challenge

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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