Immune System News and Research

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Potential to reduce preterm births ‘shockingly small’

If developed countries were to successfully implement five preventive interventions, only a 5% relative reduction in the preterm birth rate could be achieved by 2015, shows a study published by The Lancet.

16 Nov 2012

Tug of war between Hsp70 and 90 determines how much the body makes of superoxide

Two proteins are in a tug of war that determines how much the body makes of superoxide, a highly reactive and potentially destructive product of oxygen that's dramatically elevated in cardiovascular disease, researchers report.

16 Nov 2012

New insights into how MSCs ‘traffic’ from the circulation into tissues

Mesenchymal stem cells (MSCs), are a newly emerging cellular therapy being tested in approximately 250 clinical trials worldwide to help repair damaged tissues, such as injured heart muscle following a heart attack. The problem is that when culture-expanded MSCs are injected into the circulation, they have trouble gaining access to the inflamed tissues-exactly where their help is needed.

16 Nov 2012

Gene therapy shows promise against dry mouth in cancer patients

Injecting an adenoviral vector encoding human aquaporin-1 into the parotid glands of head and neck cancer survivors improves their symptoms of dry mouth induced by radiation therapy, show study results.

15 Nov 2012

Triclosan exposure linked to allergies in children

Norwegian children with high levels of urinary triclosan are more likely to have allergies than children with lower levels, report researchers in Allergy.

15 Nov 2012

International research team discovers gene that nearly triples risk of Alzheimer's disease

A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team including researchers from Mayo Clinic. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years. The findings were reported Wednesday in the online edition of the New England Journal of Medicine.

15 Nov 2012

Researchers discover rare genetic mutation that increases risk of Alzheimer's disease

Researchers from Nottingham have played their part in the discovery of a rare genetic mutation that increases the risk of Alzheimer's disease, in a study with major implications for understanding the causes of the disease.

15 Nov 2012

Positive preliminary results from ImmunoPulse Phase II trial in metastatic melanoma

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumors, announces positive preliminary results from a Phase II trial investigating the use of ImmunoPulse in metastatic melanoma patients at the 6th World Meeting of Interdisciplinary Melanoma Skin Cancer Centres & 8th EADO Congress.

15 Nov 2012

Pancreas stem cells can be turned into insulin producing cells

Stem cells in the adult pancreas have been identified that can be turned into insulin producing cells, a finding that means people with type 1 diabetes might one day be able to regenerate their own insulin-producing cells.

15 Nov 2012

Scientists discover link between mutation in immune system gene and Alzheimer's disease

An international research team including scientists from the University of Toronto's Faculty of Medicine has discovered a link between a mutation in an immune system gene and Alzheimer's disease.

15 Nov 2012

Myasthenia gravis therapies: an interview with Professor Daniel Drachman

Myasthenia gravis (MG) is an autoimmune disease that produces weakness and fatiguability of muscles. It affects between 1 and 7 people per 10,000, according to the best statistics.

15 Nov 2012

Flu virus suppresses body's ability to defend against bacteria

When infected with influenza, the body becomes an easy target for bacteria. The flu virus alters the host's immune system and compromises its capacity to effectively fight off bacterial infections. Now, a team of immunologists at the Helmholtz Centre for Infection Research (HZI) and cooperation partners has discovered that an immune system molecule called TLR7 is partly to blame. The molecule recognizes the viral genome - and then signals scavenger cells of the immune system to ingest fewer bacteria.

15 Nov 2012

Pig genes resemble human genes when associated with diabetes, obesity

Insights into the genetic code of pigs that reveal how the species evolved could improve the health of animals in future.

15 Nov 2012

Obama, congressional leaders stake out positions in 'fiscal cliff' face-off

President Barack Obama and GOP congressional leaders signal what they're looking for in a budget deal to avert the looming "fiscal cliff," offering their respective takes on tax increases, spending cuts and changes to entitlement programs.

15 Nov 2012

Paxvax PXVX0200 cholera vaccine demonstrates safety and immunogenicity in Phase 1 clinical trial

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner today announced results from a Phase 1 clinical trial of PaxVax's single-dose oral cholera vaccine candidate at the 2012 American Society of Tropical Medicine and Hygiene (ASTMH) Annual Meeting in Atlanta.

15 Nov 2012

Tuberculosis pathogen has an ingenious defence mechanism against oxygen

Flemish biologists lead by Joris Messens (VIB / Vrije Universiteit Brussel) have discovered that Mycobacterium tuberculosis - the bacterium that causes tuberculosis - has an ingenious defence mechanism against oxygen. This knowledge is important in the search for a treatment for tuberculosis. 9.4 million people are infected with tuberculosis annually and 1.7 million people die as a result.

15 Nov 2012

Fevers can be helpful as a child battles an illness

For many parents discovering their child has a fever can be unnerving. It's one of the most common reasons parents call their doctor or bring their child in for medical care. Fevers are just a natural part of many illnesses and, in fact, can be helpful as a child battles an illness.

15 Nov 2012

Potential diagnostic method to identify subset of patients with chronic fatigue syndrome

For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome (CFS), a complex disorder with no known definitive cause or cure.

15 Nov 2012

Lung cancer stem cells can be isolated and grown in preclinical models

A University of Cincinnati (UC) Cancer Institute lung cancer research team reports that lung cancer stem cells can be isolated-and then grown-in a preclinical model, offering a new avenue for investigating immunotherapy treatment options that specifically target stem cells.

14 Nov 2012

EpiCept third quarter revenue increases to $0.9 million

EpiCept Corporation today reported a net loss for the three months ended September 30, 2012 of $1.1 million and a net loss for the nine months ended September 30, 2012 of $1.7 million.

14 Nov 2012

Immune System News and Research

Potential to reduce preterm births ‘shockingly small’

Tug of war between Hsp70 and 90 determines how much the body makes of superoxide

New insights into how MSCs ‘traffic’ from the circulation into tissues

Gene therapy shows promise against dry mouth in cancer patients

Triclosan exposure linked to allergies in children

International research team discovers gene that nearly triples risk of Alzheimer's disease

Researchers discover rare genetic mutation that increases risk of Alzheimer's disease

Positive preliminary results from ImmunoPulse Phase II trial in metastatic melanoma

Pancreas stem cells can be turned into insulin producing cells

Scientists discover link between mutation in immune system gene and Alzheimer's disease

Myasthenia gravis therapies: an interview with Professor Daniel Drachman

Flu virus suppresses body's ability to defend against bacteria

Pig genes resemble human genes when associated with diabetes, obesity

Obama, congressional leaders stake out positions in 'fiscal cliff' face-off

Paxvax PXVX0200 cholera vaccine demonstrates safety and immunogenicity in Phase 1 clinical trial

Tuberculosis pathogen has an ingenious defence mechanism against oxygen

Fevers can be helpful as a child battles an illness

Potential diagnostic method to identify subset of patients with chronic fatigue syndrome

Lung cancer stem cells can be isolated and grown in preclinical models

EpiCept third quarter revenue increases to $0.9 million

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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