High Throughput News and Research

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Genomatica achieves two key commercialization milestones

Genomatica announced today that it has achieved two key commercialization milestones ahead of schedule. First, the company achieved pilot-scale validation, at 3,000 liters, of the manufacturability and commercial viability of a 'green' version of 1,4-butanediol (BDO), its first commercial product. And second, the company confirmed the accelerated development time and reduced development and production costs made possible through use of its technology platform, from concept to commercialization.

30 Jun 2010

Emerald, FORMA sign strategic partnership for structure-based design of cancer drug candidates

Emerald BioStructures, a leading provider of integrated structural biology services, and FORMA Therapeutics, a drug discovery company, today announced the signing of a strategic partnership for the structure-based design of cancer drug candidates for FORMA's pipeline.

28 Jun 2010

ABL to host CRP-Santé COMET subtyping tool within TherapyEdge servers

The licensing and distribution agreement allows ABL to directly host COMET (COntext-based Modeling for Expeditious Typing) subtyping tool developed at CRP-Santé within the TherapyEdge servers; it will mainly interact with the ViroScore Suite system to characterize HIV-1 virus subtypes.

24 Jun 2010

Researchers develop experimental approaches, analysis tools to understand phenotypic expression

The Human Genome Project, along with numerous parallel efforts to solve the DNA sequences of hundreds of animal, plant, fungal, and microbe genomes in the last few decades, has produced enormous amounts of genetic data with which researchers are struggling to keep pace.

23 Jun 2010

EdgeBio introduces Science as a Service concept built on top of CLC Genomics Server

Today at the inaugural Beyond Sequencing conference in San Francisco, EdgeBio introduced their Science as a Service concept built on top of CLC bio's enterprise platform, CLC Genomics Server. EdgeBio's end-to-end service concept leads each scientist and project from conception and project design through bioinformatics and analysis.

23 Jun 2010

PAS technique to predict how blood platelets respond to complex conditions found during heart attack

A team of bioengineers from the University of Pennsylvania Institute for Medicine and Engineering have trained a computer neural network model to accurately predict how blood platelets would respond to complex conditions found during a heart attack or stroke.

21 Jun 2010

Life Technologies announces product launches in concert with ISSCR 8th Annual Meeting

Life Technologies Corporation, a provider of innovative life science solutions, today announced activities and product launches in concert with the International Society for Stem Cell Research (ISSCR) 8th Annual Meeting that highlight the company's offerings of complete end-to-end solutions for stem cell research. Stem cell research has been shown to be a critical component of regenerative medicine; a basis for identifying drug targets and drug screening; and an important step in the development of therapies to treat a variety of diseases.

18 Jun 2010

Applied BioCode's novel BMB technology to be presented at Biodetection Technologies 2010 Conference

Applied BioCode, Inc. announced today a presentation to be given on their Barcoded Magnetic Beads technology at the Biodetection Technologies 2010 Conference in Arlington, Virginia. The presentation is titled "Multiplexed Assays Go Digital" and will be given by Dr. Winston Ho, President at Applied BioCode, on June 18, 2010.

18 Jun 2010

BIOCIUS Life Sciences, BlueSky Biotech collaborate to offer Sirtuin pre-validated assay solution

BIOCIUS Life Sciences Inc., developers of the RapidFire® high-throughput mass spectrometry system, and BlueSky Biotech, service provider of discovery biologicals, today announced their collaboration to offer the industry's only Sirtuin (SIRT, silent mating type information regulation homolog) enzyme preparations fully-validated in a label-free functional assay.

16 Jun 2010

CLC bio headed molecular diagnostics project receives $2M grant

CLC bio, Ion Torrent, and Aarhus University Hospital - Departments of Molecular Medicine and Clinical Genetics, have received a 2 million USD grant from the Danish National Advanced Technology Foundation.

15 Jun 2010

WaferGen announces microRNA, oncology gene panels for SmartChip Real-Time PCR System

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced the availability of two gene expression profiling panels for the SmartChip Real-Time PCR System that will enable microRNA and cancer pathway profiling capability.

10 Jun 2010

NanoString Technologies launches new solution to detect CNVs in human genomic samples

NanoString Technologies, Inc., a privately held life sciences company marketing a complete solution for detecting and counting large sets of target molecules in biological samples, today announced the launch of its early access program for a unique new solution that detects copy number variation in human genomic samples. The program was announced in conjunction with the company's participation in the European Human Genetics Conference in Gothenburg, Sweden.

From NanoString Technologies 10 Jun 2010

Cyntellect launches Stem Cell Colony Purification Application

Cyntellect, Inc., a privately-held life sciences company commercializing products to advance the study of cell biology, stem cell research, biopharmaceutical production, and drug discovery, announced today the commercial availability of its Stem Cell Colony Purification Application powered by the LEAP™ Cell Processing Workstation.

9 Jun 2010

Takeda Rika Kogyo to distribute WaferGen's SmartChip Real-Time PCR System in Japan

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genome analysis systems, today announced the signing of an exclusive distribution agreement for the company's SmartChip Real-Time PCR System with Takeda Rika Kogyo Co., Ltd., a leading distributor of innovative products and services in the life science markets within Japan.

8 Jun 2010

Fovea's initiation of Prednisporin Phase 2b clinical testing triggers milestone payment to CombinatoRx

CombinatoRx, Incorporated today announced that it has received a milestone payment from Fovea Pharmaceuticals, a division of Sanofi Aventis, relating to Fovea's initiation of Phase 2b clinical testing of PrednisporinTM (FOV1101) in subjects with persistent allergic conjunctivitis. Prednisporin™ is a CombinatoRx-derived combination drug candidate that was exclusively licensed to Fovea by CombinatoRx.

7 Jun 2010

Researchers underscore role of jumping genes in maintaining genetic diversity

Using high-throughput sequencing to map the locations of a common type of jumping gene within a person's entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic diversity.

4 Jun 2010

Life Technologies, DKFZ collaborate to create National High-Throughput Sequencing Center

Life Technologies Corporation and the German Cancer Research Center (Deutsches Krebsforschungszentrum or DKFZ) today announced their collaboration to create the National High-Throughput Sequencing Center. This exclusive partnership will create the largest sequencing facility in Germany and the first national sequencing center in Europe dedicated to systems biology.

3 Jun 2010

Researchers discover relationship between DNA methylation and positioning of nucleosomes

A previously unknown pattern in DNA methylation - an event that affects cell function by altering gene expression - has been uncovered for the first time by stem cell researchers at UCLA, a finding that could have implications in preventing some cancers and correcting defects in human stem cell lines.

3 Jun 2010

Illumina commences shipment of new HumanOmni2.5-Quad DNA Analysis BeadChip microarray

Illumina, Inc. today announced that it has begun shipping its new HumanOmni2.5-Quad DNA Analysis BeadChip (Omni2.5). This microarray contains millions of newly discovered genome-wide common and rare variants from the 1,000 Genomes Project (1kGP), selected to maximize its ability to detect new associations.

From Illumina, Inc. 2 Jun 2010

Researchers discover bitter taste inhibitor

Researchers have discovered a chemical that specifically blocks people's ability to detect the bitter aftertaste that comes with artificial sweeteners such as saccharin. The key is a molecule known only as GIV3727 that specifically targets and inhibits a handful of human bitter taste receptors, according to a report published online on May 27th in Current Biology, a Cell Press publication.

28 May 2010