Membrane News and Research

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Study finds white adipose tissue to be the most vulnerable organ to obesity-related metabolic changes

When the body is subjected to a high-calorie diet, the physiological response is not homogeneous and some organs or tissues are more sensitive to metabolic stress.

20 Jul 2022

Biotium introduces new line of antibodies for exosome detection

ExoBrite™ Antibody Conjugates are validated and optimized for bright and specific detection of exosome markers CD9, CD63, and CD81 for flow cytometry and western blotting.

20 Jul 2022

The durability of immunity and the likelihood of breakthrough infections following vaccination with four well-studied COVID-19 vaccines

Researchers compared the durability of vaccine-induced immunity and natural infection against COVID-19.

20 Jul 2022

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

A recent study discusses the use of commensal bacteria in the gut and/or respiratory tract to deliver viral antigens to the host, thus acting as vaccines

19 Jul 2022

Researchers discover new key protection against COVID-19 in saliva

The novel coronavirus (SARS-CoV-2) has spread around the world at an unprecedented rate, evading containment countermeasures.

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

Prostaglandin E1 could enhance the safety of ECMO

In case of heart and/or lung failure, an ECMO machine can be used to maintain organ function for days or even weeks.

18 Jul 2022

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

People with a severe form of diabetes, where the beta cells of the pancreas do not produce or no longer produce enough insulin, have no choice but to inject themselves regularly with artificial insulin in order to survive.

18 Jul 2022

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Researchers screened bacterial mucosal vaccine vectors from 2015 to the present to identify a promising candidate to present SARS-CoV-2 spike protein or its fragments.

18 Jul 2022

Unique tool helps to study how the mechanical forces behind protein folding affect cancer spread

Talin is a protein that controls cellular attachment and movement, but its malfunctioning also allows cancer cells to spread. DCL1 is a tumor-suppressing protein. But scientists don't fully understand how either protein works – or what happens when they don't work the way they should.

15 Jul 2022

Tokyo Tech researchers develop the first synthetic mechanosensitive potassium channel

Intrigued by the properties of ion channel proteins commonly observed in cells, Tokyo Tech researchers have developed the first synthetic mechanosensitive potassium channel using a newly developed aromatic fluorinated amphiphilic cyclophane.

15 Jul 2022

Antibody signatures strongly associated with SARS-CoV-2 immunopathology identified using a novel B cell epitope discovery method

A recent study discovered antibody footprints strongly correlated with immunopathology of SARS-CoV-2 infection using a new B cell epitope identification approach

14 Jul 2022

The global succinylation and protein abundance in SARS-CoV-2–infected cells

Researchers assessed the global succinylation of SARS-CoV-2-infected host cells.

14 Jul 2022

MINAR2 gene mutations cause progressive hearing loss

Researchers at the John T. Macdonald Department of Human Genetics and the John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene caused deafness in four families. The gene variation mostly affects the inner ear hair cells, which are critical to hearing.

14 Jul 2022

Children born to mothers with PCOS have increased risk of developing childhood illnesses

Children born to mothers with polycystic ovary syndrome (PCOS) have an increased risk of developing infections, allergies and other childhood illnesses by the age of 13, according to the largest study to investigate this.

14 Jul 2022

Bacterial infections cause sperm dysfunction via their outer membrane vesicles

A new study discusses the impact of Escherichia coli (E. coli) infection on sperm parameters.

13 Jul 2022

Prion imaging could lead to better understanding of what causes fatal neurological disorders

Prion diseases are incurable, deadly neurological disorders that can affect both humans and animals–including Creutzfeldt-Jakob Disease (CJD) in people, Bovine Spongiform Encephalopathy (also known as Mad Cow Disease) and Chronic Wasting Disease found in deer.

13 Jul 2022

Membrane News and Research

Study finds white adipose tissue to be the most vulnerable organ to obesity-related metabolic changes

Biotium introduces new line of antibodies for exosome detection

The durability of immunity and the likelihood of breakthrough infections following vaccination with four well-studied COVID-19 vaccines

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

Researchers discover new key protection against COVID-19 in saliva

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Should siRNA-based antivirals be added to the COVID toolbox?

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

Prostaglandin E1 could enhance the safety of ECMO

Alternative therapy based on S100A9 protein improves metabolism of insulin-dependent diabetics

Future SARS-CoV-2 vaccines could hijack commensal bacteria in the gut–lung axis to confer immunity

Unique tool helps to study how the mechanical forces behind protein folding affect cancer spread

Tokyo Tech researchers develop the first synthetic mechanosensitive potassium channel

Antibody signatures strongly associated with SARS-CoV-2 immunopathology identified using a novel B cell epitope discovery method

The global succinylation and protein abundance in SARS-CoV-2–infected cells

MINAR2 gene mutations cause progressive hearing loss

Children born to mothers with PCOS have increased risk of developing childhood illnesses

Bacterial infections cause sperm dysfunction via their outer membrane vesicles

Prion imaging could lead to better understanding of what causes fatal neurological disorders

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