Metabolites News and Research

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'Smart toilet' looks for signs of disease

A Stanford study published in the journal Nature Biomedical Engineering in April 2020 reports the development of a new kind of toilet that can pick up signs of an extensive range of diseases, from molecules in stool and urine. This could be extremely useful in repeatedly and inexpensively screening high-risk groups for certain conditions, including those for which a genetic tendency is possible – such as prostate cancer or certain kinds of kidney cancer.

6 Apr 2020

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

An article published in the Journal of Medicinal Chemistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's.

3 Apr 2020

Substances linked to bladder cancer found in the urine of e-cigarette users

An analysis of evidence from multiple scientific studies found six substances that have a strong link to bladder cancer in the urine of people who had used electronic cigarettes and sometimes other tobacco products, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and NYU Langone Health reported.

19 Mar 2020

Researchers uncover possible pitfalls of common hormone analysis in animal hair

Similar to humans, wild animals' reaction to disturbance is accompanied by releasing hormones, such as cortisol.

12 Mar 2020

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Breathing dirty air takes a heavy toll on gut bacteria, boosting risk of obesity, diabetes, gastrointestinal disorders and other chronic illnesses, new University of Colorado Boulder research suggests.

11 Mar 2020

Diet influences multiple sclerosis disease course

The short-chain fatty acid propionic acid influences the intestine-mediated immune regulation in people with multiple sclerosis (MS).

11 Mar 2020

Computer program analyzes blood plasma to identify weight gain biomarkers

Researchers at the University of Campinas in São Paulo State, Brazil, have developed a computer program that analyzes molecules in blood plasma to search for biomarkers that identify individuals who are at risk of becoming overweight and developing obesity-related diseases.

10 Mar 2020

Building a 3D scaffolding to monitor tumor growth in real time and controlled environments

Building three-dimensional scaffolding to guide the growth of tumors in controlled environments, to monitor the evolution of each of their cells in real time and to record the release of tumor metabolites and other indicators of cell activity under different conditions.

9 Mar 2020

Researchers find previously unknown response within gut microbiome

The gut microbiome, which is a collection of numerous beneficial bacteria species, is key to our overall well-being and good health. Recent studies have linked the gut microbiome with several beneficial properties, such as aiding in the development of our immune system and warding off pathogen infections.

5 Mar 2020

Prebiotics could help improve sleep and boost stress resilience

Think dietary fiber is just for digestive health? Think again.

3 Mar 2020

New research cluster aims to use mass spectrometry to provide insights in systems medicine

The Mainz University Medical Center and Johannes Gutenberg University Mainz are establishing the interdisciplinary research cluster entitled "Data-Independent Acquisition-based Systems Medicine (DIASyM): Mass Spectrometry for High-Throughput Deep Phenotyping of Heart Failure Syndrome".

28 Feb 2020

Johns Hopkins researchers make progress in the development of noninvasive urine test for prostate cancer

Researchers at the Johns Hopkins Kimmel Cancer Center have made significant progress toward development of a simple, noninvasive liquid biopsy test that detects prostate cancer from RNA and other specific metabolic chemicals in the urine.

28 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Reduced stress associated with changes in plasma metabolite profile

Reduced stress is linked to changes in the profile of plasma metabolites, a new study from the University of Eastern Finland shows.

25 Feb 2020

Woman's bladder produces alcohol – a rare medical condition

A 61-year-old woman was set for a liver transplant but was denied due to a high level of alcohol in her system. Her urine contained alcohol, which is unlikely unless someone has consumed large amounts of it.

25 Feb 2020

Researchers uncover how cancer cells override environmental cues to consume energy

Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize energy use.

24 Feb 2020

Essential oil components could meet the criteria set for drug candidates

A research team at the VIB-KU Leuven Center for Microbiology and the KU Leuven Department of Biology showed that, contrary to generally held belief, most components of essential oils could meet the criteria set for drug candidates.

23 Feb 2020

Harmful levels of metal linked to DNA damage found in the urine of e-cigarette users

Researchers at the University of California, Riverside, have completed a cross-sectional human study that compares biomarkers and metal concentrations in the urine of e-cigarette users, nonsmokers, and cigarette smokers.

20 Feb 2020

Autism in young boys linked to phthalate exposure before birth

A new study published in February 2020 in the journal Environmental Health Perspectives shows that being exposed to phthalates during intrauterine life is associated with the occurrence of autistic traits in boys 3-4 years old, but not in girls. These include poor social interaction, repetitive behavior, and a narrow range of interests, stopping short of an actual diagnosis of autism.

19 Feb 2020

Bruker announces fully validated NMR module for metabolite quantification in urine (research use only)

Bruker has announced the release of the B.I.QUANT-UR™ 1.1 module, which complies with DIN-ISO criteria for the quantification of urine metabolites by NMR.

From Bruker BioSpin Division 18 Feb 2020

Metabolites News and Research

'Smart toilet' looks for signs of disease

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

Substances linked to bladder cancer found in the urine of e-cigarette users

Researchers uncover possible pitfalls of common hormone analysis in animal hair

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Diet influences multiple sclerosis disease course

Computer program analyzes blood plasma to identify weight gain biomarkers

Building a 3D scaffolding to monitor tumor growth in real time and controlled environments

Researchers find previously unknown response within gut microbiome

Prebiotics could help improve sleep and boost stress resilience

New research cluster aims to use mass spectrometry to provide insights in systems medicine

Johns Hopkins researchers make progress in the development of noninvasive urine test for prostate cancer

Ulcerative colitis and a missing microbe in the gut

Reduced stress associated with changes in plasma metabolite profile

Woman's bladder produces alcohol – a rare medical condition

Researchers uncover how cancer cells override environmental cues to consume energy

Essential oil components could meet the criteria set for drug candidates

Harmful levels of metal linked to DNA damage found in the urine of e-cigarette users

Autism in young boys linked to phthalate exposure before birth

Bruker announces fully validated NMR module for metabolite quantification in urine (research use only)

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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