Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Is COVID-19 mRNA vaccination in children associated with subsequent multisystemic hyper-inflammatory syndrome?

Researchers assessed the possibility of COVID-19 mRNA vaccines causing multisystem inflammatory syndrome in children aged 12 to 17 years in France.

20 Jan 2022

A novel assay for the rapid detection of SARS-CoV-2 variants

A new study discusses a new assay method designed by researchers to identify SARS-CoV-2 variants.

20 Jan 2022

Virucidal effect of UV and violet light on SARS-CoV-2

In a recent study published in the Journal of Photochemistry and Photobiology, a team of researchers analyzed the effect of ultraviolet (UV) and violet light of different wavelengths on the virulence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Jan 2022

Females more prone to long-term post-COVID-19 symptoms

In a recent study published in the Journal of Clinical Medicine, researchers described the results of a multi-center study (LONG-COVID-EXP-CM) that investigated sex differences in coronavirus disease 2019 (COVID-19)-related symptoms and long-term post-COVID-19 symptoms in a group of previously hospitalized COVID-19 survivors in a large Spanish population.

19 Jan 2022

SARS-CoV-2 RNA can be detected in exhaled aerosol

In a study published in the open-access journal Influenza and other Respiratory Viruses, researchers investigated if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be detected in exhaled aerosol samples obtained from coronavirus disease 2019 (COVID-19) patients during many different types of breathing and coughing. They also analyzed how SARS-CoV-2 infection may affect the size and number of exhaled aerosol particles.

19 Jan 2022

Emerging nanomaterials-based biosensor for detecting SARS-CoV-2

A new study aimed to highlight the different smart and emerging nanomaterials used to detect SARS-CoV-2.

19 Jan 2022

Study shows inequalities in addressing post-acute neurological manifestations of COVID-19

Researchers have explored the inequities in understanding and addressing the neurological complications of COVID-19 among marginalized communities in the United States.

19 Jan 2022

Wastewater-based epidemiology to predict emerging new SARS-CoV-2 variants

In a new study, researchers established a strong approach for deducing public health-relevant epidemiological metrics like relative variant abundance and variant-specific reproduction numbers from wastewater (WW)-derived deep sequenced SARS-CoV-2 genomes.

18 Jan 2022

Analyzing disease severity of SARS-CoV-2 Omicron variant using RNA dependent RNA polymerase target delay

In a new study, a team of researchers compared the severity of the SARS-CoV-2 Omicron variant to the Delta variant using the PCR proxy marker of RNA dependent RNA polymerase target delay.

18 Jan 2022

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

In this study, the researchers not only elucidate the recent bioconjugated nanomaterials for targeted diagnosis of SARS-CoV-2, but they also provide the rationale behind these developments by discussing the mechanisms and approaches.

18 Jan 2022

Officials struggle to regulate pop-up covid testing sites — and warn patients to beware

In recent months, mobile covid-19 testing tents and vans have sprouted on urban sidewalks and street curbs as demand has skyrocketed in response to the rapid spread of the omicron variant.

18 Jan 2022

Sniffer dogs detect long COVID after 1.5 years

Researchers used sniffer dogs to test the presence of SARS-CoV-2 infection in axillary sweat samples of long COVID-19 patients.

17 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

In a new study, a team of researchers demonstrated that Japan had witnessed a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant-induced endemic between August and December 2021.

17 Jan 2022

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Researchers have been investigating the Omicron epidemic in Japan and have recently released an early report on the infectious period of the disease.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

A new study investigated COVID-19 cases in an apartment complex in South Korea and explored the possibility of aerosol transmission without direct contact between infected individuals with the help of molecular phylogenetic analysis and epidemiological surveillance.

17 Jan 2022

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

In a large prospective study of just over 1,000 patients ages 17 and younger who were seen at the Baltimore Convention Center Field Hospital (BCCFH) testing site during a seven-month period last year, researchers from Johns Hopkins Medicine and collaborating institutions report that a rapid antigen test for SARS-CoV-2 — the virus that causes COVID-19 — proved highly accurate when compared to the established standard virus detection method: the polymerase chain reaction (PCR).

16 Jan 2022