Protein C News and Research

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The approved dose of ivermectin alone not useful in treating COVID-19

A new paper published on the preprint server medRxiv in April 2020 shows that the use of the already approved drug ivermectin in clinical trials to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)s not feasible. This contradicts earlier reports of its ability to suppress the virus in vitro.

27 Apr 2020

Researchers develop new method for remotely stimulating activity in deep brain regions

University of Texas at Dallas researchers have developed a promising method for remotely stimulating activity in deep brain regions, advancing understanding of how molecules act in the brain and paving the way for better cancer treatments and therapies for other diseases.

27 Apr 2020

Duke engineers awarded NSF grant to adapt fast, low-cost diagnostic tool for COVID-19

Biomedical engineers at Duke University are adapting a rapid testing platform originally designed to detect Ebola to see whether it could be of use in detecting antigens to SARS-Cov-2, the virus that causes COVID-19.

27 Apr 2020

Scientists elucidate novel disease processes involved in pulmonary fibrosis development

Working alongside research groups from Heidelberg, researchers from Charité - Universitätsmedizin Berlin have elucidated the novel disease processes involved in the development of pulmonary fibrosis.

27 Apr 2020

SARS-CoV-2 spike protein discovery could pave way for COVID-19 vaccine

Researchers at the Indian Institute of Technology, Guwahati, have made an important discovery about a viral fusion protein found on the surface of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could help researchers develop a vaccine.

27 Apr 2020

Research provides insights into how Zika virus can spread through sexual contact

Zika virus is capable of replicating and spreading infectious particles within the outermost cells lining the vaginal tract, according to new research. The findings provide the first molecular-level insights into how the virus can move from person to person through sexual contact.

27 Apr 2020

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

In what is believed to be a first-of-its-kind study to evaluate the safety of a type of immunotherapy before surgery in patients with an aggressive form of skin cancer, researchers report that the treatment eliminated pathologic evidence of cancer in nearly half of the study participants undergoing surgery.

27 Apr 2020

Investigational drug may hold benefit for patients with lung and ovarian cancers

In a first-time disclosure of IPN60090, a small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), researchers from The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Ipsen Biopharmaceuticals reported the preclinical discovery and early-stage clinical development of this novel drug. IPN60090, now under investigation in a Phase I trial, may hold benefit for certain patients with lung and ovarian cancers.

27 Apr 2020

Researchers re-purpose cancer-fighting artificial antibodies for COVID-19

Researcher Paula Bates, John Trent, and Don Miller developed a therapeutic drug that could potentially block the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 pandemic. Their research was initially aimed at helping patients suffering from multiple types of cancer.

27 Apr 2020

Recombinant protein produces neutralizing COVID-19 antibodies in primate model

A new study reports the induction of high levels of neutralizing antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing the current pandemic of COVID-19. This promising finding was reported on the preprint server bioRxiv on April 2020.

26 Apr 2020

Early Heparin therapy improves hypoxia in COVID-19 patients

The systemic use of heparin for treating severe coronavirus disease (COVID-19) showed significant improvements in oxygen exchange and overall clinical presentation of patients, as reported by a study from Brazil available on a preprint server medRxiv.

26 Apr 2020

Developing a low-cost tool to improve the speed and accuracy of crime investigations

Engineers at UC Riverside's Marlan and Rosemary Bourns College of Engineering have received a $600,000 grant from the National Institute of Justice to develop a test kit that can rapidly identify body fluids at crime scenes.

25 Apr 2020

Newly identified protein sensor regulates rate of sugar/fat conversion pathway

Scientists in Texas and Pennsylvania have identified a protein sensor that restricts how much sugar and fat our cells convert into energy during periods of starvation.

25 Apr 2020

New study indicates novel therapies for Duchenne muscular dystrophy

When an actor is unable to perform in the theatre, an understudy--ideally one with some practice in the role--can take her place on stage.

25 Apr 2020

New antibody test to identify individuals infected with COVID-19 virus

Several tests have been developed for detecting the genetic material of the SARS-CoV-2 coronavirus that causes COVID-19, but these generally only allow detection of the virus during acute infection.

25 Apr 2020

Novel protein plays key role in transduction of mechanical cues to blood vessels

Cells and tissues are far from being mere static structures. They have the ability to sense and dynamically react to external cues to ensure that they adapt to the ever-changing outside environment.

24 Apr 2020

Active ingredient from parasite larvae could help treat asthma

The larvae of the roundworm Heligmosomoides polygyrus bakeri (Hpb) need a very special environment in order to survive: They have to invade the mucosal layer of the intestine in rodents, the only place where they can then develop into adult worms capable of reproduction.

24 Apr 2020

FAU scientists aim to develop a passive vaccine against COVID-19

Nothing less than the development of a passive vaccine against Covid-19 has been undertaken by a team of scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinkum Erlangen and their partners from the Fraunhofer Institute for Cell Therapy and Immunology in Leipzig and the German Primate Centre in Göttingen.

24 Apr 2020

Syphilis bacterium likely uses a single gene to evade immune attack

The bacterium that causes syphilis, Treponema pallidum, likely uses a single gene to escape the immune system, research from UW Medicine in Seattle suggests.

24 Apr 2020

Research shows how the immune system reacts to hepatitis C viruses

If a virus penetrates a cell, the immune system reacts immediately and produces the signaling protein interferon.

24 Apr 2020

Protein C News and Research

The approved dose of ivermectin alone not useful in treating COVID-19

Researchers develop new method for remotely stimulating activity in deep brain regions

Duke engineers awarded NSF grant to adapt fast, low-cost diagnostic tool for COVID-19

Scientists elucidate novel disease processes involved in pulmonary fibrosis development

SARS-CoV-2 spike protein discovery could pave way for COVID-19 vaccine

Research provides insights into how Zika virus can spread through sexual contact

Patients with aggressive form of skin cancer can benefit from new type of immunotherapy

Investigational drug may hold benefit for patients with lung and ovarian cancers

Researchers re-purpose cancer-fighting artificial antibodies for COVID-19

Recombinant protein produces neutralizing COVID-19 antibodies in primate model

Early Heparin therapy improves hypoxia in COVID-19 patients

Developing a low-cost tool to improve the speed and accuracy of crime investigations

Newly identified protein sensor regulates rate of sugar/fat conversion pathway

New study indicates novel therapies for Duchenne muscular dystrophy

New antibody test to identify individuals infected with COVID-19 virus

Novel protein plays key role in transduction of mechanical cues to blood vessels

Active ingredient from parasite larvae could help treat asthma

FAU scientists aim to develop a passive vaccine against COVID-19

Syphilis bacterium likely uses a single gene to evade immune attack

Research shows how the immune system reacts to hepatitis C viruses

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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