Protein C News and Research

RSS

New genome-editing techniques could make recombinant-protein drugs cheaper

The mammalian cell lines that are engineered to produce high-value recombinant-protein drugs also produce unwanted proteins that push up the overall cost to manufacture these drugs. These same proteins can also lower drug quality

24 Apr 2020

Goblet cells in the human nasal passage may play key role in enabling COVID-19 infections

Two significant international studies involving hundreds of scientists, including a human geneticist at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that specific cells in the human nasal passage shaped like a champagne glass, known as goblet cells, may play a significant role in enabling COVID-19 infections.

24 Apr 2020

Scientists are developing synthetic COVID-19 antibody to treat sick patients

A team of researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with GenScript, is developing a synthetic antibody to SARS-CoV-2, the virus that causes coronavirus disease (COVID-19). This antibody is intended to block the virus from entering human lung cells, and would be another potential treatment option for COVID-19.

24 Apr 2020

Australian researchers develop world’s first ultrasound biosensor

Australian researchers have made a world-first breakthrough that has the potential to monitor the changes in pH levels and other responses to therapy in stroke and cancer patients.

24 Apr 2020

Combination therapy boosts the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

Study: JNK and BNP activity can reverse cardiovascular damage, reduce risk of death from sepsis

Overreaction is rarely useful, and in the case of the human immune system, it can be outright deadly. When the body overreacts to an infection, the result is sepsis - a life-threatening condition that frequently leads to acute organ dysfunction, including deterioration of the heart and blood vessels, which make up the cardiovascular system.

24 Apr 2020

Research looks at best ways to tackle coronavirus crisis

A new study published in the journal Frontiers in Microbiology in April 2020 discusses the most attractive approaches among the broad spectrum of experimental and theoretical strategies being worked on to counter the COVID-19 pandemic.

24 Apr 2020

SARS-CoV-2 targets specific cells in the lung, nasal passage, and intestine

Now, the researchers from the Massachusetts Institute of Technology (MIT) have identified specific types of cells that are targets of the SARS-CoV-2 that causes the COVID-19 pandemic. The findings of the study published in the journal Cell may help in developing novel therapeutics to combat the deadly viral infection.

23 Apr 2020

A protein discovery could pave way to better treatments for obesity

A USC-led international team of scientists has found the precise shape of a key player in human metabolism, which could lead the way to better treatments for obesity and other metabolic disease.

23 Apr 2020

Bayreuth researchers discover natural protective mechanism against cancer

Susanne Hellmuth and Olaf Stemmann from the Chair of Genetics at the University of Bayreuth have discovered a natural protective mechanism that leads to the programmed death of potentially diseased cells.

23 Apr 2020

New nanobiosensor can help diagnose early-stage multiple sclerosis

Researchers at the Federal University of São Carlos in Sorocaba have developed a technique to diagnose early-stage multiple sclerosis, a disease of the central nervous system, and distinguish it from neuromyelitis optica, a rare yet severe autoimmune inflammatory process also affecting the central nervous system.

23 Apr 2020

RAS inhibitors and COVID-19 severity in hypertensive patients

A new study published in the journal JAMA Cardiology in April 2020 reports that patients with hypertension who are taking medications called ACE inhibitors (ACEI) or ARBs are not at higher risk for death or more severe illness with COVID-19. This conclusion supports current guidelines for the treatment of hypertension during this pandemic.

23 Apr 2020

Researchers discover physiological mechanisms underlying pediatric B-ALL

B-cell acute lymphoblastic leukemia (B-ALL) is characterized by the accumulation of abnormal immature B-cell precursors in the bone marrow and is the most common pediatric cancer.

23 Apr 2020

EPFL scientists identify new therapeutic target for Non-Hodgkin lymphoma

Non-Hodgkin lymphoma is a group of cancers that originate in the lymph nodes and affect white blood cells of the immune system called B cells.

23 Apr 2020

Study identifies key nose cells as likely COVID-19 virus entry points

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells.

23 Apr 2020

A faster and easier treatment option to prevent blindness in preterm infants

Babies born prematurely who require treatment to prevent blindness from retinopathy of prematurity (ROP) could be treated with a dose of Avastin (bevacizumab) that is a fraction of the dose commonly used for ROP currently.

23 Apr 2020

Higher levels of specific gene can indicate better prognosis in prostate cancer

The most common form of cancer in older men is prostate cancer. In many cases the tumor grows slowly and can be treated effectively, but it is sometimes more aggressive and becomes terminal.

23 Apr 2020

Ablexis, AlivaMab Discovery Services, and Berkeley Lights Collaborate to Identify a Diverse Panel of Anti-SARS-CoV-2 Human Antibodies

Ablexis, LLC, ADS, and Berkeley Lights, Inc. today announced the generation and recovery of sequences against the S1 spike protein of the SARS-CoV-2 virus.

From Bruker Cellular Analysis 23 Apr 2020

Researchers develop new blood test for Alzheimer's disease

A new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of Gothenburg, Sweden. The method is based on measuring a specific variant of tau protein in ordinary blood samples, which makes the test relatively simple and cheap to perform.

23 Apr 2020

Researchers demonstrate how TB bacteria import vitamin B12 molecules to grow

Researchers from Russia, the Netherlands, Sweden, and the U.S. have revealed the structure of the protein responsible for vitamin B12 import into the cells of the bacterium that causes tuberculosis. The research findings were published in Nature.

23 Apr 2020