covid 19 News and Research

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SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

A new study published on the bioRxiv preprint server aims to identify specific viral epitopes on the spike protein from various regions of the spike protein and the T cell responses they evoke.

27 Jan 2021

Flu vaccinations for hospital workers can substantially reduce influenza-related deaths

Pneumonia and the flu kill tens of thousands of Americans each year, racking up billions of dollars in medical costs and even more in lost productivity.

27 Jan 2021

Looming eviction crisis may put Californians at increased risk for unmet medical needs

Research published in the peer-reviewed Journal of General Internal Medicine found that Californians who had moved due to unaffordable housing are significantly more likely to report unmet medical needs compared to people with non-cost-related moves.

27 Jan 2021

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Now, in new research posted to the preprint server bioRxiv*, scientists use an experimental structure of the Spike RBD domain co-crystallized with part of the ACE2 receptor and several in silico methods to analyze the possible impacts of three amino acid replacements (Spike K417N, E484K, N501Y) concerning ACE2 binding.

27 Jan 2021

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Cell phone data that is routinely collected by telecommunications providers can reveal changes of behavior in people who are diagnosed with a flu-like illness, while also protecting their anonymity, a new study finds.

26 Jan 2021

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

26 Jan 2021

Remdesivir disrupts SARS-CoV-2 more effectively than other similar drugs

In the treatment of SARS-CoV-2, the virus that causes COVID-19, antiviral drug remdesivir has emerged as a promising candidate.

26 Jan 2021

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Blood draws are no fun. They hurt. Veins can burst, or even roll - like they're trying to avoid the needle too, Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and sepsis.

26 Jan 2021

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Using more than 100,000 virus genome sequences uploaded in the GISAID database, researchers found around 9,000 mutations in the virus spike protein RBD.

26 Jan 2021

Rapid reopening crucial in promoting the second wave of COVID-19

The spread of the coronavirus disease 2019 (COVID-19) has affected almost a hundred million people, with over two million deaths being attributed to this illness over the past 12 months or so. The only means to counter this so far has been through non-pharmaceutical interventions (NPIs).

26 Jan 2021

Antibodies and inflammatory markers may help identify COVID-19 cases and predict severity

A new preprint appearing on the medRxiv server describes the changes that occur in numerous antibodies and inflammatory molecules with age and at varying stages, or severity, of the infection and resulting illness. The results may help to predict the risk in individual cases.

26 Jan 2021

'Post-acute COVID-19 syndrome' likely to substantially impact NHS in England

Researchers in the UK have warned that cardiometabolic and pulmonary events among coronavirus disease 2019 (COVID-19) survivors following their discharge from hospital is likely to have an ongoing and substantial impact on the National Health Service (NHS) in England.

26 Jan 2021

Microwaves used to inactivate aerosolized pathogens

As the pandemic has continued to spread globally, studies indicate the COVID-19 virus may be contained in aerosols that can be generated and spread through breathing, coughing, sneezing, or talking by infected individuals.

26 Jan 2021

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease.

26 Jan 2021

Moderna vaccine fully neutralizes new SARS-CoV-2 variants, study shows

Researchers in the United States have conducted a study showing that Moderna’s mRNA-1273 vaccine neutralizes all circulating variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tested to date.

26 Jan 2021

NIH launches database to collect information about COVID-19-related neurological problems

A new database will collect information from clinicians about COVID-19-related neurological symptoms, complications, and outcomes as well as COVID-19 effects on pre-existing neurological conditions.

26 Jan 2021

Why even presidential pressure might not get more vaccine to market faster

Americans are dying of covid-19 by the thousands, but efforts to ramp up production of potentially lifesaving vaccines are hitting a brick wall.

26 Jan 2021

California’s top hospital lobbyist cements influence in covid crisis

As intensive care units filled and coronavirus cases surged over the holidays, Carmela Coyle invoked a World War II-era quote attributed to British Prime Minister Winston Churchill to rally her own troops: "If you're going through hell, keep going."

26 Jan 2021

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

A new approach to mapping viral mutations that "escape" leading clinical antibodies has revealed mutations in the SARS-CoV-2 virus that allow it to evade treatments, including a single amino-acid mutation that fully escapes Regeneron's antibody cocktail.

26 Jan 2021

Big business boosts vaccine effort, but it’s ‘complex choreography’ to get shots in arms

As states await the promise of a renewed federal pandemic response and expand the number of Americans who qualify for a shot, some governors are trying to scale up their covid vaccine operations — and smooth out the kinks — with the help of the private sector.

26 Jan 2021

covid 19 News and Research

SARS-CoV-2 spike may impair antigen presentation by CD8 T cells

Flu vaccinations for hospital workers can substantially reduce influenza-related deaths

Looming eviction crisis may put Californians at increased risk for unmet medical needs

Rapid transmission of N501Y variants may be due to favorable effects on host receptor binding

Cell phone data can reveal behavioral changes in people diagnosed with flu-like illness

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Remdesivir disrupts SARS-CoV-2 more effectively than other similar drugs

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Rapid reopening crucial in promoting the second wave of COVID-19

Antibodies and inflammatory markers may help identify COVID-19 cases and predict severity

'Post-acute COVID-19 syndrome' likely to substantially impact NHS in England

Microwaves used to inactivate aerosolized pathogens

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Moderna vaccine fully neutralizes new SARS-CoV-2 variants, study shows

NIH launches database to collect information about COVID-19-related neurological problems

Why even presidential pressure might not get more vaccine to market faster

California’s top hospital lobbyist cements influence in covid crisis

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

Big business boosts vaccine effort, but it’s ‘complex choreography’ to get shots in arms

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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