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Turning breast cancer cells into fat cells prevents the formation of metastases

An innovative combination therapy can force malignant breast cancer cells to turn into fat cells. This can be used to prevent the formation of metastases in mice, as researchers at the University of Basel's Department of Biomedicine recently reported in the journal Cancer Cell.

14 Jan 2019

Scientists discover mutational signatures of tumor hypoxia

Researchers have discovered mutational signatures of tumor hypoxia in 19 cancer types that could be used to identify patients who need higher treatment doses.

14 Jan 2019

New path for treating Latino immigrants with mental health and substance misuse symptoms

A team of researchers at the Disparities Research Unit at Massachusetts General Hospital (MGH) - in collaboration with two teams in Spain and collaborators in the U.S. and Puerto Rico - has tested a novel preventive intervention designed to provide tailored treatment for Latino immigrants with both mental health and substance misuse symptoms.

11 Jan 2019

New potential immunotherapy target in pancreatic cancer identified

Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.

11 Jan 2019

New research could have a significant impact on cancer therapy

Research led by Suresh Alahari, PhD, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has found a new role for a protein discovered by his lab in preventing the growth and spread of breast cancer.

11 Jan 2019

Review examines what influences HIV-positive patients to stay on antiretroviral drugs in Africa

An international team of researchers have carried out a review of the evidence examining what influences people who are HIV positive to go to health services and then stay on antiretroviral drugs in Africa.

11 Jan 2019

New analytic model can accurately predict patients at risk of developing PTSD

New findings from an international research team led by psychiatrists at NYU School of Medicine show that a newly-developed analytic model can predict soon after a shocking or scary event - and with significant accuracy -- the likelihood of someone developing Post-Traumatic Stress Disorder.

11 Jan 2019

Clinigen, Accord Healthcare extend exclusive European clinical trial supply agreement

Clinigen Group plc, the global pharmaceutical and services company, announces that its Clinical Trial Service business has extended its exclusive European clinical trial supply agreement with Accord Healthcare. Clinigen is also offering pharma companies an ‘on demand’ service to Accord’s products, a first for the industry.

From Clinigen Group 11 Jan 2019

Study raises hopes for new approaches to treat osteoporosis

A handful of brain cells deep in the brain may play a surprising role in controlling women's bone density, according to new research by UC San Francisco and UCLA scientists.

11 Jan 2019

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX.

11 Jan 2019

Clinical evidence firmly confirms the HIV Undetectable = Untransmittable concept

In recent years, an overwhelming body of clinical evidence has firmly established the HIV Undetectable = Untransmittable concept as scientifically sound, say officials from the National Institutes of Health.

11 Jan 2019

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Spondyloarthritis is one of the most common types of chronic joint inflammation affecting nearly 1-2% of the Western population.

10 Jan 2019

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

Most patients with ulcerative colitis have mild-to-moderate disease characterized by periods of activity or remission, but practice variations exist in disease management.

10 Jan 2019

New biomarker may help better predict outcomes in patients with HPV-related head and neck cancers

By analyzing variations in the level of human papillomavirus (HPV) in head and neck cancers, researchers at The University of Texas MD Anderson Cancer Center have discovered a gene signature associated with treatment response and survival in patients.

10 Jan 2019

Novel biomarker links tumor progression to genome instability

Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and the food we eat.

10 Jan 2019

Aptamer Group and AstraZeneca to develop new drug delivery vehicles

Aptamer Group today announced it has signed an agreement with AstraZeneca to explore the potential of using aptamer technology to target the kidney.

From AstraZeneca 10 Jan 2019

Measures of biochemical hypoglycemia linked to high risk of severe hypoglycemic events

Researchers have shown that measures of biochemical hypoglycemia in fingerstick blood samples are associated with an increased risk of severe hypoglycemic events.

10 Jan 2019

New findings bring about better understanding of many cancers' metabolic needs

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism.

10 Jan 2019

Aggressive prostate cancer linked to hereditary breast cancer, confirms study

Aggressive prostate cancer, one of the leading causes of cancer deaths in men, is associated with BRCA2 mutations, which are also linked to hereditary breast cancer, ovarian cancer and pancreas cancer, among others.

10 Jan 2019

New study finds link between childhood abuse and suicide in later life

Children who experience physical, sexual, and emotional abuse or neglect are at least two to three times more likely to attempt suicide in later life, according to the largest research review carried out of the topic.

9 Jan 2019

Therapy News and Research

Turning breast cancer cells into fat cells prevents the formation of metastases

Scientists discover mutational signatures of tumor hypoxia

New path for treating Latino immigrants with mental health and substance misuse symptoms

New potential immunotherapy target in pancreatic cancer identified

New research could have a significant impact on cancer therapy

Review examines what influences HIV-positive patients to stay on antiretroviral drugs in Africa

New analytic model can accurately predict patients at risk of developing PTSD

Clinigen, Accord Healthcare extend exclusive European clinical trial supply agreement

Study raises hopes for new approaches to treat osteoporosis

New method modifies blood stem cells to reverse genetic mutation that causes IPEX

Clinical evidence firmly confirms the HIV Undetectable = Untransmittable concept

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

AGA's new clinical guideline to help manage patients with mild-to-moderate ulcerative colitis

New biomarker may help better predict outcomes in patients with HPV-related head and neck cancers

Novel biomarker links tumor progression to genome instability

Aptamer Group and AstraZeneca to develop new drug delivery vehicles

Measures of biochemical hypoglycemia linked to high risk of severe hypoglycemic events

New findings bring about better understanding of many cancers' metabolic needs

Aggressive prostate cancer linked to hereditary breast cancer, confirms study

New study finds link between childhood abuse and suicide in later life

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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