Immune System News and Research

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Induced-pluripotent stem cells not as genetically unstable as previously thought

Stanford University School of Medicine scientists have demonstrated, in a study conducted jointly with researchers at Yale University, that induced-pluripotent stem cells - the embryonic-stem-cell lookalikes whose discovery a few years ago won this year's Nobel Prize in medicine - are not as genetically unstable as was thought.

19 Nov 2012

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

In a mouse model of multiple sclerosis (MS), researchers funded by the National Institutes of Health have developed innovative technology to selectively inhibit the part of the immune system responsible for attacking myelin-the insulating material that encases nerve fibers and facilitates electrical communication between brain cells.

18 Nov 2012

MusculoskeletalNetwork features special coverage of sessions from ACR annual meeting

UBM Medica US announces that MusculoskeletalNetwork features special coverage of sessions from the annual meeting of the American College of Rheumatology (ACR), including the latest information about new FDA processes for approval of biosimilars that are like generic versions of expensive medications now used to treat painful rheumatologic conditions such as rheumatoid arthritis (RA).

17 Nov 2012

Scientists discover new mode of action for enzymes immersed in cellular membranes

Johns Hopkins scientists have discovered a new mode of action for enzymes immersed in cellular membranes. Their experiments suggest that instead of recognizing and clipping proteins based on sequences of amino acids, these proteases' location within membranes gives them the unique ability to recognize and cut proteins with unstable structures.

17 Nov 2012

Researchers discover health similarities between humans and pigs

An international scientific collaboration that includes two Kansas State University researchers is bringing home the bacon when it comes to potential animal and human health advancements, thanks to successfully mapping the genome of the domestic pig.

17 Nov 2012

Study illuminates how Aldo and galectin-3 protein contribute to vascular remodeling, CHF

Cardiovascular disease will kill nearly 2.5 million people in the United States this year, according to the Centers for Disease Control. Over time, inflammation, collagen deposition and scar tissue formation can cause blood vessels to stiffen, a process called vascular fibrosis. Though researchers have known that the hormone aldosterone (Aldo) plays a role in this process, the precise mechanisms have been poorly understood.

17 Nov 2012

Textile pressure ulcer prevention

The skin is the most versatile of our organs: It protects the body from environmental effects, contributes to the body's immune system and supports metabolic functions such as breathing.

17 Nov 2012

Tregs appears to play an important role in suppressing immune response in advance of sepsis

Following an infection, dysregulation of the immune system can result in a systemic inflammatory response and an often fatal condition called severe sepsis or septic shock. Sepsis is not uncommon, yet its cause and underlying immune dysfunction remain poorly understood.

17 Nov 2012

Vitiligo patients have low risk for skin cancer

Evidence suggests that patients with vitiligo have a reduced risk for both melanoma and nonmelanoma skin cancer.

16 Nov 2012

Potential to reduce preterm births ‘shockingly small’

If developed countries were to successfully implement five preventive interventions, only a 5% relative reduction in the preterm birth rate could be achieved by 2015, shows a study published by The Lancet.

16 Nov 2012

Tug of war between Hsp70 and 90 determines how much the body makes of superoxide

Two proteins are in a tug of war that determines how much the body makes of superoxide, a highly reactive and potentially destructive product of oxygen that's dramatically elevated in cardiovascular disease, researchers report.

16 Nov 2012

New insights into how MSCs ‘traffic’ from the circulation into tissues

Mesenchymal stem cells (MSCs), are a newly emerging cellular therapy being tested in approximately 250 clinical trials worldwide to help repair damaged tissues, such as injured heart muscle following a heart attack. The problem is that when culture-expanded MSCs are injected into the circulation, they have trouble gaining access to the inflamed tissues-exactly where their help is needed.

16 Nov 2012

Gene therapy shows promise against dry mouth in cancer patients

Injecting an adenoviral vector encoding human aquaporin-1 into the parotid glands of head and neck cancer survivors improves their symptoms of dry mouth induced by radiation therapy, show study results.

15 Nov 2012

Triclosan exposure linked to allergies in children

Norwegian children with high levels of urinary triclosan are more likely to have allergies than children with lower levels, report researchers in Allergy.

15 Nov 2012

International research team discovers gene that nearly triples risk of Alzheimer's disease

A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team including researchers from Mayo Clinic. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years. The findings were reported Wednesday in the online edition of the New England Journal of Medicine.

15 Nov 2012

Researchers discover rare genetic mutation that increases risk of Alzheimer's disease

Researchers from Nottingham have played their part in the discovery of a rare genetic mutation that increases the risk of Alzheimer's disease, in a study with major implications for understanding the causes of the disease.

15 Nov 2012

Positive preliminary results from ImmunoPulse Phase II trial in metastatic melanoma

OncoSec Medical Inc., a company developing its advanced-stage ImmunoPulse DNA-based immunotherapy and NeoPulse therapy to treat solid tumors, announces positive preliminary results from a Phase II trial investigating the use of ImmunoPulse in metastatic melanoma patients at the 6th World Meeting of Interdisciplinary Melanoma Skin Cancer Centres & 8th EADO Congress.

15 Nov 2012

Immune System News and Research

Induced-pluripotent stem cells not as genetically unstable as previously thought

NIH-funded scientists develop new treatment to combat autoimmune disorders in mouse model

MusculoskeletalNetwork features special coverage of sessions from ACR annual meeting

Scientists discover new mode of action for enzymes immersed in cellular membranes

Researchers discover health similarities between humans and pigs

Study illuminates how Aldo and galectin-3 protein contribute to vascular remodeling, CHF

Textile pressure ulcer prevention

Tregs appears to play an important role in suppressing immune response in advance of sepsis

Vitiligo patients have low risk for skin cancer

Potential to reduce preterm births ‘shockingly small’

Tug of war between Hsp70 and 90 determines how much the body makes of superoxide

New insights into how MSCs ‘traffic’ from the circulation into tissues

Gene therapy shows promise against dry mouth in cancer patients

Triclosan exposure linked to allergies in children

International research team discovers gene that nearly triples risk of Alzheimer's disease

Researchers discover rare genetic mutation that increases risk of Alzheimer's disease

Positive preliminary results from ImmunoPulse Phase II trial in metastatic melanoma

Pancreas stem cells can be turned into insulin producing cells

Scientists discover link between mutation in immune system gene and Alzheimer's disease

Myasthenia gravis therapies: an interview with Professor Daniel Drachman

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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