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Researchers identify biological mechanism in depressed individuals

University of Illinois at Chicago researchers report that in depressed individuals there are increased amounts of an unmodified structural protein, called tubulin, in lipid rafts - fatty sections of a cell membrane - compared with non-depressed individuals.

22 Apr 2020

Research: Peptide makes older antibiotics effective again at doses 100 times lower than usual

A peptide renders older antibiotics effective again at doses 100 times lower than the common dosage, as shown by research from örebro University.

22 Apr 2020

Scientists identify new biomarker to detect subclinical atherosclerosis

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Instituto de Investigación Sanitaria-Fundación Jiménez Díaz in Madrid have demonstrated that a proteins present in early atheroma plaques--accumulations of cholesterol in the wall of arteries--could be used as a biomarker to detect atherosclerosis in the subclinical phase, before the appearance of symptoms.

21 Apr 2020

USPTO grants patent to TAU scientist for innovative coronavirus vaccine design

Researchers worldwide are racing at breakneck speed to develop potential vaccines and drugs to fight the novel coronavirus, SARS-Cov-2.

21 Apr 2020

CRISPR helps identify new protein potentially involved in Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease.

21 Apr 2020

Experts identify new protein that leads to Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease.

21 Apr 2020

Antibodies against Imood could be potential treatment for OCD

Mental health conditions such as obsessive compulsive disorder could be treated in a new way using drugs that target the immune system, research suggests.

21 Apr 2020

Advanced paternal age associated with risk of neurodevelopmental disorders in children

It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.

21 Apr 2020

Bio-Rad Introduces Anti-Ipilimumab Antibodies

Bio-Rad Laboratories, Inc has extended its range of recombinant monoclonal anti-idiotypic antibodies.

21 Apr 2020

Discovery could open door to the development of new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

20 Apr 2020

ACE2 receptor expression by SARS-CoV-2 across different animal species

A new report published on the preprint server bioRxiv in April 2020 reports that several species of animals can be infected with relative ease by the SARS-CoV-2 virus that is the causative agent of the currently raging COVID-19 pandemic. This casts much light on the possible natural hosts and routes of transmission of this virus.

20 Apr 2020

Mutations in novel coronavirus make it more dangerous

A new report published on the preprint server medRxiv in April 2020 reveals that the novel coronavirus SARS-CoV-2 shows the presence of new mutations acquired within infected human cases, which significantly increase its ability to cause human disease.

20 Apr 2020

Scientists delay onset of amyotrophic lateral sclerosis in mice

A team of researchers led by scientists at the University of Toronto has delayed the onset of amyotrophic lateral sclerosis in mice.

20 Apr 2020

ACE2-TMPRSS2 profiling indicates tissue vulnerability to SARS-CoV-2 infection

A new study published in April 2020 on the preprint server bioRxiv reports that the different levels of susceptibility of various organs to viral attack by the SARS-CoV-2 virus causing the huge pandemic of COVID-19 sweeping around the world can be predicted from the level of expression of two molecules, the ACE2 receptor, and the TMPRSS2 protein.

20 Apr 2020

Do ACE inhibitors increase SARS-CoV-2 binding to ACE2?

The COVID-19 pandemic has forced clinicians and academicians to intensive research to find evidence for many conventional therapies. A new round-up editorial published in the journal Cardiovascular Research in April 2020 summarizes the current clinical grounds for and against the use of the commonly used angiotensin axis inhibitors in patients with COVID-19.

20 Apr 2020

New biosensor rapidly detects SARS-CoV-2 from nasopharyngeal swabs

According to many experts, early diagnosis and management are critical for slowing the spread of SARS-CoV-2, the new coronavirus that causes COVID-19.

20 Apr 2020

A novel method for predicting promising antiviral drug or vaccine targets

A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell.

20 Apr 2020

EMBL-EBI and partners launch new COVID-19 Data Portal

EMBL's European Bioinformatics Institute and partners today launched the COVID-19 Data Portal, which enables the sharing and analysis of data related to the new coronavirus, SARS-CoV-2.

20 Apr 2020

Using genome-wide CRISPR technology to identify leukemia's weakness

A team of researchers at University of California San Diego School of Medicine and Moores Cancer Center used CRISPR technology to identify key regulators of aggressive chronic myeloid leukemia, a type of cancer that remains difficult to treat and is marked by frequent relapse.

20 Apr 2020

Hypertensive pregnancy disorders may lead to mental health conditions in children

Hypertensive pregnancy disorders, especially preeclampsia, a form of high blood pressure during pregnancy, may lead to adverse mental health conditions in children, according to new research published today in Hypertension, an American Heart Association journal.

20 Apr 2020