Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

New strategic collaboration to accelerate treatments for unmet medical needs in oncology

The University of Texas MD Anderson Cancer Center and Taiho Pharmaceutical Co., Ltd., today announced a three-year strategic collaboration to accelerate the development of treatments for significant unmet medical needs in oncology, including patients with brain metastases and those with cancers refractory to available therapies.

25 Sep 2020

Researchers use natural pigment for screening cell viability

Synthetic dyes are commonly used to assess the toxicity of chemical compounds in cell cultures. However, these dyes damage cells, rendering the cultures useless for long-term experiments.

25 Sep 2020

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Gruthan Bioscience, LLC, a Medical University of South Carolina startup based in Charleston, South Carolina, received a Small Business technology Transfer (STTR) award from the National Heart, Blood and Lung Institute in August to take the next step in developing a novel class of cholesterol-lowering drugs to treat familial hypercholesterolemia.

24 Sep 2020

Researchers identify a potential drug candidate for hand, foot and mouth disease

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. Researchers have identified a potential new drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children

22 Sep 2020

Drug used to treat breast and ovarian cancer can transform treatment for prostate cancer

A drug used to treat breast and ovarian cancer can extend the lives of some men with prostate cancer and should become a new standard treatment for the disease, concludes a major trial which is set to change clinical practice.

21 Sep 2020

Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques

Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans.

18 Sep 2020

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Psychedelic drugs such as LSD, psilocybin, and mescaline cause severe and often long-lasting hallucinations, but they show great potential in treating serious psychiatric conditions, such as major depressive disorder.

18 Sep 2020

Azelastine antihistamine inhibits SARS-CoV-2 infection in nasal tissue in vitro

In a study published on the bioRxiv preprint server, researchers from the University of Pécs, University of Vienna, and CEBINA GmbH, Vienna, show the ability of the antihistamine azelastine to inhibit SARS-CoV-2 infection in human nasal tissue in vitro.

16 Sep 2020

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Curi Bio today announced the Mantarray™ platform for human-relevant 3D engineered muscle tissue (EMT) analysis.

From Curi Bio 16 Sep 2020

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Fondazione Santa Lucia IRCCS, and Università Cattolica del Sacro Cuore in Rome have shown that pharmacological (drug) correction of the content of extracellular vesicles released within dystrophic muscles can restore their ability to regenerate muscle and prevent muscle scarring (fibrosis).

15 Sep 2020

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

15 Sep 2020

Aigenpulse launches data analysis suite to automate flow cytometry

Aigenpulse is launching its CytoML Experiment Suite specifically aimed at streamlining and automating cytometry analysis at scale.

15 Sep 2020

Evonetix partners with Analog Devices to fast track the development of DNA desktop writer

EVONETIX LTD, the synthetic biology company developing a desktop platform for scalable, high-fidelity and rapid gene synthesis, today announced a collaboration with leading, global high-performance analog technology company, Analog Devices, Inc.

15 Sep 2020

Cell signaling research rings warning bells over an emerging cancer drug target

Researchers at the Babraham Institute have used their understanding of cellular signalling to highlight a pitfall in an emerging treatment for cancer and inflammation.

14 Sep 2020

CN Bio partners with Imperial College London to uncover therapeutic targets for alcoholic hepatitis

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems to improve the accuracy and efficiency of drug discovery, today announced a collaboration with Imperial College London, a world-class research university.

10 Sep 2020

Optibrium’s peer-reviewed study highlights the value of deep learning to impute drug discovery data

Optibrium, leading providers of software and services for drug discovery, today announced a peer-reviewed publication, ‘Practical Applications of Deep Learning to Impute Heterogeneous Drug Discovery Data’, in the Journal of Chemical Information and Modeling.

10 Sep 2020

Drug Discovery News and Research

Further Reading

New strategic collaboration to accelerate treatments for unmet medical needs in oncology

Researchers use natural pigment for screening cell viability

Gruthan Bioscience to develop new class of cholesterol-lowering drugs

Researchers identify a potential drug candidate for hand, foot and mouth disease

Drug used to treat breast and ovarian cancer can transform treatment for prostate cancer

Molecular imaging probe reveals Alzheimer's-related γ-secretase in rodents, macaques

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Azelastine antihistamine inhibits SARS-CoV-2 infection in nasal tissue in vitro

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

New clinical trial shows combination of two innovative precision medicines could treat multiple cancers

Aigenpulse launches data analysis suite to automate flow cytometry

Evonetix partners with Analog Devices to fast track the development of DNA desktop writer

Cell signaling research rings warning bells over an emerging cancer drug target

CN Bio partners with Imperial College London to uncover therapeutic targets for alcoholic hepatitis

Optibrium’s peer-reviewed study highlights the value of deep learning to impute drug discovery data

Novel drug could improve life expectancy and quality for patients with hard-to-treat cancers

Insilico Medicine launches new system for COVID-19 basic and clinical research

Metrion Biosciences strengthens global business development team

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

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