Neurodegenerative Diseases News and Research

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Study discovers potential new way to slow progression of Alzheimer's

If we can overcome the loss of a process in the brain called "RNA editing", we may be able to slow the progress of Alzheimer's disease and other synaptic disorders, a new study has shown.

28 Feb 2020

Research reveals key role of a protein in rare Batten disease

Professor Stéphane Lefrançois, a researcher at the Institut National de la Recherche Scientifique (INRS), is working on Batten disease, a neurodegenerative genetic disease that primarily affects children. His research focuses on the most common form of the disease - Batten CLN 3 - which is caused by mutations in the protein of the same name and for which there is still no cure.

28 Feb 2020

Study shows how cellular filament helps neural stem cells clear damaged, clumped proteins

New research by University of Wisconsin-Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons.

28 Feb 2020

Scientists reveal ability to reverse Huntington's disease-causing DNA repeat mutations in the lab

Neurodegenerative diseases, like Huntington's disease and myotonic dystrophy, are often referred to as DNA repeat diseases, named because of long repeated sequences in the DNA of patients. Increasing repeat expansion length in the affected tissues contribute to earlier age of disease onset and worsen the progression and severity of the disease over time.

27 Feb 2020

MD Anderson collaborates with Denali Therapeutics to advance novel therapies for neurodegenerative diseases

The University of Texas MD Anderson Cancer Center today announced a strategic research collaboration with Denali Therapeutics Inc. to develop novel therapies for Alzheimer's and other neurodegenerative diseases.

20 Feb 2020

Fragile X syndrome-causing repeats help human neurons function, study finds

Over half of our genomes are made of repeating elements within DNA. In rare cases, these repeats can become unstable and grow in size. These repeat "expansions" cause neurodegenerative diseases such as ALS and dementia as well as learning disorders and autism in Fragile X syndrome.

17 Feb 2020

New wearable device to diagnose Alzheimer's disease

With tens of millions of people the world over being affected by dementia, and almost 80% of them suffering from Alzheimer's disease (AD), the Early Detection of Neurodegenerative diseases (Edon) is looking into a novel device to test for AD early in the process, using wearable technology. This will play a crucial role in intervening and preventing the progression of this disease, the prevalence of which has increased by almost 90% since 2000.

16 Feb 2020

Good blood supply to the brain associated with cognitive performance

Memory performance and other cognitive abilities benefit from a good blood supply to the brain. This applies in particular to people affected by a condition known as "sporadic cerebral small vessel disease".

14 Feb 2020

New study describes inflammatory reaction in lab-developed human astrocytes

Astrocytes are neural cells with many important functions in the nervous system. The inflammation of these cells occurs in brain infections and neurodegenerative disorders, a process called astrogliosis.

14 Feb 2020

Poor neuronal connectivity between two brain regions may be predictive of Alzheimer's risk

Late-onset Alzheimer's disease, the one that appears after age 65, is the most common form of this neurodegenerative disease and accounts for more than 90% of cases.

12 Feb 2020

Unexpected findings could lead to new therapeutic intervention for ALS

A therapeutic intervention for amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, could be on the horizon thanks to unexpected findings by University of Arizona researchers.

11 Feb 2020

Greater motor reserve in long-distance skiers may help postpone onset of Parkinson's disease

To better understand the relationship between physical activity and Parkinson's Disease (PD) investigators in Sweden analyzed medical records of nearly 200,000 long-distance skiers who took part in the Vasaloppet cross-country ski race.

11 Feb 2020

Research shows how the brain's immune system could be activated to improve memory

When it comes to memory, immune cells are known as the "bad cops" of the brain. But new research shows they could also be turned into "good cops" to power memory and learning.

11 Feb 2020

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

In order to provide the best medical care for newly diagnosed Parkinson's disease (PD) patients, a method of predicting their cognitive and motor progression, beyond using purely clinical parameters, would have major implications for their management.

11 Feb 2020

Seurat publishes preclinical studies of intranasal IGF-1 in rat model of migraine headaches

Seurat Therapeutics, Inc. announced today the publication of preclinical studies of its lead product candidate, intranasal insulin-like growth factor-1 (IGF-1), in a rat model of migraine headaches, in the scientific journal Brain Research.

10 Feb 2020

Researchers receive federal grant to evaluate potential imaging biomarker for Alzheimer's

Researchers at Wake Forest School of Medicine have received a five-year grant worth approximately $2.53 million from the National Institute on Aging to evaluate whether a novel brain-imaging technique can identify Alzheimer's disease in its early stages.

9 Feb 2020

Neurodegenerative Diseases News and Research

Study discovers potential new way to slow progression of Alzheimer's

Research reveals key role of a protein in rare Batten disease

Study shows how cellular filament helps neural stem cells clear damaged, clumped proteins

Scientists reveal ability to reverse Huntington's disease-causing DNA repeat mutations in the lab

MD Anderson collaborates with Denali Therapeutics to advance novel therapies for neurodegenerative diseases

Fragile X syndrome-causing repeats help human neurons function, study finds

New wearable device to diagnose Alzheimer's disease

Good blood supply to the brain associated with cognitive performance

New study describes inflammatory reaction in lab-developed human astrocytes

Poor neuronal connectivity between two brain regions may be predictive of Alzheimer's risk

Unexpected findings could lead to new therapeutic intervention for ALS

Greater motor reserve in long-distance skiers may help postpone onset of Parkinson's disease

Research shows how the brain's immune system could be activated to improve memory

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

Seurat publishes preclinical studies of intranasal IGF-1 in rat model of migraine headaches

Researchers receive federal grant to evaluate potential imaging biomarker for Alzheimer's

Collaborative research uncovers underlying rules that, when broken, contribute to ALS

New technology distinguishes between two progressive neurodegenerative diseases

Gut bacteria help regulate contraction and relaxation of colon muscles

Researchers discover fundamental mechanism that regulates gene activity in cells

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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