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Alzheimer’s disease risk gene is involved in synaptic transmission

A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility.

14 Aug 2019

Bile pigment may play an unexpected role in protecting the brain

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting brain cells from damage from oxidative stress.

From Johns Hopkins Medicine 13 Aug 2019

Antibody target implicated in neuropsychiatric symptoms of lupus discovered

Researchers have identified a specific target of antibodies that are implicated in the neuropsychiatric symptoms of lupus, according to human research published in JNeurosci.

From Society for Neuroscience 13 Aug 2019

Tissue model of Alzheimer's mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier — the normally tight border that prevents harmful molecules in the bloodstream from entering the brain.

13 Aug 2019

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons.

13 Aug 2019

Alzheimer's disease attacks brain regions responsible for wakefulness

Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold.

13 Aug 2019

Excessive daytime sleeping could be an early sign of Alzheimer’s

Excessive daytime napping often develops long before the memory problems associated with Alzheimer's disease occur. Now, researchers may have found the striking new biological explanation for this phenomenon.

12 Aug 2019

New genomic module facilitates more personalized forms of medicine

Researchers from the HSE Epilepsy Lighthouse Project and FutureNeuro, the SFI Research Centre for Chronic and Rare Neurological Diseases hosted by RCSI, have developed a new genomics module in the Irish National Epilepsy Electronic Patient Record system.

9 Aug 2019

Scientists identify group of proteins for repair of nerve fibers

Scientists at the German Center for Neurodegenerative Diseases have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron.

7 Aug 2019

Statement related to data inaccuracies with newly approved gene therapy

As a public health agency, we believe that it is critical to facilitate the development of innovative safe and effective medical products, like the cellular and gene therapy products that have shown enormous potential to treat previously untreatable diseases.

7 Aug 2019

Alzheimers may be linked to genes that code formation of contacts between neurons

A team of neurobiologists from Peter the Great St. Petersburg Polytechnic University published an article on their study of the causes of Alzheimer's disease and suggested therapy methods.

2 Aug 2019

First-of-its-kind study in space station seeks to find causes of major diseases

High above the Earth, researchers are conducting a first-of-its-kind study to help patients with Parkinson's disease and multiple sclerosis on the planet below. The International Space Station experiment is looking for what triggers these diseases by studying how nerve and immune brain cells interact.

1 Aug 2019

Mice brain study reveals secrets about Alzheimer’s

Researchers from University of California, Irvine have found the key responses of brain cells to Alzheimer’s disease (AD) and say that this could help them understand the chronic debilitating and progressive neurodegenerative disease better in future.

1 Aug 2019

Astrocytic MORs in the hippocampus responsible for conditioned place preference

If somebody asks me "are you a coffee addict?" I may say, "Yeah it seems like, but on the one condition, only in my office." I don't have that much craving for coffee at home, but just being in the office, where I used to drink coffee all the time seeking to get caffeine jitters, seems to trigger my caffeine-addicted brain.

31 Jul 2019

Fungus used in traditional medicine could slow neuron loss in ALS

A Chinese caterpillar fungus that is used in traditional Chinese medicine has been found to minimize motor neuron loss in mice models of ALS.

25 Jul 2019

Researchers decode factors that contribute to risk of developing motor neuron disease

Trinity College Dublin researchers have found that one in 347 men and one in 436 women can be expected to develop motor neuron disease during their lifetime.

25 Jul 2019

Researchers turn to single-cell analysis to understand a pediatric brain tumor

Investigators at St. Jude Children's Research Hospital and Massachusetts General Hospital, alongside others, have revealed the cells of origin for specific subtypes of medulloblastoma, the most common malignant pediatric brain tumor.

25 Jul 2019

Researchers explore stem cells for answers to how fragile X syndrome develops

The lab of Yongchao Ma, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, discovered how the genetic defect in fragile X syndrome – a type of autism – delays production of neurons (nerve cells) at a critical time in the embryo's brain development.

24 Jul 2019

Brain protein mutation from an autistic person alters behavior in mice

A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

24 Jul 2019

Gene mutation in the brain of autism patients alters behaviors in mice

Autism spectrum disorder (ASD) has a wide range of possible causes, including genetics and environmental factors. Now, a new study suggests that a brain protein mutation may shed light on the mechanism of neurological and developmental illness.

23 Jul 2019