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New trial finds signs of preventive cardiovascular effects for cocoa flavanols

The first large-scale trial to test the long-term effects of a cocoa flavanol supplement to prevent cardiovascular disease offers promising signals that cocoa flavanols could have protective cardiovascular effects.

16 Mar 2022

Antimicrobial prescribing among infants may be prevented using maternal RSV vaccines

RSV is a leading cause of severe acute lower respiratory tract infections (LRTIs) among infants globally, and a prominent contributor to common non-severe infections that account for high volumes of antibiotic consumption.

14 Mar 2022

Ribociclib plus endocrine therapy offers survival benefit for postmenopausal patients with metastatic breast cancer

A study led by researchers from The University of Texas MD Anderson Cancer Center showed a significant overall survival benefit with ribociclib plus endocrine therapy for postmenopausal patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer.

10 Mar 2022

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

10 Mar 2022

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

The new drug nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled phase 3 clinical trial published in the New England Journal of Medicine.

9 Mar 2022

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Pancreatic cancer is one of the most aggressive and deadly tumor types and notorious for its resistance to virtually all types of treatment, including newer immunotherapies.

7 Mar 2022

Pilot study opens the door to a promising new therapeutic alternative for PTSD patients

PTSD, or post-traumatic stress disorder, doesn't discriminate. It affects about 15 million adults in the U.S. each year.

4 Mar 2022

Combination treatment could benefit smokers who also drink heavily

One in five people who smoke also drink heavily, but they show worse outcomes than non-heavy drinkers in quitting smoking and are often excluded from smoking cessation trials.

4 Mar 2022

Long-acting monoclonal antibody shows potential to offer RSV protection for all infants

Nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled Phase 3 clinical trial.

3 Mar 2022

Clinical trial report endorses nitazoxanide as a safe drug for moderately ill COVID-19 patients

Researchers tested the safety and efficacy of 600 mg oral dose of nitazoxanide in mild or moderately ill COVID-19 patients.

3 Mar 2022

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Nicotinamide riboside (NR) is amember of the vitamin B3 family, which can be found in foods like fruits, vegetables, meat, and milk. It is also used as a nutritional supplement to boost cellular levels of NAD (nicotinamide adenine dinucleotide).

2 Mar 2022

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced positive top-line results from the Phase 2 part of the Phase 2/3 study of once-daily oral RHB-107 (upamostat) in non-hospitalized symptomatic COVID-19 patients, predominantly conducted in the U.S. (60/61 patients) as well as South Africa.

1 Mar 2022

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

Researchers at Massachusetts General Hospital, in partnership with NYU Langone Health, have launched a multi-center clinical trial to investigate a new treatment for pediatric type 1 diabetes even in subjects with established disease.

1 Mar 2022

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

University of Utah Health researchers are leading a five-year, $22-million nationwide clinical trial for NMDA receptor encephalitis––a type of autoimmune encephalitis that prompts the immune system to mistakenly attack the brain, causing confusion, memory loss, seizures, and symptoms similar to bipolar disorder and other psychiatric conditions.

1 Mar 2022

First platform trial for ALS hopes to accelerate the development of effective treatments

A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial– the first platform trial for amyotrophic lateral sclerosis (ALS) designed to accelerate the development of effective and breakthrough treatments for people with the illness.

28 Feb 2022

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

Antibiotics provide no benefit in preventing future recurrent wheezing in babies hospitalized with respiratory syncytial virus (RSV), according to a new study led by Washington University School of Medicine in St. Louis. And there is some evidence that antibiotics may make wheezing worse.

27 Feb 2022

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Insilico Medicine, an end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that it has dosed multiple healthy volunteers in Phase I clinical trial evaluating ISM001-055, the first anti-fibrotic small molecule inhibitor generated by Insilico's AI-powered drug discovery platform for idiopathic pulmonary fibrosis (IPF).

24 Feb 2022

Why pregnant people were left behind while vaccines moved at ‘warp speed’ to help the masses

Kia Slade was seven months pregnant, unvaccinated, and fighting for breath, her oxygen levels plummeting, when her son came into the world last May.

24 Feb 2022

Study reveals the various ways patients with multiple sclerosis acquire disability

A new study conducted by researchers from the Corrine Goldsmith Dickinson Center for Multiple Sclerosis at Icahn School of Medicine at Mount Sinai in collaboration with Novartis, the University of Oxford and key MS experts across the globe, has revealed detailed information on the various ways patients with multiple sclerosis (MS) acquire disability.

23 Feb 2022

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

A new drug, administered in combination with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer, according to a trial published in The New England Journal of Medicine.

23 Feb 2022

Placebo News and Research

New trial finds signs of preventive cardiovascular effects for cocoa flavanols

Antimicrobial prescribing among infants may be prevented using maternal RSV vaccines

Ribociclib plus endocrine therapy offers survival benefit for postmenopausal patients with metastatic breast cancer

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Pilot study opens the door to a promising new therapeutic alternative for PTSD patients

Combination treatment could benefit smokers who also drink heavily

Long-acting monoclonal antibody shows potential to offer RSV protection for all infants

Clinical trial report endorses nitazoxanide as a safe drug for moderately ill COVID-19 patients

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

Researchers launch a multi-center trial to investigate new treatment for pediatric type 1 diabetes

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

First platform trial for ALS hopes to accelerate the development of effective treatments

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Why pregnant people were left behind while vaccines moved at ‘warp speed’ to help the masses

Study reveals the various ways patients with multiple sclerosis acquire disability

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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