Protein C News and Research

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‘Entry Point’ enzyme for COVID-19 higher in COPD patients and smokers

News-Medical speaks to Professor Don Sin on his research into COVID-19 and its effect on smokers and people suffering from COPD.

9 Apr 2020

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas.

9 Apr 2020

Discovery of key protein may lead to more effective treatments for depression

Depression is a common psychiatric disorder and one of the leading causes of disability worldwide. Antidepressants are the first-line treatment for moderate to severe major depressive episodes.

9 Apr 2020

Researchers discover novel role for dopamine that impacts gene expression related to cocaine abuse

A new role for dopamine independent of classic neurotransmission may be critical gene expression changes related to cocaine use.

9 Apr 2020

Novel coronavirus targets specific secretory cells in the lungs

Viruses attack specific host cells, which can cause chaos in the body. The novel coronavirus, now called severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 for short, infects respiratory epithelial cells in the lining of the lung, causing difficulty of breathing. The usual cause of death of those who contract the virus is pneumonia and acute respiratory distress syndrome (ARDS). Now, a new study has found that SARS-CoV-2 specifically attack certain progenitor cells called bronchial transient secretory cells in the lungs.

9 Apr 2020

Structural protein may be new target for diagnosis, treatment of depression

Scientists have zeroed in on a structural protein as a new target for the diagnosis and treatment of depression, according to research recently published in JNeurosci.

9 Apr 2020

PIV5-based MERS vaccine shows promise for COVID-19

The coronavirus disease (COVID-19) has spread to 184 countries and territories. Currently, there is no vaccine available for COVID-19 disease, or SARS-CoV-2 infection. However, scientists around the world are racing to find ways to block the virus.

8 Apr 2020

MBI may give important clues about early stages of dementia

In recent years, scientists have conducted more than 100 clinical trials in the hopes of finding new indicators capable of diagnosing Alzheimer's disease prior to the manifestation of clinical symptoms such as memory loss.

8 Apr 2020

Study reveals the coronavirus camouflage that will aid vaccine design

Research led by the University of Southampton has revealed the fundamental features of the SARS-CoV-2 coronavirus that causes COVID19.

8 Apr 2020

World's largest protein connection map reveals cell workings

The human body is comprised of billions of cells. Yet it functions and grows as a single organism, because of trillions of interactions that help various cells recognize and respond to each other via different molecules on their surface or inside the cells. Now, a new study published in the journal Nature in April 2020 describes the first-ever interactome map, to help distinguish healthy interactions and disease-producing ones.

8 Apr 2020

Exploring mechanisms of resistance to HIV in people with sickle cell disease

Analysis supports reports that sickle cell disease causes lower HIV infection rate, but cell studies did not reveal a mechanism.

8 Apr 2020

Cancer-causing mutation also promotes inflammation

Analyses of cell signals provide insight into the origin of severe inflammatory symptoms that appear in various types of blood cancer and point to possible therapeutic approaches: In around one-fourth of patients suffering from juvenile myelomonocytic leukemia, there is evidence of mutations in the so-called KRAS gene in the leukemia cells.

8 Apr 2020

Advance in understanding actin sheds light on cell function

Scientists have discovered more about actin, a chemical modification on one of the most abundant and important proteins.

8 Apr 2020

Combining Improved Ion Usage Efficiency with Data Independent Acquisition to Quantify Proteomes

In this interview, Dr. Ben Collins, Reader from the School of Biological Sciences, Queen’s University Belfast talks to News-Medical Life Sciences about his research and work into diaPASEF workflow.

From Bruker Daltonics 8 Apr 2020

World's largest map of protein connections holds clues to health and disease

Scientists have described the first reference map of interactions between gene-encoded proteins which make up cells.

8 Apr 2020

New anti-COVID-19 system could potentially fight other viruses

The ongoing COVID-19 pandemic has sparked many research projects to meet the challenge of the virus and come up with measures to fight its activity. A new study published in the journal Cell Host & Microbe in April 2020 describes a novel system to help scientists understand the virus, including mutations, diagnose infections, and also to develop and evaluate vaccines more quickly.

8 Apr 2020

Researchers discover inflammatory mechanism that contributes to autoimmune diseases

The protein STING (Stimulator of Interferon Genes) is a critical component of the body's innate immune defence system, but can also contribute to chronic autoimmune and autoinflammatory diseases.

8 Apr 2020

Active support for stem cell research is key to alleviate incurable chronic diseases

Never in modern history has the need for medical research been clearer, with COVID-19 roaring just outside our windows.

8 Apr 2020

Scientists in the UK look to measure COVID-19 in the wider community

The coronavirus disease (COVID-19) is actively spreading throughout the globe, affecting 184 countries and territories. In the United Kingdom, the country has seen the highest daily numbers of recorded coronavirus deaths – 854 on Monday and 786 on Tuesday, prompting scientists to race toward determining how vast the virus is spreading in the UK.

8 Apr 2020

Smokers need to quit during coronavirus pandemic

Smoking tobacco may aggravate the effects of coronavirus disease (COVID-19). Health experts are urging smokers to quit and cigarette companies to stop producing tobacco products to help alleviate the risks of COVID-19. A new study from China highlights the risk of smoking during the coronavirus pandemic.

7 Apr 2020