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New vaccine candidate for Zika virus proves to be effective in mice and monkeys

Researchers at the University of Hawaii medical school have successfully developed a vaccine candidate for the Zika virus, showing that it is effective in protecting both mice and monkeys from the infection.

5 Dec 2018

Study identifies new potential target for treating major common diseases

There is a large, untapped potential for developing drugs against cancer, fibrosis and cardiovascular diseases by targeting a family of receptors known as Frizzleds, researchers at Karolinska Institutet in Sweden believe. In a new study published in Science Signaling, they identify how these receptors are activated in the cell membrane and the processes that are then triggered within the cell.

4 Dec 2018

Advances in gene therapy for inherited blood disorders

Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.

4 Dec 2018

Proton pump inhibitors in combination with oral anticoagulants reduce GI bleeding risk

A Vanderbilt University Medical Centerstudy published today in JAMA shows that patients already at higher risk for gastrointestinal bleeding gain a marked protection from this risk when they take a proton pump inhibitor in combination with an oral anticoagulant.

4 Dec 2018

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

Russian researchers announced the development of a combined action drug based on ionizing radiation and bacterial toxin. Their total effect appeared to be 2,200 times stronger compared to that exerted by the radiation and toxin, separately.

4 Dec 2018

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

World AIDS Day: FIRS highlights need to strengthen efforts to stop TB and HIV

Tuberculosis is the world’s leading infectious disease and it accounts for one in three deaths from HIV/AIDS, according to the World Health Organization’s 2018 report on TB.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

A new article published today in The Lancet Oncology shows 39 percent of large B cell lymphoma patients treated with the chimeric antigen receptor T-cell therapy Yescarta remained in remission more than two years following therapy, and more than half of the patients treated remain alive.

4 Dec 2018

ACR and NPF release joint treatment guideline for psoriatic arthritis

The American College of Rheumatology and National Psoriasis Foundation have released a joint treatment guideline for psoriatic arthritis that provides evidence-based pharmacologic and non-pharmacologic recommendations on caring for treatment-naïve patients with active PsA and patients who continue to have active PsA despite treatment.

4 Dec 2018

Oral drug used to treat blood clots in cancer patients appears to be safe and effective

Mayo Clinic researchers have found that an oral drug, apixaban, used to treat blood clots in patients undergoing cancer therapy, is safe and effective.

4 Dec 2018

Rural children with mild head injuries pay more for medical care and get less of it

Families of rural children with mild head injuries pay more for medical care and get less of it, a Washington State University analysis has found.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common.

3 Dec 2018

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

Chimeric antigen receptor T-cell therapy, or CAR T, was named the 2017 Advance of the Year by the American Society of Clinical Oncology. The FDA approved two CAR T products last year for treatment of adult large B-cell lymphoma based on the exceptional patient outcomes seen in clinical trials.

3 Dec 2018

UK scientists find new way to identify patients with aggressive lymphoma

UK scientists have found a new way to identify people with the most aggressive types of lymphoma who are less likely to respond to standard drugs.

3 Dec 2018

Increasing mental health problems related to drug use in over 55's

Reports have shown that individuals aged over 45 years are increasingly being admitted to hospitals with mental health problems related to drug use. The number of admissions due to mental health problems and behavioural problems associated with drug use, were 638 in 2007/8 and have now come to 1,182 says the report.

3 Dec 2018

Very low calorie diet for type 2 diabetes to be prescribed

General Practitioners in England would soon prescribe a very low calorie diet (VLCD) for patients with type 2 diabetes in England as part of an attempt to reverse the increasingly growing numbers of the disease.

3 Dec 2018

Therapy News and Research

New vaccine candidate for Zika virus proves to be effective in mice and monkeys

Study identifies new potential target for treating major common diseases

Advances in gene therapy for inherited blood disorders

Proton pump inhibitors in combination with oral anticoagulants reduce GI bleeding risk

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

World AIDS Day: FIRS highlights need to strengthen efforts to stop TB and HIV

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

International study increases group of lung cancer patients who may benefit from immunotherapy

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

ACR and NPF release joint treatment guideline for psoriatic arthritis

Oral drug used to treat blood clots in cancer patients appears to be safe and effective

Rural children with mild head injuries pay more for medical care and get less of it

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

New strategies may improve performance of CAR-T cell therapy in treating cancer

New gene therapy treatment for Sickle Cell Anemia reverses symptoms in adults

Study shows outcomes of CAR T-cell therapy when used as standard of care for lymphoma

UK scientists find new way to identify patients with aggressive lymphoma

Increasing mental health problems related to drug use in over 55's

Very low calorie diet for type 2 diabetes to be prescribed

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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