Protein C News and Research

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Size of tumor tissue area crucial for reliable cancer prognosis, study shows

The method of choice used for preparing tissue samples can lead to biased results in the analysis of cancer patient survival.

27 Mar 2020

SLAC structural biologist discovers a strange cavity in key tuberculosis protein

Researchers from the Department of Energy’s SLAC National Accelerator Laboratory have discovered a strange new feature of a protein that’s thought to be important in the development of tuberculosis: The protein contains a “huge” interior pocket, the likes of which has never before been seen, that appears capable of passing a wide range of other molecules into the bacterial cell.

27 Mar 2020

A promising strategy to overcome drug resistance developed by blood cancer cells

In a collaborative study published in Blood Advances, a research group led by Beate Heissig at Juntendo University and Yousef Salama at An Najah University report a strategy to overcome drug resistance developed by blood cancer cells.

27 Mar 2020

Global scientific collaboration produces first genetic map of the cerebral cortex

The cerebral cortex is the relatively thin, folded, outer "gray matter" layer of the brain crucial for thinking, information processing, memory, and attention.

27 Mar 2020

Targeting specific histone deacetylase may be novel therapeutic strategy for NSCLC

The survival rates for patients with non-small cell lung cancer have improved greatly over the past decade thanks to several new targeted treatment options for patients.

26 Mar 2020

Mount Sinai researchers reveal innovative mechanisms to predict and prevent Crohn's disease

In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD.

26 Mar 2020

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults.

26 Mar 2020

Anteater-like animals are the missing link for coronavirus transmission between bats and humans

As scientists scramble to learn more about the SARS-CoV-2 coronavirus, two recent studies of the virus' genome reached controversial conclusions: namely, that snakes are intermediate hosts of the new virus, and that a key coronavirus protein shares "uncanny similarities" with an HIV-1 protein.

26 Mar 2020

Scientists unravel mystery about how nature can access genetic information in cells

Australian scientists have unraveled part of the mystery about how nature can usefully access genetic information in cells despite it being so tightly packed away.

26 Mar 2020

Insights into diagnosis and treatment of rare pediatric brain cancer

Ependymoma is a rare form of brain cancer that implicates children and is often tricky to diagnose.

26 Mar 2020

Model that sheds light on severe Duchenne muscular dystrophy could pave the way for new therapies

Researchers have developed an experimental model of severe Duchenne muscular dystrophy that offers insight into the disease.

26 Mar 2020

Key protein in sperm production could aid male infertility treatments

Researchers have discovered that a key protein drives sperm production, knowledge that may help infertile couples conceive.

26 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Targeting critical enzyme for sperm formation could help address male infertility

While some of our body's cells divide in a matter of hours, the process of making sperm, meiosis, alone takes about 14 days from start to finish. And fully six of those days are spent in the stage known as the pachytene, when pairs of chromosomes from an individual's mother and father align and connect.

25 Mar 2020

Researchers aim to find the genetic basis of severe coronavirus infection in young people

Hundreds of clinicians worldwide are banding together in an effort to study some types of severe cases of the new coronavirus disease.

25 Mar 2020

Overexpression of hPCL3S could contribute to tumor progression in prostate cancer

The cover for issue 12 of Oncotarget features Figure 11, "Global analyses of the RNA-Seq data of LNCaP empty vector and LNCaP cells overexpressing hPCL3S (Clone 12)" by Abdelfettah, et al.

25 Mar 2020

A genetic toolkit to produce multifunctional magnetic nanoparticles

Magnetic bacteria might soon be used for the production of novel biomaterials. A team of microbiologists at the University of Bayreuth led by Prof. Dr. Dirk Schüler developed a modular system for the genetic reprogramming of bacteria, thereby turning the organisms into cell factories for multifunctional magnetic nanoparticles that combine various useful functions and properties.

25 Mar 2020

Diet, nutrition have profound impact on microbial composition in the gut

Nutrition and diet have a profound impact on microbial composition in the gut, in turn affecting a range of metabolic, hormonal, and neurological processes, according to a literature review by scientists from the George Washington University and the National Institute of Standards and Technology.

25 Mar 2020

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Treating T cells harvested from a patient with a combination of an epigenetic drug and a cytokine while expanding the cells in the lab re-programs them into a stronger T cell type that persists longer than its comrades, researchers at The University of Texas MD Anderson Cancer Center report in Cancer Immunology Research, a journal of the American Association for Cancer Research.

25 Mar 2020

Mapping the cannabis genome to improve agriculture and human health

Unlocking the full potential of cannabis for agriculture and human health will require a co-ordinated scientific effort to assemble and map the cannabis genome, says a just-published international study led by University of Saskatchewan researchers.

25 Mar 2020

Protein C News and Research

Size of tumor tissue area crucial for reliable cancer prognosis, study shows

SLAC structural biologist discovers a strange cavity in key tuberculosis protein

A promising strategy to overcome drug resistance developed by blood cancer cells

Global scientific collaboration produces first genetic map of the cerebral cortex

Targeting specific histone deacetylase may be novel therapeutic strategy for NSCLC

Mount Sinai researchers reveal innovative mechanisms to predict and prevent Crohn's disease

New 'more effective' stem cell transplant method could improve treatment of blood diseases

Anteater-like animals are the missing link for coronavirus transmission between bats and humans

Scientists unravel mystery about how nature can access genetic information in cells

Insights into diagnosis and treatment of rare pediatric brain cancer

Model that sheds light on severe Duchenne muscular dystrophy could pave the way for new therapies

Key protein in sperm production could aid male infertility treatments

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Targeting critical enzyme for sperm formation could help address male infertility

Researchers aim to find the genetic basis of severe coronavirus infection in young people

Overexpression of hPCL3S could contribute to tumor progression in prostate cancer

A genetic toolkit to produce multifunctional magnetic nanoparticles

Diet, nutrition have profound impact on microbial composition in the gut

Combination produces more proliferative, enduring central memory T cells for cellular therapy

Mapping the cannabis genome to improve agriculture and human health

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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