Antibiotic Resistance News and Research

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Nanosponge vaccine blocks adverse effects of alpha-haemolysin toxin from MRSA

Nanosponges that soak up a dangerous pore-forming toxin produced by MRSA (methicillin-resistant Staphylococcus aureus) could serve as a safe and effective vaccine against this toxin. This "nanosponge vaccine" enabled the immune systems of mice to block the adverse effects of the alpha-haemolysin toxin from MRSA-both within the bloodstream and on the skin. Nanoengineers from the University of California, San Diego described the safety and efficacy of this nanosponge vaccine in the December 1 issue of Nature Nanotechnology.

2 Dec 2013

UC San Diego biophysicists discover how antibiotic resistance allows bacteria to multiply

Using quantitative models of bacterial growth, a team of UC San Diego biophysicists has discovered the bizarre way by which antibiotic resistance allows bacteria to multiply in the presence of antibiotics, a growing health problem in hospitals and nursing homes across the United States.

30 Nov 2013

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

During Antibiotic Awareness Week (18-24 November) NPS MedicineWise is urging health professionals to use vaccinations as one important way to limit Australia’s use of antibiotics.

22 Nov 2013

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

During Antibiotic Awareness Week (18-24 November) NPS MedicineWise is urging health professionals to use vaccinations as one important way to limit Australia’s use of antibiotics.

22 Nov 2013

Antibiotic resistance holds stable in U.S. children's hospitals

Two studies published in the December issue of Infection Control and Hospital Epidemiology show antibiotic resistance patterns for children have held stable over a seven-year period and surgical patients in U.S. children's hospitals account for 43 percent of all antibiotic use in children's hospitals, presenting an opportunity for targeted intervention.

21 Nov 2013

Rapid DNA biochip tests for screening disease-causing bacteria

Patients affected by a bacterial infection can usually be treated with an antibiotic. But sometimes a resistant bacterial strain is causing the infection. In a hospital setting, doctors ideally want to know if they are dealing with such bacteria and which drugs they should choose. But if the doctor runs a test it can take days to get a result. Now, a European project is paving the way for much more rapid tests using DNA biochips. The aim is to rapidly screen disease-causing bacteria using a microarray to spot which resistant genes are present in bacteria.

20 Nov 2013

NPS MedicineWise urges people to guard against superbug whilst travelling

With the holiday season just around the corner and many Australians heading overseas, NPS MedicineWise is urging people to guard against the risk of infection whilst travelling.

20 Nov 2013

Study shows bacteria can passively integrate damaged DNA in their own genome

From a bacteria's perspective the environment is one big DNA waste yard. Researchers have now shown that bacteria can take up small as well as large pieces of old DNA from this scrapheap and include it in their own genome.

20 Nov 2013

Entire structure of health-care delivery needs to be re-engineered to address threat of antibiotic resistance

The entire structure of health-care delivery for effective antibiotics – from research and development, to distribution and rational use – needs to be re-engineered to address the looming global threat of antibiotic resistance, say the authors of a new report, published today [Sunday 17 November] in The Lancet Infectious Diseases, ahead of European Antibiotic Awareness Day, and the US Centers for Disease Control and Prevention (CDC) ‘Get Smart About Antibiotics Week’ on Monday 18 November.

18 Nov 2013

NPS MedicineWise urges all health professionals to preserve the miracle of antibiotics

Marking the start of Antibiotic Awareness Week, NPS MedicineWise is urging all health professionals to pledge their commitment to preserve the miracle of antibiotics and re-shape consumer expectations of these lifesavings medicines.

18 Nov 2013

Friendly microbes in the guts of healthy children have numerous antibiotic resistance genes

Friendly microbes in the intestinal tracts (guts) of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists at Washington University School of Medicine in St. Louis.

14 Nov 2013

Diagnostic technology advancing but barriers prevent integration into care, IDSA report warns

Despite advances in diagnostic technology, there is an urgent need for tests that are easy to use, identify the bug causing an infection and provide results faster than current tests, according to a report from the Infectious Diseases Society of America published today in a special supplement to Clinical Infectious Diseases.

7 Nov 2013

FDA issues GRAS Letters of No Objection for Morinaga's proprietary probiotic strain

Morinaga Milk Industry Co., Ltd., the second largest dairy product company in Japan, today announced that the U.S. Food and Drug Administration has issued Generally Recognized as Safe Letters of No Objection for Morinaga's proprietary probiotic strain, Bifidobacterium breve M-16V for food applications and infant formulas.

6 Nov 2013

Identifying gaps in infection prevention practices may help improve patient safety, shows study

Identifying gaps in infection prevention practices may yield opportunities for improved patient safety, according to a survey published in the November issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

30 Oct 2013

Researchers develop new substance that quickly and effectively kills multi-resistant bacteria

In Europe alone, more than 25,000 people die each year from infections caused by multi-resistant bacteria. Researchers from University of Copenhagen have now developed and characterized a substance that quickly and effectively kills the virulent bacteria. The substance employs a multifunctional mechanism that reduces the risk of antibiotic resistance. The findings have recently been published in the scientific journal Chemistry & Biology.

30 Oct 2013

Queen's University is lead partner in £6M global research program to develop new ways to treat CF

Queen's University Belfast is a lead partner in a new -6 million (euro) global research programme to develop new ways to treat Cystic Fibrosis.

30 Oct 2013

AmpliPhi, University of Leicester partner to develop novel bacteriophage therapy against C. difficile

AmpliPhi BioSciences Corporation, the leader in the development of bacteriophage-based antibacterial therapies to treat antibiotic resistant infections, announces it has entered into Collaboration and License Agreements with UK-based University of Leicester to develop a novel bacteriophage therapy targeting Clostridium difficile, a serious gastrointestinal infection for which new treatments are urgently required.

17 Oct 2013

King's College researchers identify new biomarker that detects sepsis in blood

Researchers at King's College London have identified a biomarker - a biological 'fingerprint' - for sepsis in the blood, and showed it could be possible to diagnose the condition within two hours by screening for this biomarker at a patient's bedside.

17 Oct 2013

New type of antibiotic kills multidrug-resistant germ common to health care settings

A new type of antibiotic called a PPMO, which works by blocking genes essential for bacterial reproduction, successfully killed a multidrug-resistant germ common to health care settings, UT Southwestern Medical Center researchers report.

16 Oct 2013

University of Sydney's free public talk to focus on halting superbug apocalypse

Everyday activities such as kissing, touching and sharing food can lead to the spread of a new kind of superbug that is as dangerous as it is resistant.

15 Oct 2013

Antibiotic Resistance News and Research

Nanosponge vaccine blocks adverse effects of alpha-haemolysin toxin from MRSA

UC San Diego biophysicists discover how antibiotic resistance allows bacteria to multiply

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

New NPS Direct article reveals that vaccinations fight against antibiotic resistance

Antibiotic resistance holds stable in U.S. children's hospitals

Rapid DNA biochip tests for screening disease-causing bacteria

NPS MedicineWise urges people to guard against superbug whilst travelling

Study shows bacteria can passively integrate damaged DNA in their own genome

Entire structure of health-care delivery needs to be re-engineered to address threat of antibiotic resistance

NPS MedicineWise urges all health professionals to preserve the miracle of antibiotics

Friendly microbes in the guts of healthy children have numerous antibiotic resistance genes

Diagnostic technology advancing but barriers prevent integration into care, IDSA report warns

FDA issues GRAS Letters of No Objection for Morinaga's proprietary probiotic strain

Identifying gaps in infection prevention practices may help improve patient safety, shows study

Researchers develop new substance that quickly and effectively kills multi-resistant bacteria

Queen's University is lead partner in £6M global research program to develop new ways to treat CF

AmpliPhi, University of Leicester partner to develop novel bacteriophage therapy against C. difficile

King's College researchers identify new biomarker that detects sepsis in blood

New type of antibiotic kills multidrug-resistant germ common to health care settings

University of Sydney's free public talk to focus on halting superbug apocalypse

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