Antigen News and Research

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Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Most research on immunity to the SARS-CoV-2 virus and COVID-19 vaccine development has focused on antibody responses to the spike protein and other viral surface proteins.

24 Jun 2022

Natural and hybrid immunity dynamics in South African mothers

Researchers evaluated natural and hybrid immunity after four COVID-19 waves in South Africa.

24 Jun 2022

Associations between maternal COVID-19 vaccination and hospitalization among infants

Researchers assessed the efficacy of maternal mRNA vaccinations during pregnancy against hospitalization for COVID-19 in infants aged <6 months.

24 Jun 2022

Characterization of SARS-CoV-2 Omicron persistence and infectivity among children

Researchers characterized the persistence and infectivity of SARS-CoV-2 Omicron among children.

24 Jun 2022

Epstein-Barr virus can reactivate in long COVID

In a recent study posted to the medRxiv* preprint server, researchers at the University of California, San Francisco, and Monogram Biosciences examined the connections between the post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) and Epstein-Barr virus (EBV) reactivation.

23 Jun 2022

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

A recent article posted to the bioRxiv* preprint server identified numerous efficacious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from convalescent SARS-CoV-2 patients.

23 Jun 2022

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Colorectal, pancreatic, esophageal and stomach cancers - some of the deadliest kinds of cancer - have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment.

23 Jun 2022

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Researchers investigated a highly variable region at residues 203 to 205 in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein.

23 Jun 2022

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

A recent work posted to the bioRxiv* preprint server assessed the indicators of anamnestic humoral immunity among the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

23 Jun 2022

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Jun 2022

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T–cell therapy for treatment of solid tumors.

22 Jun 2022

COVID-19 outcomes improved for SARDs patients through Omicron wave

In a recent study posted to the medRxiv* pre-print server, researchers investigated coronavirus disease 2019 (COVID-19) incidence and severity among systemic autoimmune rheumatic diseases (SARDs) patients in Massachusetts, United States (US), between March 1, 2020, and January 31, 2022.

22 Jun 2022

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

A recent study published in the Cell Reports journal analyzed immune ecology at the placenta in mild or asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy.

22 Jun 2022

New screening tool could increase the number of tests on solid tumor sample by up to 50 times

A screening tool developed at the University of Strathclyde, UK, could increase the number of tests on a solid tumor sample by up to 50 times.

21 Jun 2022

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

21 Jun 2022

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

A recent article under review at the Nature Portfolio journal and currently available on the Research Square* preprint server analyzed the factors influencing the durability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitope-specific T cell reaction.

21 Jun 2022

Researchers assess monkeypox clinical management guidelines worldwide

A new study demonstrated the scarcity of appropriate clinical management guidelines for monkeypox infections across the globe.

20 Jun 2022

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

In a recent study posted to the medRxiv* preprint server, researchers explored the association between circulating coronavirus disease 2019 (COVID-19) antigens and post-COVID-19 sequelae (long COVID).

20 Jun 2022

How effective are mRNA COVID-19 vaccine boosters against Omicron?

In a recent study posted to the medRxiv* preprint server, researchers University of Washington, University of Michigan, Duke University, and Veterans Affairs Portland Healthcare System assessed the effectiveness of the coronavirus disease 2019 (COVID-19) booster vaccines.

19 Jun 2022

Long-COVID risk reduced with Omicron versus Delta

In a recent study published in The Lancet, researchers at King's College London and ZOE Limited assessed the risk of long coronavirus disease (COVID) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants in the United Kingdom (UK).

19 Jun 2022

Antigen News and Research

Antibody profiles of internal viral proteins predict severe COVID-19 outcomes

Natural and hybrid immunity dynamics in South African mothers

Associations between maternal COVID-19 vaccination and hospitalization among infants

Characterization of SARS-CoV-2 Omicron persistence and infectivity among children

Epstein-Barr virus can reactivate in long COVID

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Listeria-based booster vaccine strategy offers improved protection against recurrent colorectal cancer

Mutation in SARS-CoV-2 nucleocapsid protein found to enhance replication and pathogenicity

Correlates of anamnestic humoral immunity throughout SARS-CoV-2 variants of concern

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

Preclinical study unlocks the promise of CAR T-cell therapy for treatment of solid tumors

COVID-19 outcomes improved for SARDs patients through Omicron wave

Even asymptomatic maternal COVID-19 can potentially cause pregnancy complications

New screening tool could increase the number of tests on solid tumor sample by up to 50 times

Wistar scientists discover a new way to boost a person's immune response to tumors

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

Researchers assess monkeypox clinical management guidelines worldwide

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

How effective are mRNA COVID-19 vaccine boosters against Omicron?

Long-COVID risk reduced with Omicron versus Delta

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