Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Scientists use machine learning to unveil new predictors of post-menopausal breast cancer

Researchers identify five novel correlations with post-menopausal breast cancer including urine biomarkers, blood counts, and blood biochemistry.

11 Jun 2023

Combining blood biomarkers with genomics could provide useful information about disease risk

Being to identify people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick.

9 Jun 2023

An overview of the relationship between the exposome and cardiovascular health

Researchers discussed the association between cardiovascular health and the exposome.

8 Jun 2023

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "DNAmFitAge: biological age indicator incorporating physical fitness."

7 Jun 2023

Ancient, virus-like protein may contribute to ALS

More than 5,000 people are diagnosed annually with ALS (amyotrophic lateral sclerosis), a fatal, neurodegenerative disease that attacks nerve cells in the brain and spinal cord, gradually robbing people of the ability to speak, move, eat and breathe.

7 Jun 2023

Experts investigate the correlation between BORIS mutations and protein expression

A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, "Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression."

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Simple blood test for the diagnosis of Glut1 deficiency syndrome

Glut1 deficiency syndrome is a rare and disabling neurological disease still relatively unknown to the medical community.

5 Jun 2023

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Three clinical trials led by researchers at The University of Texas MD Anderson Cancer Center demonstrated positive results from the targeted therapy erdafitinib for patients with multiple tumor types harboring FGFR alterations.

5 Jun 2023

Flavanol consumption improves hippocampal memory function associated with cognitive aging

Researchers investigated the impact of dietary flavanols on cognitive aging.

5 Jun 2023

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

At the 2023 American Society for Clinical Oncology Annual Meeting—to be held June 2-6 in Chicago, Illinois—Fred Hutchinson Cancer Center experts will present research spanning survivorship, advances in treatments and clinical trials, how access to cancer care affects outcomes, integrative medicine and more.

5 Jun 2023

Study finds improved survival in patients with SLE-associated PAH

A team from Peking Union Medical College Hospital in Beijing, China, have explored changes in the characteristics, treatment, and 5-year survival for SLE-associated PAH in the last decade, and possible reasons for survival change.

2 Jun 2023

University of Louisville researchers receive $5.8 million to prevent immune system dysregulation

Researchers at the University of Louisville have received $5.8 million in two grants from the National Institutes of Health to expand their work to better understand and prevent immune system dysregulation responsible for acute respiratory distress, the condition responsible for serious illness and death in some COVID-19 patients.

2 Jun 2023

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Researchers evaluated the relationship between PFAS exposure during pregnancy and birth outcomes.

2 Jun 2023

Accounting for genetic factors can improve accuracy of prostate cancer screening

The accuracy of prostate-specific antigen (PSA) screening for prostate cancer can be improved by accounting for genetic factors that cause changes in PSA levels that are not associated with cancer, according to a multi-center study led by UC San Francisco and Stanford University.

1 Jun 2023

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

Scientists have identified a lipid-degrading enzyme as a prognostic biomarker for luminal breast cancer.

31 May 2023

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Evidence supports a close link between Aβ, astrocyte reactivity, and tau pathology in preclinical AD.

31 May 2023

Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

Diet low in flavanols linked to age-related memory loss

A large-scale study led by researchers at Columbia and Brigham and Women's Hospital/Harvard is the first to establish that a diet low in flavanols - nutrients found in certain fruits and vegetables - drives age-related memory loss.

29 May 2023

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

A new study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, provides a deeper understanding of the vast diversity of T cell states as well as their relationships and roles within the complex tumor microenvironment, bringing a fresh perspective to understanding immunotherapy efficacy in cancer.

29 May 2023

Biomarker News and Research

Further Reading

Scientists use machine learning to unveil new predictors of post-menopausal breast cancer

Combining blood biomarkers with genomics could provide useful information about disease risk

An overview of the relationship between the exposome and cardiovascular health

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

Ancient, virus-like protein may contribute to ALS

Experts investigate the correlation between BORIS mutations and protein expression

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Simple blood test for the diagnosis of Glut1 deficiency syndrome

Clinical trials demonstrate positive results from targeted therapy for patients with multiple tumor types with FGFR alterations

Flavanol consumption improves hippocampal memory function associated with cognitive aging

Fred Hutch experts highlight research on cancer treatment advances, survivorship and precision oncology at ASCO

Study finds improved survival in patients with SLE-associated PAH

University of Louisville researchers receive $5.8 million to prevent immune system dysregulation

To what extent does prenatal folate status modify associations between early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure and birth outcomes?

Accounting for genetic factors can improve accuracy of prostate cancer screening

Lipid-degrading enzyme, fatty acid amide hydrolase is a predictor of long-term survival in patients with breast cancer

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Obesity strikes below the belt: Study reveals link between obesity and male infertility

Diet low in flavanols linked to age-related memory loss

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo