Compound News and Research

RSS

Systematic review: The involvement of bitter taste receptors in cancer

Humans have 25 different types of functional bitter taste receptors. These are found on our tongue, where they facilitate the taste perception of bitter tasting compounds. In addition, there are increasing findings that cells of extra-oral organs also have such receptors.

4 Dec 2021

Targeting the brain should be the focus of ALS therapy, not just spinal cord

The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), Northwestern Medicine scientists have discovered.

4 Dec 2021

New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant - a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Study could lead to new strategies to prevent or slow Alzheimer's disease

A gene mutation linked to Alzheimer's disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study by scientists at Weill Cornell Medicine.

1 Dec 2021

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson's disease.

1 Dec 2021

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Researchers at Washington University School of Medicine in St. Louis have identified a drug compound that makes pancreatic cancer cells more vulnerable to chemotherapy.

1 Dec 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

Antiviral activity of a photoactivable natural product on coronaviruses

A new study showed that pheophorbide a has antiviral activity against many CoVs.

26 Nov 2021

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Researchers determine the inhibition capacity of iota-carrageenan and xylitol in three different candidate preservative-free formulations.

24 Nov 2021

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

When something disrupts hormone binding to the receptor, such as environmental compounds or pollutants, called endocrine disrupting chemicals (EDCs), the results can be harmful and, in some cases, lead to certain forms of cancer.

24 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

How does penicillin work?

In this interview, we spoke to Dr. Bartlomiej Salamaga about his latest research that discovered how penicillin works in the body.

24 Nov 2021

Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19

In a study published in the journal Scientific Reports, a research group from Brazil showed how antiviral anionic phthalocyanine derivative used in a mouthwash protocol may not only reduce the symptoms of coronavirus disease (COVID-19), but also hamper the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Nov 2021

Compound News and Research

Systematic review: The involvement of bitter taste receptors in cancer

Targeting the brain should be the focus of ALS therapy, not just spinal cord

New nanoparticle adjuvant could help make vaccines more powerful

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Study could lead to new strategies to prevent or slow Alzheimer's disease

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

Researchers identify new drug that makes pancreatic cancer cells more vulnerable to chemotherapy

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Study finds atazanavir inhibits main SARS-CoV-2 protease

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

Antiviral activity of a photoactivable natural product on coronaviruses

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Novel method enables deeper analysis of endocrine disrupting chemicals' impact on gene expression

Experimental compound reduces diabetic complications in mice

How does penicillin work?

Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

Researchers reveal ethical and social issues faced by healthcare workers during the pandemic

Paper-based innovations for COVID-19 diagnosis

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Latest News