Leukemia News and Research

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Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

Staggering prices slow insurers’ coverage of CAR-T cancer therapy

Patients whose blood cancers have failed to respond to repeated rounds of chemotherapy may be candidates for a new type of gene therapy that could send their cancers into remission for years.

17 Jul 2018

Researchers map family trees of cancer cells to understand how AML responds to new drug

For the first time, a team of international researchers have mapped the family trees of cancer cells in acute myeloid leukemia to understand how this blood cancer responds to a new drug, enasidenib.

17 Jul 2018

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

A review of more than 200 studies reveals that olfactory receptors--proteins that bind to odors that aid the sense of smell--perform a wide range of mostly unknown functions outside the nose.

12 Jul 2018

New findings refine link between clonal hematopoiesis and blood cancer risk

It's a common occurrence in elderly people: Blood cells carrying mutated DNA explosively increase in number, resulting in genetic "mosaicism": the presence of a population of cells that carries an altered genome.

12 Jul 2018

Researchers uncover molecular drivers of a deadly pediatric cancer

Researchers have made important discoveries about the molecular mechanisms driving acute myeloid leukemia (AML), a deadly pediatric cancer.

11 Jul 2018

Scientists discover new way to predict healthy individuals at risk of developing AML

An international team of leukemia scientists has discovered how to predict healthy individuals at risk of developing acute myeloid leukemia, an aggressive and often deadly blood cancer.

10 Jul 2018

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

CTI BioPharma Corp. and Servier today announced that the pivotal Phase III study evaluating PIXUVRI® combined with rituximab in comparison to gemcitabine combined with rituximab in patients with aggressive B-cell non-Hodgkin lymphoma did not meet its primary endpoint of improvement of progression-free survival

9 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

Human leukemia virus increases disease risk by changing the way DNA loops inside our cells

A human virus that causes a rare form of leukemia increases the risk of disease by changing the way DNA loops inside our cells.

29 Jun 2018

Researchers show how mutant CALR protein triggers cancer

Researchers at Juntendo University report in the journal Leukemia how mutants of the protein calreticulin lead to molecular mechanisms triggering myeloproliferative neoplasms, which can cause cancer. The findings may lead to the development of novel therapies for certain types of blood cancer.

28 Jun 2018

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

A Delaware team including Erin Crowgey, PhD, associate director of Bioinformatics with Nemours Biomedical Research, has published a study in the peer-reviewed journal BMC Bioinformatics, showing that DNA patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients.

22 Jun 2018

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Researchers have shown that patients with spastic cerebral palsy (CP) can be identified using DNA methylation patterns in circulating blood cells.

22 Jun 2018

UC Riverside researcher receives grants to advance cancer, ALS research

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis, and other neurodegenerative diseases.

21 Jun 2018

Leukemia News and Research

Further Reading

Staggering prices slow insurers’ coverage of CAR-T cancer therapy

Researchers map family trees of cancer cells to understand how AML responds to new drug

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

New findings refine link between clonal hematopoiesis and blood cancer risk

Researchers uncover molecular drivers of a deadly pediatric cancer

Scientists discover new way to predict healthy individuals at risk of developing AML

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Streamlining and translating basic science discoveries into the clinic

Human leukemia virus increases disease risk by changing the way DNA loops inside our cells

Researchers show how mutant CALR protein triggers cancer

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

Researchers diagnose cerebral palsy using AI and next-generation sequencing

UC Riverside researcher receives grants to advance cancer, ALS research

Harnessing Pediatric Cancer Genomic Data in the Cloud

Study tests accuracy of device designed to detect heart dysfunction in childhood cancer survivors

New guidelines recommend newborns with Down’s syndrome to receive leukemia test

New computational method identifies molecular signatures that distinguish individuals

OHSU Knight Cancer Institute Director wins 2018 Tang Prize in Biopharmaceutical Science

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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