Mitochondria News and Research

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Lafora rare disease could be aggravated by oxidative stress

Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for its disposal. Researchers at the University of Valencia have led a study in which they propose that Lafora rare disease could be aggravated by oxidative stress.

22 May 2015

Vitamin E helps build strong muscles

Body builders have it right: vitamin E does help build strong muscles, and scientists appear to have figured out one important way it does it.

19 May 2015

Study sheds light on long-hidden link between chronic high blood sugar and disruption of mitochondria

Scientists at Johns Hopkins say they've discovered a cause-and-effect link between chronic high blood sugar and disruption of mitochondria, the powerhouses that create the metabolic energy that runs living cells. The discovery, reported online in Proceedings of the National Academy of Sciences on April 27, sheds light on a long-hidden connection and, they say, could eventually lead to new ways of preventing and treating diabetes.

6 May 2015

Linkam stages used to study the effects of cryopreservation on the quality of Koala spermatozoa samples

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their temperature controlled stages in the study of the effects of cryopreservation of Koala spermatozoa in Australia.

From Linkam Scientific Instruments 28 Apr 2015

Understanding how nerve cells in the brain produce energy required to function

New research published today in the journal Nature Communications represents a potentially fundamental shift in our understanding of how nerve cells in the brain generate the energy needed to function. The study shows neurons are more independent than previously believed and this research has implications for a range of neurological disorders.

25 Apr 2015

Mitotech reports positive results from SkQ1 Phase II trial in patients with moderate to severe dry eye syndrome

Mitotech S.A, a Luxembourg-based clinical-stage biotechnology company developing novel antioxidant molecules targeting mitochondria, today announced that it has achieved significant positive results in its U.S. Phase II clinical trial of SkQ1 compound in patients with moderate to severe dry eye syndrome.

24 Apr 2015

Mitotech reports positive results from SkQ1 Phase II trial in patients with moderate to severe dry eye syndrome

24 Apr 2015

Novel findings may hold promise for children, adults with mitochondrial disorders

Rooted in malfunctions in the tiny power plants that energize our cells, mitochondrial disorders are notoriously complex and variable, with few effective treatments. Now, novel findings in microscopic worms may hold great promise for children and adults with mitochondrial disorders

16 Apr 2015

Ancient natural compound can protect the heart from hypertrophy

A natural compound derived from the bark of the magnolia tree, can protect the heart from hypertrophy, a thickening of cardiac muscle often caused by chronic high blood pressure that can lead to heart failure, researchers report in the April 14 issue of the online journal Nature Communications.

15 Apr 2015

Study may help find treatments for nerve cell damage, neurodegenerative disorders

Scientists from Kyoto University's Institute for Integrated Cell-Material Sciences in Japan have have discovered how nerve cells adjust to low energy environments during the brain's growth process.

13 Apr 2015

New automated tool rapidly delivers large particles into mammalian cells

A new device developed by UCLA engineers and doctors eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.

10 Apr 2015

Diet rich in high glucoraphanin broccoli reduces blood LDL-cholesterol levels by around 6%

Including a new broccoli variety in the diet reduces blood LDL-cholesterol levels by around 6%, according to the results of human trials led by the Institute of Food Research.

9 Apr 2015

CUMC researchers identify cellular defect that could lead to potential new treatment for diabetes

A cellular defect that can impair the body's ability to handle high glucose levels and could point the way to a potential new treatment for diabetes has been identified by Columbia University Medical Center researchers.

8 Apr 2015

Common cancers deform mitochondria to create conducive environment for tumor growth

In a breakthrough in the understanding of how cancer does its deadly work, researchers at the University of Virginia School of Medicine have shown that many cancers - including nearly all pancreatic cancers - enslave and deform mitochondria, the powerhouses of cells, to create an environment more conducive to tumor growth.

7 Apr 2015

Researchers test effects of light therapy on brain function

Following up on promising results from pilot work, researchers at the VA Boston Healthcare System are testing the effects of light therapy on brain function in veterans with Gulf War Illness.

3 Apr 2015

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

According to our understanding, mitochondria undergo cycles of fusion-fission, i.e. they divide within the constraints of a cell and, upon cell division, each of the two daughter cells gets its ‘share’ of mitochondria.

29 Mar 2015

Experimental drug that attacks brain tumor cells passes early tests

An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.

25 Mar 2015

ISSCR statement calls for moratorium nuclear genome editing of human germ line

In a statement released yesterday, the International Society for Stem Cell Research called for a moratorium on attempts at clinical application of nuclear genome editing of the human germ line to enable more extensive scientific analysis of the potential risks of genome editing and broader public discussion of the societal and ethical implications.

23 Mar 2015

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

The DNA you inherit from your parents contributes to the physical make-up of your body -- whether you have blue eyes or brown, black hair or red, or are male or female.

23 Mar 2015

Olive ingredients may prevent Alzheimer's disease

It has long been proven that people who follow a Mediterranean diet and keep physically and mentally active are less likely to suffer from dementia. Olives in particular appear to play a key role in this regard. But just what are the substances contained in these small, oval fruit that are so valuable? This is what a Hessen-based group of researchers from the Goethe University Frankfurt, the Technical University of Darmstadt and Darmstadt company N-Zyme BioTec GmbH intends to find out. The three-year project "NeurOliv" has a project volume of 1.3 million Euros and is funded by the Federal Ministry of Education and Research as part of the high-tech initiative "KMU-innovativ Biochance".

20 Mar 2015

Mitochondria News and Research

Lafora rare disease could be aggravated by oxidative stress

Vitamin E helps build strong muscles

Study sheds light on long-hidden link between chronic high blood sugar and disruption of mitochondria

Linkam stages used to study the effects of cryopreservation on the quality of Koala spermatozoa samples

Understanding how nerve cells in the brain produce energy required to function

Mitotech reports positive results from SkQ1 Phase II trial in patients with moderate to severe dry eye syndrome

Mitotech reports positive results from SkQ1 Phase II trial in patients with moderate to severe dry eye syndrome

Novel findings may hold promise for children, adults with mitochondrial disorders

Ancient natural compound can protect the heart from hypertrophy

Study may help find treatments for nerve cell damage, neurodegenerative disorders

New automated tool rapidly delivers large particles into mammalian cells

Diet rich in high glucoraphanin broccoli reduces blood LDL-cholesterol levels by around 6%

CUMC researchers identify cellular defect that could lead to potential new treatment for diabetes

Common cancers deform mitochondria to create conducive environment for tumor growth

Researchers test effects of light therapy on brain function

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

Experimental drug that attacks brain tumor cells passes early tests

ISSCR statement calls for moratorium nuclear genome editing of human germ line

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

Olive ingredients may prevent Alzheimer's disease

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