Mitochondria News and Research

RSS

Insight into male infertility

Around one in 20 men is infertile, but despite the best efforts of scientists, in many cases the underlying causes of infertility have remained a mystery.

16 May 2011

Study offers hints to why Parkinson's so selectively harms dopamine-producing cells

New data offer hints to why Parkinson's disease so selectively harms brain cells that produce the chemical dopamine, say researchers at Washington University School of Medicine in St. Louis.

13 May 2011

Researchers identify mitochondrial proteins that can affect human ageing

Mitochondria are the body's energy producers, the power stations inside our cells. Researchers at the University of Gothenburg, Sweden, have now identified a group of mitochondrial proteins, the absence of which allows other protein groups to stabilise the genome. This could delay the onset of age-related diseases and increase lifespan.

10 May 2011

Scientists discover new mitochondria regulation mechanism

Scientists have discovered a new component of mitochondria that plays a key part in their function. The discovery, which is presented in the journal Cell Metabolism, is of potential significance to our understanding of both inherited and age-related diseases.

4 May 2011

New antioxidant may prevent liver damage in chronic alcoholics

An antioxidant may prevent damage to the liver caused by excessive alcohol, according to new research from the University of Alabama at Birmingham.

3 May 2011

Stealth Peptides launches mitochondrion targeting compound Bendavia at Experimental Biology 2011

Stealth Peptides Inc., a privately held biopharmaceutical company developing innovative mitochondrial therapies, introduced its lead clinical candidate, Bendavia™, a novel compound that targets the mitochondrion, during multiple scientific sessions of the Experimental Biology 2011 meeting.

20 Apr 2011

Researchers discover new way to force cancer cells to self-destruct

Researchers at The Wistar Institute have found a new way to force cancer cells to self-destruct. Low doses of one anti-cancer drug currently in development, called Gamitrinib, sensitize tumor cells to a second drug, called TRAIL, also currently in clinical development as part of an anticancer regimen.

20 Apr 2011

New approach links cancer cell metabolism with poor clinical outcome

Identifying gene mutations in cancer patients to predict clinical outcome has been the cornerstone of cancer research for nearly three decades, but now researchers at the Kimmel Cancer Center at Jefferson have invented a new approach that instead links cancer cell metabolism with poor clinical outcome. This approach can now be applied to virtually any type of human cancer cell.

15 Apr 2011

Experimental Biology 2011 to be held April 9-13 in Washington, D.C.

The meeting Experimental Biology 2011 (EB 2011) begins April 9 and runs through April 13 at the Walter E. Washington Convention Center in Washington, D.C.

8 Apr 2011

Experts to discuss about links between metabolic function and disease at EB2011

Metabolism encompasses the biochemical reactions that sustain life and is usually thought of as two complementary systems: one that breaks down nutrients to generate energy and another that harnesses this energy to produce the building blocks cells need to thrive.

8 Apr 2011

Synta presents ganetespib and elesclomol study data in cancer at AACR meeting

Synta Pharmaceuticals Corp. today presented five posters at the American Association for Cancer Research 102nd Annual Meeting. Three posters reported results from studies of ganetespib, and two posters reported results from studies of elesclomol, a small-molecule mitochondria metabolism inhibitor.

5 Apr 2011

Stealth announces Bendavia Phase I clinical study results against ischemia reperfusion injury

Stealth Peptides Inc., a privately held biopharmaceutical company developing innovative therapies, announced today the results of a healthy volunteers Phase I clinical study of Bendavia™, a novel compound that targets the mitochondrion to treat ischemia reperfusion injury.

4 Apr 2011

Mitochondrial defect inherited from mother is linked to high blood pressure in one Chinese family

A specific genetic defect in one Chinese family shows that high blood pressure was inherited from the female parent, researchers report in Circulation Research: Journal of the American Heart Association.

1 Apr 2011

Researchers find patients with Alzheimer's have lower glucose utilization in brain

Researchers at Mount Sinai School of Medicine have found that patients with Alzheimer's disease have lower glucose utilization in the brain than those with normal cognitive function, and that those decreased levels may be detectable approximately 20 years prior to the first symptoms of Alzheimer's disease.

29 Mar 2011

New discovery may improve cochlear implants for deafness

University of Utah scientists used invisible infrared light to make rat heart cells contract and toadfish inner-ear cells send signals to the brain.

28 Mar 2011

Researchers identify new mechanism underlying MS

Multiple sclerosis is a disabling autoimmune disease in which nerve fibers are attacked by the patient's own immune system. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a new mechanism that contributes to nerve fiber damage - and shown that this damage can be reversed.

28 Mar 2011

Elevations in 5 amino acids may signal future disease risk

Measuring the levels of small molecules in the blood may be able to identify individuals at elevated risk of developing type 2 diabetes as much as a decade before symptoms of the disorder appear.

21 Mar 2011

Non-laser light treatments may help treat common skin conditions

While dermatologists have used lasers successfully for years to treat common skin conditions such as acne, rosacea and aging skin, it now appears that even non-laser lights may provide some of the same benefits.

16 Mar 2011

Malaria drug shrinks, slows resistant pancreatic tumors

Dana-Farber Cancer Institute scientists report they have shrunk or slowed the growth of notoriously resistant pancreatic tumors in mice, using a drug routinely prescribed for malaria and rheumatoid arthritis.

16 Mar 2011

Study identifies potential therapeutic target for neurodegenerative disorders

Cell biologists pondering the death of neurons - brain cells - said today that by eliminating one ingredient from the cellular machinery, they prolonged the life of neurons stressed by a pesticide chemical. The finding identifies a potential therapeutic target to slow changes that lead to neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.

14 Mar 2011