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Experts analyze data that can guide antidepressant discontinuation

There has been a lot of attention to problems patients face in discontinuing antidepressant drugs. However, there appear to be few indications, particularly in guidelines and reviews.

13 Dec 2018

New substance could improve efficacy of established breast cancer treatments

Physicians from Karl Landsteiner University of Health Sciences in Krems (Austria) demonstrate potential for clinical application, collaborating with research groups from Germany, the USA, and China.

13 Dec 2018

Baculovirus virion completely eliminates liver-stage parasites in mouse model

Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasites, which can lay dormant for months or years as in the case of Plasmodium vivax. Researchers from Kanazawa University have successfully demonstrated that administration of a baculovirus virion completely eliminates liver-stage parasites in a mouse model via BV-induced fast-acting innate immunity.

13 Dec 2018

Novel way to efficiently deliver anti-parasitic medicines

Scientists have developed a new way to deliver anti-parasitic medicines more efficiently.

12 Dec 2018

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Researchers from the Virginia Tech School of Neuroscience are teaming with the University of California San Diego and the U.S. National Institutes of Health to develop a drug -- now in its earliest stages -- that can treat certain types of chronic pain without the addictive consequences of opioids.

12 Dec 2018

Genetics study offers hope for new acne treatment

A discovery by researchers from the School of Basic & Medical Biosciences and NIHR Guy's and St Thomas' Biomedical Research Centre could lead to new treatments for severe acne. Scientists found 15 genome regions linked to developing the condition.

12 Dec 2018

New method helps better understand pathological development of ALS

The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose contact with the muscles as their axons atrophy.

12 Dec 2018

Insights into magnetotactic bacteria could guide development of biological nanorobots

Magnetotactic bacteria are a unique aquatic species which use magnetic nanoparticles as an internal compass to navigate

12 Dec 2018

New collaborative partnership in quest of novel antibiotics

The Global Antibiotic Research and Development Partnership, Eisai Co., Ltd. and Takeda Pharmaceutical Company Limited have signed an agreement for GARDP to access and screen components of Eisai and Takeda's chemical libraries.

12 Dec 2018

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

According to some estimates, up to one in three people around the world may experience severe anxiety in their lifetime.

12 Dec 2018

Study highlights factors that can reduce food cravings

Food craving, the intense desire to eat certain foods, can sabotage efforts to maintain healthy eating habits and body weight, no matter the time of year.

12 Dec 2018

Findings may open up new ways to treat dwarfism and other ER-stress-related conditions

Pseudoachondroplasia (PSACH) is a severe inherited dwarfing condition characterized by disproportionate short stature, joint laxity, pain, and early onset osteoarthritis.

12 Dec 2018

FDA issues warning letter to Zhejiang Huahai Pharmaceutical involved in valsartan recall

The U.S. Food and Drug Administration today released a warning letter issued to Zhejiang Huahai Pharmaceutical Co. Ltd. (ZHP), in Linhai, Taizhou Zhejiang China, the manufacturer of the active pharmaceutical ingredient (API) found in valsartan that is the subject of an ongoing FDA investigation into probable cancer-causing impurities in certain commonly prescribed heart medicines.

12 Dec 2018

NIH offers support for HIV care and prevention research in the southern United States

The National Institute of Allergy and Infectious Diseases will fund a series of collaborations with medical research institutions in the southern United States to test new ways of implementing HIV treatment and prevention tools in counties with some of the highest rates of new HIV cases nationwide.

12 Dec 2018

Disrupted biological clock can contribute to onset of diseases, USC study shows

USC scientists report that a novel time-keeping mechanism within liver cells that helps sustain key organ tasks can contribute to diseases when its natural rhythm is disrupted.

11 Dec 2018

Innovative care model for children with ASD reduces use of behavioral drugs in ED

An innovative care model developed by Nemours Children's Hospital for children with autism spectrum disorders in the emergency department reduces the use of medication administered to kids who are prone to stress and sensory overload in this care setting.

11 Dec 2018

Gut bacteria may modify effectiveness of anti-diabetes drugs

Why do orally-administered drugs for diabetes work for some people but not others? According to researchers at Wake Forest School of Medicine, bacteria that make up the gut microbiome may be the culprit.

11 Dec 2018

Drug repositioning strategy identifies potential new treatments for epilepsy

Drug repositioning-- taking known drugs and identifying new applications for them--is an attractive concept for speeding up the process of bringing drugs to human testing for unmet medical needs.

11 Dec 2018

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

11 Dec 2018

ESMO Immuno-Oncology Congress showcases novel technologies set to benefit many cancer patients

Innovation in immuno-oncology is exploding and new technologies that are set to benefit many patients with cancer are being showcased in the highly diverse array of topics to be discussed at the ESMO Immuno-Oncology Congress, to be held 13-16 December in Geneva, Switzerland.

11 Dec 2018

Drugs News and Research

Experts analyze data that can guide antidepressant discontinuation

New substance could improve efficacy of established breast cancer treatments

Baculovirus virion completely eliminates liver-stage parasites in mouse model

Novel way to efficiently deliver anti-parasitic medicines

Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain

Genetics study offers hope for new acne treatment

New method helps better understand pathological development of ALS

Insights into magnetotactic bacteria could guide development of biological nanorobots

New collaborative partnership in quest of novel antibiotics

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

Study highlights factors that can reduce food cravings

Findings may open up new ways to treat dwarfism and other ER-stress-related conditions

FDA issues warning letter to Zhejiang Huahai Pharmaceutical involved in valsartan recall

NIH offers support for HIV care and prevention research in the southern United States

Disrupted biological clock can contribute to onset of diseases, USC study shows

Innovative care model for children with ASD reduces use of behavioral drugs in ED

Gut bacteria may modify effectiveness of anti-diabetes drugs

Drug repositioning strategy identifies potential new treatments for epilepsy

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

ESMO Immuno-Oncology Congress showcases novel technologies set to benefit many cancer patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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