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Breakthrough technology identifies proteins' nearest neighbors on cell surfaces

When corporate partners in the Princeton Catalysis Initiative sat down two years ago with David MacMillan, they presented him with a biological challenge at the heart of potential cancer medicines and other therapeutics: which proteins on a cell's surface touch each other?

5 Mar 2020

New sepsis intervention enhances the body's bacteria-capturing neutrophil extracellular traps

Researchers at Children's Hospital of Philadelphia have developed a novel treatment for sepsis - one of the leading causes of hospital death - that enhances the body's bacteria-capturing neutrophil extracellular traps so that they more effectively capture infectious bacteria, resist degradation, and improve sepsis outcomes and survival.

5 Mar 2020

Research shows how Chlamydia pathogen invades human cells

Together with scientists from Paris and Munich, a team of researchers working under Prof. Dr. Johannes Hegemann and Dr. Katja Moelleken has published these findings in the journal Proceedings of the National Academy of Sciences of the United States of America.

5 Mar 2020

Coronavirus is mutating with a second strain identified by scientists

The coronavirus is mutating as scientists identified a second strain, which is more aggressive and contagious.

5 Mar 2020

X-ray free electron laser helps probe deeper into deadly pathogen

Tularemia is a rare but often lethal disease. It is caused by one of the most aggressive pathogens on earth, the bacterium Francisella tularensis.

5 Mar 2020

Researchers identify a gut microbe generated byproduct linked to cardiovascular disease

Cleveland Clinic researchers have identified a gut microbe generated byproduct - phenylacetylglutamine - that is linked to development of cardiovascular disease, including heart attack, stroke and death.

5 Mar 2020

Children with a rare food allergy have higher chance of being diagnosed with other allergies

Researchers at Children's Hospital of Philadelphia have found that children with a rare food allergy known as food protein-induced enterocolitis syndrome, or FPIES, have a significantly higher chance of being diagnosed with other allergic conditions, including eczema, traditional food allergy and asthma.

5 Mar 2020

Social isolation could be linked to increased inflammation in the body

Social isolation could be associated with increased inflammation in the body new research from the University of Surrey and Brunel University London has found.

5 Mar 2020

Researchers uncover novel neurotransmitter system in the brain

Neurotransmitters are chemicals that transmit signals between neurons or from neurons to other cells. They interact with specific receptors found in the brain of humans and animals, controlling a variety of biological processes, e.g. fear, anger, pleasure, memory, energy, appetite and sleep.

5 Mar 2020

Curcumin can be delivered effectively into cells via tiny nanoparticles

For years, curry lovers have sworn by the anti-inflammatory properties of turmeric, but its active compound, curcumin, has long frustrated scientists hoping to validate these claims with clinical studies.

5 Mar 2020

Norwegian national center receives NOK 22.5 million for the fight against Alzheimer's disease

The Foundation Stiftelsen Kristian Gerhard Jebsen has donated NOK 22.5 million to a Norwegian national center for the fight against Alzheimer's disease. The grant was made public on 26 February.

5 Mar 2020

Eating an egg a day is OK

A new study and meta-analysis released by the Harvard T. H. Chan of Public Health shows that it is safe to eat up to 1 egg a day without worrying about whether it is harming the health of the heart and blood vessels. The study was published online on March 4, 2020, in the journal BMJ.

4 Mar 2020

Nearly $4 million to fund drug discovery research for Alzheimer's, other dementia

The Alzheimer's Association and the Rainwater Charitable Foundation have joined forces again to fund drug discovery research towards finding therapies for Alzheimer's disease, frontotemporal degeneration, and other tauopathies.

4 Mar 2020

Biomaterials could soon create tissue like blood vessel structures

A group of researchers led by Professor Alvaro Mata from the University of Nottingham, along with others from Queen Mary University London, has successfully created a biomaterial that could be used for the creation of tissues that could form blood vessels. The study titled, “Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices,” was published in the latest issue of the journal Nature Communications.

4 Mar 2020

How do cells protect themselves from viruses?

Amid the coronavirus outbreak that is wreaking havoc across the globe, it is essential to know how the cells of the body evade infection from viruses. A team of scientists has explained the mechanism that takes place in case a virus penetrates the body.

4 Mar 2020

Yale discovery has implications for treatment of diabetes and non-alcoholic fatty liver disease

Many health problems in the developed world stem from the disruption of a delicate metabolic balance between glucose production and energy utilization in the liver.

4 Mar 2020

New repair mechanism for alcohol-induced DNA damage discovered

Researchers of the Hubrecht Institute in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol.

4 Mar 2020