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Lack or loss of SIRT3 protein induces proliferation of breast cancer cells

Research published in the Cancer Cell journal in March was a significant step in knowing the causes of cancer better, especially breast cancer, revealing that the lack or loss of a protein in the cells known as SIRT3, induces the proliferation of this disease and thereby, this protein can be an may be a therapeutic target in the development of effective therapies for cancer. The research was led by Dra. Marcia Haigis of the Harvard Medical School, with the participation of Dr. Arkaitz Carracedo, from the Proteomics Laboratory at CIC bioGUNE.

6 Apr 2011

UT Southwestern gynecologist receives Burroughs Wellcome Fund for premature birth study

A UT Southwestern Medical Center gynecologist is one of five researchers nationwide selected to receive a $600,000 Burroughs Wellcome Fund grant to investigate the biological mechanisms and causes of premature birth.

6 Apr 2011

Adipocytes associated with breast cancer could amplify 'aggressive' effect of tumors in obese patients

Apart from its direct effect on health (such as cardiovascular diseases and diabetes), obesity is increasingly suspected of playing a role in the prognosis of breast cancer and, in particular, its propensity to spread. However, no direct cause and effect relationship had been demonstrated until now. This breakthrough has finally been made through the collaborative work of two teams of researchers from Inserm, CNRS and the Université Paul Sabatier.

6 Apr 2011

Teenagers with scoliosis can benefit from new generation spine implants

Teenagers who undergo spine fusion for scoliosis using the newest surgical techniques can expect to be doing well 10 years after surgery, according to a Hospital for Special Surgery study published online ahead of print in the TK issue of the journal Spine.

6 Apr 2011

Two reports show drastic increase in opioid prescriptions in America

Two reports by addiction researchers at the University of Pennsylvania School of Medicine and the National Institute on Drug Abuse show a drastic shift in prescribing patterns impacting the magnitude of opioid substance abuse in America.

6 Apr 2011

Editorial cautions against estrogen-only hormone therapy after hysterectomy

An editorial in the April 6 issue of the Journal of the American Medical Association cautions against estrogen-only hormone therapy in women who have had a hysterectomy because of longstanding evidence that it raises the risk of breast cancer.

6 Apr 2011

Scientists uncover SREBP-2 role in autophagy and cholesterol generation

Not all cholesterol is bad. Every cell requires it for growth - they either have to get cholesterol somewhere or they die. In a new study published April 6 in the journal Cell Metabolism, researchers from Sanford-Burnham Medical Research Institute and their collaborators found that a protein sensor known to balance cholesterol sources can also access a previously underappreciated cellular fat storage depot.

6 Apr 2011

Ryan budget plan would reshape Medicare, Medicaid

The blueprint advanced by House Budget Committee Chairman Paul Ryan, R-Wis., would attempt to rein in the long-term costs of Medicare and Medicaid while squeezing $6.2 trillion dollars from the nation's deficit over the next 10 years. The plan, which will be released today, comes as congressional leaders continue to face an impasse on short-term budget negotiations to avert a government shutdown.

6 Apr 2011

Treating obstructive sleep apnea in stroke patients improves recovery from stroke

A new study shows that patients in stroke rehabilitation treated for their co-existing obstructive sleep apnea (OSA) recovered better from stroke than those whose OSA was not treated.

6 Apr 2011

Viewpoints: Ryan on his budget plan; Maryland, Wash. state making tough budget choices

The open-ended, blank-check nature of the Medicare subsidy threatens the solvency of this critical program and creates inexcusable levels of waste. This budget takes action where others have ducked. But because government should not force people to reorganize their lives, its reforms will not affect those in or near retirement in any way.

6 Apr 2011

More than 900 young Britons diagnosed with the deadliest form of skin cancer each year

Each day more than two people under 35 in Britain are diagnosed with malignant melanoma - the deadliest form of skin cancer - according to new figures from Cancer Research UK.

6 Apr 2011

Caliper's CDAS unit enters cancer research collaboration with Denver-based CHI

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life-sciences research, today announced that its Caliper Discovery Alliances and Services unit has formed a research collaboration with Denver-based Catholic Health Initiatives, one of the nation's largest health systems.

6 Apr 2011

Sleep apnea people may face risk of suffering ischemic stroke

According to research presented at the School of Medicine and the University of Navarra Hospital by Dr. Roberto Muñoz, a physician of the Neurology Service of the Hospital Complex of Navarra, those persons with serious cases of sleep apnea have more than twice the possibility of suffering an ischemic stroke. Specifically, 2.5 times more.

6 Apr 2011

Meditation for pain succeeds: Study

According to a new study meditation may help in reducing pain. For the study researchers mildly burned 15 men and women in a lab on two separate occasions, before and after the volunteers attended four 20-minute meditation training sessions over the course of four days. During the second round, when the participants were instructed to meditate, they rated the exact same pain stimulus - a 120-degree heat on their calves - as being 57 percent less unpleasant and 40 percent less intense, on average.

5 Apr 2011

Estrogen only hormone replacement not so risky after 50’s: Study

According to a new study hormone therapy may not be as risky for elder women as earlier thought. This comes from the Women's Health Initiative, a federally funded trial that tracked thousands of women taking hormones or placebo pills for years. The WHI looked at women who have had hysterectomies or have had their uterus removed and thus can take estrogen unaccompanied by another hormone, progestin. It found that a heightened risk of stroke from taking estrogen faded with time, while a reduced risk of breast cancer held steady.

5 Apr 2011

OSU chemist developing solution to nerve agent exposure

Scientists are working to develop a new drug that will regenerate a critical enzyme in the human body that “ages” after a person is exposed to deadly chemical warfare agents.

5 Apr 2011

How materialistic advertising messages negatively shape the female body image

Psychological research has consistently shown that women feel unhappy with their body after looking at images of thin, idealized models, which are typically represented in the media. However, today's consumer culture and media promote not only the ideal of perfect beauty, but also that of the material affluent lifestyle, both of which are commonly depicted together, and highlight the benefits of beauty and of owning material goods to one's personal success and fame.

5 Apr 2011

Zebrafish research suggests new drug targets and markers to help treat melanoma

Thanks to the zebrafish, there is new hope for people with melanoma, an aggressive skin cancer that is responsible for approximately 8,700 deaths each year in the United States.

5 Apr 2011

ARIAD's ponatinib potently inhibits all four FGFRs abnormally expressed in multiple cancers

ARIAD Pharmaceuticals, Inc. today announced results of preclinical studies on ponatinib, its investigational pan-BCR-ABL inhibitor, showing potent inhibition of all four members of the fibroblast growth factor receptor (FGFR) family of tyrosine kinases that are abnormally expressed in multiple cancers. ARIAD scientists are presenting the data this morning at the American Association for Cancer Research (AACR) Annual Meeting in Orlando, Florida.

5 Apr 2011

CAPP introduces new initiative on accountable care for public

The Council of Accountable Physician Practices, an affiliate of the American Medical Group Association, today announced a new initiative to provide the public, media, and policymakers with resources and information about the value of care coordination and accountable care to national health care reform.

5 Apr 2011