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New class of chemically produced antimicrobial agents could become future infection treatment alternative

The World Health Organization (WHO) has named antimicrobial resistance one of the most important threats to human health. We therefore need to find new compounds that can be used as future alternatives to conventional antibiotics.

20 Jul 2012

Mother's exposure to air pollution increases risk of obesity and insulin resistance in offspring

Pregnant mice exposed to high levels of air pollution gave birth to offspring with a significantly higher rate of obesity and insulin resistance in adulthood than those that were not exposed to air pollution. This effect seemed especially prevalent in male mice, which were heavier regardless of diet. These findings, published online in the FASEB Journal, suggests a link between diesel exhaust exposure in utero and bulging waistlines in adulthood.

20 Jul 2012

Sanquin, Baxter enter manufacturing services agreement for plasma therapies

Baxter International Inc. today announced that it has entered into a manufacturing services agreement with Stichting Sanquin Bloedvoorziening (Sanquin Blood Supply Foundation) in the Netherlands that will provide Baxter up to 1.6 million liters of incremental plasma fractionation capacity annually to support global growth of plasma-derived treatments.

From Baxter International Inc. 20 Jul 2012

Natural compound can virtually eradicate HIV in infected culture cells

A new study by scientists on the Florida campus of The Scripps Research Institute shows, in cell culture, a natural compound can virtually eliminate human immunodeficiency virus (HIV) in infected cells. The compound defines a novel class of HIV anti-viral drugs endowed with the capacity to repress viral replication in acutely and chronically infected cells.

20 Jul 2012

Keystone Symposia on Molecular and Cellular Biology receives Gates Foundation grant

Keystone Symposia on Molecular and Cellular Biology is pleased to announce that it has received a fourth grant from the Bill & Melinda Gates Foundation to promote discoveries that will solve urgent global health problems via support of infectious disease conferences in the "Keystone Symposia Global Health Series."

20 Jul 2012

Scientists develop simple assay to diagnose 'superparasites'

Belgian scientists of the Institute of Tropical Medicine (ITM) in Antwerp, Belgium made a breakthrough in bridging high tech molecular biology research on microbial pathogens and the needs of the poorest of the poor. After sequencing the complete genome of Leishmania donovani (a parasite causing one of the most important tropical diseases after malaria) in hundreds of clinical isolates, they identified a series of mutations specific of 'superparasites' and developed a simple assay that should allow tracking them anywhere.

20 Jul 2012

Short-term infection with intestinal worms may provide long-term protection against TID

Short-term infection with intestinal worms may provide long-term protection against type I diabetes (TID), suggests a study conducted by William Gause, PhD, and colleagues at the University of Medicine and Dentistry of New Jersey-New Jersey Medical School.

20 Jul 2012

Studies report on therapeutic efficacy of stem cell transplantation in animal models of ALS, SCI

Two studies published in a recent issue of Cell Medicine report on the therapeutic efficacy of stem cell transplantation in animal models of amyotrophic lateral sclerosis (ALS) and spinal cord injury (SCI).

20 Jul 2012

BioDiem signs agreement with RMIT to create new non-influenza vaccines

Australian infectious disease therapy and vaccine development company BioDiem Ltd (ASX: BDM) today announced that BioDiem has signed an agreement with The Royal Melbourne Institute of Technology (RMIT) regarding a research program that will investigate the use of BioDiem’s live attenuated influenza virus (LAIV) to create new non-influenza vaccines. Developing the potential of the LAIV technology for new indications is an important part of BioDiem’s strategy, and this research is part of the work towards that goal.

19 Jul 2012

Primcogent Solutions introduces low level laser therapy for onychomycosis

Primcogent Solutions - supplier of the revolutionary ZERONA non-invasive body contouring technology in North America and Western Europe - has announced the launch of Lunula Laser, a clinically proven, low level laser therapy for onychomycosis, for distribution exclusively in Europe.

19 Jul 2012

Researchers discover potential drug targets that might reduce ventilator-induced lung inflammation

When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can lead to excessive inflammation, new research suggests.

19 Jul 2012

UNMC's ART injectables can successfully treat HIV infection

This has been a good week for breakthroughs in HIV/AIDS. Earlier this week, the Food and Drug Administration approved a daily pill, Truvada, which reduces the risk of HIV infection. Today, a University of Nebraska Medical Center research team's progress toward developing weekly or twice-monthly injectable antiretroviral therapy (ART) nanomedicines for patients with human immunodeficiency virus (HIV) infection will be highlighted as the cover story in the Journal of Infectious Diseases.

19 Jul 2012

Duke-led consortium to focus on inducing neutralizing antibodies for HIV-1 prevention

Two Los Alamos National Laboratory scientists are among the team recently funded to explore ways to create the precise immune factors needed for effective vaccines against HIV.

19 Jul 2012

Egg allergies in children can be treated with oral immunotherapy

Giving children with egg allergies increasingly higher doses of the very food they are allergic to can eliminate or ease reactions in most of them, according to results from a federally funded study conducted at Johns Hopkins Children's Center and four other U.S. institutions.

19 Jul 2012

Study gauges depression among spouses of severe-sepsis survivors

Severe sepsis, a body's dangerous defensive response against an infection, not only diminishes the quality of life for patients - it puts their spouses at a greater risk of depression, a joint University of Michigan Health System and University of Washington School of Medicine study shows.

19 Jul 2012

Inhibiting STAT3 might unleash an effective anti-lymphoma immune response

Researchers at Moffitt Cancer Center and colleagues have demonstrated that the inhibition of signal transducer and activator of transcription 3 (STAT3) in mouse models of mantle cell lymphoma (MCL), an aggressive and incurable subtype of B-cell non-Hodgkin lymphoma that becomes resistant to treatment, can harness the immune system to eradicate residual malignant cells responsible for disease relapse.

19 Jul 2012

Abscisic acid has anti-inflammatory effects in the lungs and gut

Building on previous work with the botanical abscisic acida, researchers in the Nutritional Immunology and Molecular Medicine Laboratory (NIMML) have discovered that abscisic acid has anti-inflammatory effects in the lungs as well as in the gut.

19 Jul 2012

Researchers uncover mechanism by which aging may weaken immune response

Researchers at Albert Einstein College of Medicine of Yeshiva University have uncovered one of the mechanisms by which aging may compromise the ability of the immune system to fight infections and respond to vaccines.

18 Jul 2012

Kawasaki Disease may increase risk of atherosclerosis in children

Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults.

18 Jul 2012

Combination of Dox with MCP shows promise against prostate cancer

Doxorubicin (Dox) is an effective anti-cancer drug, but it's also a very toxic one, causing severe heart and immune damage. The doses needed to impact tumors are not well tolerated by patients, however, researchers may have found an answer through combination therapy.

18 Jul 2012

Immune System News and Research

New class of chemically produced antimicrobial agents could become future infection treatment alternative

Mother's exposure to air pollution increases risk of obesity and insulin resistance in offspring

Sanquin, Baxter enter manufacturing services agreement for plasma therapies

Natural compound can virtually eradicate HIV in infected culture cells

Keystone Symposia on Molecular and Cellular Biology receives Gates Foundation grant

Scientists develop simple assay to diagnose 'superparasites'

Short-term infection with intestinal worms may provide long-term protection against TID

Studies report on therapeutic efficacy of stem cell transplantation in animal models of ALS, SCI

BioDiem signs agreement with RMIT to create new non-influenza vaccines

Primcogent Solutions introduces low level laser therapy for onychomycosis

Researchers discover potential drug targets that might reduce ventilator-induced lung inflammation

UNMC's ART injectables can successfully treat HIV infection

Duke-led consortium to focus on inducing neutralizing antibodies for HIV-1 prevention

Egg allergies in children can be treated with oral immunotherapy

Study gauges depression among spouses of severe-sepsis survivors

Inhibiting STAT3 might unleash an effective anti-lymphoma immune response

Abscisic acid has anti-inflammatory effects in the lungs and gut

Researchers uncover mechanism by which aging may weaken immune response

Kawasaki Disease may increase risk of atherosclerosis in children

Combination of Dox with MCP shows promise against prostate cancer

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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