Medicine News and Research

RSS

Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery – until possibly now.

17 Mar 2023

Severe COVID-19 increases the risk of developing heart disease later in life

Patients who have been hospitalized with severe COVID-19 have permanent changes in their cholesterol 3 months after recovery, according to a study from the University of Oslo. This increases their risk of developing heart disease later in life.

17 Mar 2023

Novel therapeutic eradicates gastric cancer in treated mice

A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.

17 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

17 Mar 2023

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Tyrosine kinase inhibitors are a type of targeted cancer medicine that can attack specific types of cancer cells and prevent them from multiplying.

17 Mar 2023

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans.

17 Mar 2023

Stanford researchers study causes of and treatments for long COVID

Time heals many wounds. But not all of them.

17 Mar 2023

Computational analysis of large genetic datasets reveals rare disease etiologies

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

17 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Detecting tissue-resident memory T cells in solid tumors

In this interview, NewsMedical talks with Cerba Research about in situ multiplex analysis of regulatory and effector T cells in tumors.

16 Mar 2023

How to assess clinical response in multiple myeloma

In this interview, Cerba Research explains how its teams were able to assess clinical response in multiple myeloma (MM) patients that were receiving monoclonal antibodies treatment,

From Cerba Research 16 Mar 2023

Creating more effective and safe treatments for COVID-19

When approaching a task, members of a team need to work in synergy. Nothing can be accomplished if you're pulling in different directions.

16 Mar 2023

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

Researchers documented the various polymeric materials that can be used to synthesize micelles, which can then be used for targeted cancer therapy by tailoring the micelles to respond to stimuli.

16 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Since the development of functional magnetic resonance imaging in the 1990s, the reliance on neuroimaging has skyrocketed as researchers investigate how fMRI data from the brain at rest, and anatomical brain structure itself, can be used to predict individual traits, such as depression, cognitive decline, and brain disorders.

16 Mar 2023

Global maternal Strep B immunization program may save millions of dollars in healthcare costs

A global maternal immunization program for group B Streptococcus - Strep B - would save millions of dollars in healthcare costs by reducing death and disability, a team led by researchers from the London School of Hygiene & Tropical Medicine has found.

16 Mar 2023

Medicine News and Research

Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

Severe COVID-19 increases the risk of developing heart disease later in life

Novel therapeutic eradicates gastric cancer in treated mice

Scientists develop a marker for therapy response in acute myeloid leukemia

Designer DNA drug could be used to delay paralysis in ALS

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Stanford researchers study causes of and treatments for long COVID

Computational analysis of large genetic datasets reveals rare disease etiologies

Loss of a beta cell subset might contribute to type 2 diabetes

Study implicates gut microbiome and immune response in hospital-acquired infections

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Detecting tissue-resident memory T cells in solid tumors

How to assess clinical response in multiple myeloma

Creating more effective and safe treatments for COVID-19

Stimulus-sensitive polymeric micelles show promise for future targeted drug delivery and chemotherapy

Scientists develop genetically defined mouse models for multiple myeloma subtypes

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Global maternal Strep B immunization program may save millions of dollars in healthcare costs

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News