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New alliance for discovery of WNT pathway inhibitors to be used in cancer therapy

Cancer Research Technology (CRT), Merck Serono, a division of Merck KGaA, Darmstadt, Germany, Cancer Research UK, Cardiff University and The Institute of Cancer Research (ICR) are set to begin a major new research collaboration for the first time. This will provide substantial investment in research on the WNT signalling pathway in the hope of finding new drug targets.

15 Jul 2009

Cost of road deaths in Australia's underestimated

New research re-evaluating the cost of a human lives lost in car accidents should make proposed improvements to Australia's roads more worthwhile, says a leading University of Sydney transport expert.

15 Jul 2009

Surprising new insights into the repair strategies of DNA

A microscopic single-celled organism, adapted to survive in some of the harshest environments on earth, could help scientists gain a better understanding of how cancer cells behave.

15 Jul 2009

New drug blocks common cancer pathway

Scientists have developed a new drug which can reduce the growth of tumours in mice by up to 98 per cent, according to a study published in Molecular Cancer Therapeutics ** this week.

15 Jul 2009

eHealth record system a step closer

The introduction of a national eHealth record systems appears to be progressing with delegates at the Australian Health Ministers' Conference agreeing to establishing a secure national system.

15 Jul 2009

Novartis to partner with OneWorld Health to develop diarrhea drug

"Swiss drug company Novartis AG and the Institute for OneWorld Health, a nonprofit group, will announce this week a partnership to discover drugs for a type of diarrhea that kills about 1.6 million children each year in the developing world," the Wall Street Journal reports.

15 Jul 2009

WHO recommends vaccine makers move forward in mass production of H1N1 vaccine

"Saying the new H1N1 [swine flu] virus is 'unstoppable', the WHO gave drug makers a full go-ahead to manufacture vaccines against the pandemic influenza strain on Monday and said healthcare workers should be the first to get one," Reuters reports (Fox, 7/14).

15 Jul 2009

Skin cancer researchers throw new light on tumour growth

Three researchers from the Dermatology Research Foundation at the University of Sydney have identified a compound produced by certain fatal skin cancer tumours, providing new hope for developing treatments.

14 Jul 2009

Why oral contraceptives fail for obese women

Researchers have identified a potential biological mechanism that could explain why oral contraceptives may be less effective at preventing pregnancy in obese women, as some epidemiological studies have indicated.

14 Jul 2009

Study finds survival rates from GIST improving among African-Americans

New research published in the July issue of the Journal of the American College of Surgeons reveals that African Americans with gastrointestinal stromal tumors (GIST), a rare cancer that begins in the wall of the gastrointestinal tract, now have survival rates equivalent to those of Caucasians. Prior to 2000, African Americans were more likely to develop GIST and less likely to undergo surgical treatment for this type of cancer.

14 Jul 2009

Special pathway makes bacteria vulnerable - new target for tailored antibiotics

More and more strains of bacteria are developing resistance to previously life-saving antibiotics. Researchers at TUM, the Technische Universitaet Muenchen, have shed light on a metabolic step that appears in many aggressive microorganisms -- such as tuberculosis and malaria pathogens -- and that may provide a promising target for a new class of antibiotics. The researchers present their results in the chemistry journal Angewandte Chemie.

14 Jul 2009

Childhood cancer risk rises with mother's age

Research from the Masonic Cancer Center, University of Minnesota indicates that a baby born to an older mother may have a slightly increased risk for many of the cancers that occur during childhood.

14 Jul 2009

Developing countries can successfully combat HIV/AIDS epidemic with generics

Brazil's nearly two-decade effort to treat people living with HIV and AIDS shows that developing countries can successfully combat the epidemic. Inexpensive generic medicines are a large part of the solution, say researchers from Brown University and the Harvard School of Public Health.

14 Jul 2009

Brain imaging (MRI/PET) bring us closer to earlier detection of Alzheimer's

Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.

14 Jul 2009

IQ explains some of the difference in heart disease between people of high and low socio-economic status

A unique study looking at the difference in cardiovascular disease (heart disease and stroke) and life expectancy between people of high and low socio-economic status has found that a person's IQ may have a role to play.

14 Jul 2009

Hospital workers smoking – only the most addicted flout the rules

A survey of staff at Addenbrooke's hospital has shown that those who break the smoke-free policy are generally more addicted than those who respect it. Researchers writing in the open access journal BMC Public Health also investigated staff's attitude to the smoke-free policy and found that smokers were less likely to believe that the policy would protect people from second hand smoke.

14 Jul 2009

Researchers try to predict who is going to develop Alzheimer's in the future

A new Mayo Clinic study found that the clinical criteria for mild cognitive impairment is better at predicting who will develop Alzheimer's disease than a single memory test. This is one more piece of information to aid in the identification and early treatment of individuals most likely to develop Alzheimer's disease.

14 Jul 2009

Discovery of brain-protecting protein

Johns Hopkins researchers have discovered a novel protein that can protect brain cells by interrupting a naturally occurring "stress cascade" resulting in cell death.

14 Jul 2009

Researchers design textile load limiter for child seat belt systems

The team of researchers from the Applus+ Chair has designed a load limiter that reduces the pressure on the chest area by absorbing part of the energy produced in a frontal impact. The system reduces the speed at which the child is thrown forward and back into the seat, a movement that leads to serious injury in many accidents.

14 Jul 2009

Moderate alcohol intake reduces the risk of dementia in seniors

A glass of wine here, a nightcap there - new research out of Wake Forest University School of Medicine suggests that moderate alcohol intake offers long-term cognitive protection and reduces the risk of dementia in older adults. The study is being presented at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD), in Vienna on July 13.

14 Jul 2009