G Protein News and Research

RSS

NIDDK awards $1.2 million grant to Bolder BioTechnology for long-acting EPO analog program

Bolder BioTechnology, Inc. announced today that it has been awarded a $1.2 million Phase II Small Business Innovation Research (SBIR) grant, entitled "Long-Acting EPO Analog for Treating Anemia Associated with Chronic Kidney Disease," from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of The National Institutes of Health (NIH). Receipt of the entire grant award is contingent upon the achievement of certain research milestones.

18 Sep 2009

Study reveals that low invadolysin could reduce fat storage in lipids

Researchers at the University of Edinburgh have found that the protein invadolysin, which is essential for healthy cell division, is present in lipid droplets - the parts of cells used to store fat.

18 Sep 2009

Researchers link plasticity related gene-1 to lipid phosphates

In mice that are missing a protein found only in the brain, neural signals "go crazy," leaving the animals with epileptic seizures from a young age, researchers have found. The report in the September 18th Cell, a Cell Press publication, details what it is that happens when the protein encoded by plasticity related gene-1 (PRG-1) gets lost, revealing an important fine-tuning mechanism for brain function.

18 Sep 2009

Research reveals binge drinking weakens the body's ability to fight off infection

As if a bad hangover wasn't enough of a deterrent, new research has shown how binge drinking weakens the body's ability to fight off infection for at least 24 hours afterwards. The study, published today in the open access journal BMC Immunology, focused on the effect of heavy drinking on toll-like receptor 4 (TLR4), a protein that has an important role in immune system activation.

17 Sep 2009

Research reveals that reactive oxygen inhibition can limit cancer cell invasion

Researchers at the Burnham Institute for Medical Research (Burnham) have discovered that reactive oxygen species, such as superoxide and hydrogen peroxide, play a key role in forming invadopodia, cellular protrusions implicated in cancer cell migration and tumor metastasis.

17 Sep 2009

Protein aggregation is linked to many conformational diseases

Researchers at the Department of Biochemistry and Molecular Biology of Universitat Autònoma de Barcelona (UAB) have revealed the process by which proteins with a tendency to cause conformational diseases such as amyotrophic lateral sclerosis, familial amyloidotic polyneuropathy, familial amyloidotic cardiomyopathy, etc. finally end up causing them.

17 Sep 2009

Study reveals that YAP can be used for the diagnosis of gastric carcinoma

A research team led by Professor Yan Xin, from The Fourth Laboratory of Cancer Institute in China measured the expression of YAP and survivin in normal gastric mucosa, precancerous lesions and gastric carcinoma using an immunohistochemical method to analyze the significance and correlations of the 2 factors with gastric carcinogenesis.

17 Sep 2009

Mayo Clinic Women's HealthSource discusses myths and facts about ovarian cancer

But not all the news about ovarian cancer is grim. Incidence is declining. Doctors are learning more about early symptoms and more effective treatments. The September issue of Mayo Clinic Women's HealthSource looks at myths and facts about ovarian cancer.

17 Sep 2009

Findings may lead to drugs that destroy TB in dormant stage of lifecycle

Attempts to eradicate tuberculosis (TB) are stymied by the fact that the disease-causing bacteria have a sophisticated mechanism for surviving dormant in infected cells. Now, a team of scientists led by researchers from Weill Cornell Medical College has identified compounds that inhibit that mechanism -- without damaging human cells.

17 Sep 2009

Nuveta closes Series A seed financing round for in vitro fertilization research

Nuveta, Inc., a privately held medical device company and global leader in basic in vitro fertilization (IVF) research, announced today that it has closed a Series A seed financing round, solely funded by Vivo Ventures.

17 Sep 2009

Link between a key molecular player and human chromosomal birth defects established

Using yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis, a cell biologist at The Florida State University found that when a key molecular player known as Pds5 goes missing, chromosomes fail to segregate and pair up properly, and birth defects such as Down syndrome can result.

17 Sep 2009

CDC awards manufacturing contract to Arrayit Corporation

Arrayit Corporation (OTCBB: ARYC), a proprietary life sciences technology leader, announces that on September 11th, 2009, on the eighth anniversary of the World Trade Center attacks, the company won a competitive bid from the Centers for Disease Control in Atlanta, Georgia to manufacture devices designed to combat global bioterrorism.

17 Sep 2009

Protein kinase Erk3 plays a critical role in intrauterine growth and lung maturation

Dr. Sylvain Meloche, Principal Investigator at the Institute for Research in Immunology and Cancer (IRIC) of the Universit- de Montr-al, and his colleagues have uncovered the critical role played by the protein kinase Erk3 in fetal growth potential and lung maturation.

17 Sep 2009

Cellzome's quantitative chemical proteomics platform described in a journal

Cellzome announces today, the publication entitled "Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling" is now available online in Nature.

17 Sep 2009

AAPS partners with PhRMA to present Current Trends in Stability workshop

The American Association of Pharmaceutical Scientists (AAPS) is a professional, scientific society of approximately 12,000 members employed in industry, academia, government and other research institutes worldwide.

17 Sep 2009

New research shows that physical and psychological factors affect food choices

New research suggests that there are important psychological factors to consider when making a food choice.

17 Sep 2009

Molecular link between intelligence and curiosity discovered

Scientists from the Samuel Lunenfeld Research Institute of Mount Sinai Hospital in Toronto have discovered a molecular link between intelligence and curiosity, which may lead to the development of drugs to improve learning.

17 Sep 2009

Researchers discover HIV Nef protein's role in cell mobility inhibition

In order to be able to ward off disease pathogens, immune cells must be mobile and be able to establish contact with each other. The working group around Professor Dr. Oliver Fackler in the Virology Department of the Hygiene Institute of the Heidelberg University Hospital has discovered a mechanism in an animal model revealing how HIV, the AIDS pathogen, cripples immune cells: Cell mobility is inhibited by the HIV Nef protein.

17 Sep 2009

New technique found that may prevent vision loss

Blocking a protein that battles infection may help thwart a common cause of vision loss in chronic diseases such as diabetes, Medical College of Georgia researchers say.

16 Sep 2009

Cryosurgery: Primary treatment option for prostate cancer

After years of innovation and intensive research, a team of Binghamton University (BU) researchers working with Cell Preservation Services, Inc., Owego, NY has broken extraordinary new ground in the recognition of cryosurgery as a primary treatment option for prostate cancer.

16 Sep 2009