Immune System News and Research

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Vitamin D levels of newborns appear to predict their risk of respiratory infections

The vitamin D levels of newborn babies appear to predict their risk of respiratory infections during infancy and the occurrence of wheezing during early childhood, but not the risk of developing asthma. Results of a study in the January 2011 issue of Pediatrics support the theory that widespread vitamin D deficiency contributes to risk of infections.

27 Dec 2010

Gold-coated liposomes could make chemotherapy more effective without harmful side effects

University of Arizona researchers may have found a way to deliver chemotherapeutic drugs to cancer tissues in controlled doses without harming healthy body cells.

24 Dec 2010

Good Clostridia prevents development of allergies and inflammatory bowel disease

Scientists at the University of Tokyo have discovered that specific gut-dwelling bacteria control key immune cells that combat allergies and autoimmune diseases. The paper describing these findings was published in today's issue of the journal Science, and technology originating from the work is being advanced by start-up Vedanta Biosciences.

24 Dec 2010

Immunization with VLP vaccine results in functional, protective immune responses against RSV

Novavax, and scientists at the University of Massachusetts Medical School, led by Dr. Trudy Morrison, published in the January 2011 issue of The Journal of Virology, a report indicating that a novel virus-like particle vaccine candidate against respiratory syncytial virus (RSV) protects mice from a live virus challenge.

23 Dec 2010

Researchers identify new regulator that play a critical role in B cell development

A team at the Institut de recherches cliniques de Montr-al led by Dr. Tarik M-r-y, President and Scientific Director of the institute and Director of the Hematopoiesis and Cancer research unit, will be publishing an important breakthrough in tomorrow's issue of Immunity, a scientific journal from the Cell Press group. The researchers identified a new regulator playing a critical role in the development B cells, which produce antibodies.

23 Dec 2010

Certain drugs may block tumor host interactions but do not destroy cancer cells

A class of drugs thought to kill cancer cells may in fact block "cross talk" between the cancer cell and normal immune cells, resulting in reduced cancer growth and spread-a discovery that could significantly alter the way cancer drugs are evaluated in the future.

23 Dec 2010

Combination of antigen and wax nanoparticles improves immunogenicity

Particle Sciences, a leading pharmaceutical CRO has formulated a series of wax nanoparticles that, when coupled with an antigen, enhanced its immunogenicity, increasing both systemic and the mucosal immune response.

23 Dec 2010

Researchers discover protein that suppresses melanoma progression

In a breakthrough that could lead to new treatments for patients with malignant melanoma, researchers from Mount Sinai School of Medicine have discovered that a particular protein suppresses the progression of melanoma through regulation of an oncogene, or gene responsible for cancer growth. The study is published in the December 23 issue of Nature.

23 Dec 2010

Time magazine declares NYSCF member as 2010 "Person who Matters" for innovative stem cell research

The New York Stem Cell Foundation extends congratulations to Derrick Rossi, PhD, a member of the inaugural class of NYSCF-Robertson Investigators, who was named one of Time Magazine's 2010 "People Who Mattered" in the December 27, 2010 Person of the Year Issue.

22 Dec 2010

Therapies to target self-renewing population of chemotherapy-resistant cells needed

Leukemia patients whose cancers express higher levels of genes associated with cancer stem cells have a significantly poorer prognosis than patients with lower levels of the genes, say researchers at the Stanford University School of Medicine. The finding is among the first to show that the cancer stem cell hypothesis - which posits that some cancers spring from and are replenished by a small, hardy population of self-renewing cells - can be used to predict outcomes in a large group of patients and one day to tailor treatments in the clinic.

22 Dec 2010

Gold nanoparticles show great potential for tumour targeted drug delivery

The World Gold Council (WGC) is delighted with the successful phase 1 clinical trial of a unique nanomedicine that uses nanoparticles of gold as the core of a delivery system for tumour targeted drug delivery.

22 Dec 2010

Altering balance among immune system cells could hold potential for T2D-associated inflammation treatment

Researchers from Boston University School of Medicine (BUSM) have demonstrated that certain T cells require input from monocytes in order to maintain their pro-inflammatory response in people with type 2 diabetes (T2D). The study also showed, for the first time, how a loss in homeostasis in this group of T cells most likely promotes chronic inflammation associated with T2D.

22 Dec 2010

AIDS patients with serum biomarkers are predisposed to immune reconstitution inflammatory syndrome

A study in this week's PLoS Medicine suggests that AIDS patients with cryptococcal meningitis who start HIV therapy are predisposed to immune reconstitution inflammatory syndrome - an exaggerated inflammatory immune response that kills up to one-third of affected people - if they have biomarkers in their blood showing evidence of a damaged immune system that is not capable of clearing the fungal infection.

22 Dec 2010

Biovest issues FAQ update on BiovaxID personalized cancer vaccine

Biovest International, Inc. today issued the following update in the form of a "Frequently Asked Questions" report in response to the high volume of inquiries received following the Company's recent presentation at the 2010 American Society of Hematology Annual Meeting (ASH 2010) in Orlando, Florida.

21 Dec 2010

Study aims to deliver safer bone marrow transplant treatment strategy in patients with multiple myeloma cancer

A national clinical trial, which opens imminently, will aim to assess the impact of a novel anti-cancer drug in the setting of donor bone marrow transplantation for myeloma.

21 Dec 2010

Investigator to receive AGA-General Mills Bell Institute of Health and Nutrition Research Scholar Award

The American Gastroenterological Association Foundation for Digestive Health and Nutrition announced that Anisa Shaker, MD, is the recipient of the AGA-General Mills Bell Institute of Health and Nutrition Research Scholar Award in Gut Physiology and Health.

21 Dec 2010

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

In notable back-to-back papers appearing in the prestigioous journal Science in October, teams of researchers, one led by Nora Besansky, a professor of biological sciences and a member of the Eck Institute for Global Health at the University of Notre Dame, provided evidence that Anopheles gambiae, which is one of the major mosquito carriers of the malaria parasite in Sub-Saharan Africa, is evolving into two separate species with different traits.

21 Dec 2010

Invitations open for fourth annual Young Investigator Grant for Probiotics Research

Today, the Global Probiotics Council (GPC), a committee formed by Danone and YAKULT HONSHA CO., LTD., announced the launch of the fourth annual Young Investigator Grant for Probiotics Research (YIGPRO). This grant provides two awards, each in the amount of $50,000, to rising young stars. This year's grant focus is on the role of probiotics and gastrointestinal microbiota in health and wellness. Applications will be accepted until February 15, 2011.

21 Dec 2010

Genzyme provides information on peak sale of alemtuzumab for multiple sclerosis

Genzyme Corporation today provided an extensive briefing on the market potential of alemtuzumab for multiple sclerosis at an event for investors and analysts in New York.

21 Dec 2010

Damon Runyon Cancer Research Foundation names first recipients of Frey Award for Breakthrough Scientists

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named the first recipients of the Dale F. Frey Award for Breakthrough Scientists. This new award provides additional funding to scientists completing a prestigious Damon Runyon Fellowship Award who have greatly exceeded the Foundation's highest expectations and are most likely to make paradigm-shifting breakthroughs that transform the way we prevent, diagnose and treat cancer.

21 Dec 2010

Immune System News and Research

Vitamin D levels of newborns appear to predict their risk of respiratory infections

Gold-coated liposomes could make chemotherapy more effective without harmful side effects

Good Clostridia prevents development of allergies and inflammatory bowel disease

Immunization with VLP vaccine results in functional, protective immune responses against RSV

Researchers identify new regulator that play a critical role in B cell development

Certain drugs may block tumor host interactions but do not destroy cancer cells

Combination of antigen and wax nanoparticles improves immunogenicity

Researchers discover protein that suppresses melanoma progression

Time magazine declares NYSCF member as 2010 "Person who Matters" for innovative stem cell research

Therapies to target self-renewing population of chemotherapy-resistant cells needed

Gold nanoparticles show great potential for tumour targeted drug delivery

Altering balance among immune system cells could hold potential for T2D-associated inflammation treatment

AIDS patients with serum biomarkers are predisposed to immune reconstitution inflammatory syndrome

Biovest issues FAQ update on BiovaxID personalized cancer vaccine

Study aims to deliver safer bone marrow transplant treatment strategy in patients with multiple myeloma cancer

Investigator to receive AGA-General Mills Bell Institute of Health and Nutrition Research Scholar Award

Study provides evidence on prevalence of two separate mosquito species which carry malaria parasite

Invitations open for fourth annual Young Investigator Grant for Probiotics Research

Genzyme provides information on peak sale of alemtuzumab for multiple sclerosis

Damon Runyon Cancer Research Foundation names first recipients of Frey Award for Breakthrough Scientists

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