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Study on biodegradable tooth-binding micelles that inhibit Streptococcus mutans biofilm growth

Today, during the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, lead researcher F. Cheni will hold an oral presentation on a research study titled "Biodegradable Tooth-binding Micelles Inhibit Streptococcus mutans (S. mutans) Biofilm Growth."

21 Mar 2011

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

New synchrotron-based imaging technique offers more detailed chemical images

With intensity a million times brighter than sunlight, a new synchrotron-based imaging technique offers high-resolution pictures of the molecular composition of tissues with unprecedented speed and quality. Carol Hirschmugl, a physicist at the University of Wisconsin-Milwaukee (UWM), led a team of researchers from UWM, the University of Illinois at Urbana-Champaign and University of Illinois at Chicago (UIC) to demonstrate these new capabilities.

21 Mar 2011

Smoking during pregnancy increases risk of children becoming smokers too

New research has revealed that prenatal exposure to nicotine increases the vulnerability to nicotine self-administration in adolescent mice. The results support the hypothesis that adolescents with prenatal nicotine exposure are more likely to start smoking earlier than their peers and that they are also more susceptible to the addictive effects of nicotine, especially as a result of stress and peer pressure.

21 Mar 2011

EDMA endorses the campaign against excessive use of salt

EDMA, the European Diagnostic Manufacturers Association, fully endorses the 2011 World Salt Awareness Week theme “Salt and Men’s Health” as the latter reminds that more men than women die prematurely of cardiovascular diseases (CVD).

21 Mar 2011

On health reform law's anniversary: Pros, cons, waivers and state action

News organizations are noting the one-year anniversary of the health law, and covering developments in the states.

21 Mar 2011

$CTI commences pixantrone PIX-R trial in relapsed/refractory diffuse large B-cell lymphoma$

CTI commences pixantrone PIX-R trial in relapsed/refractory diffuse large B-cell lymphoma

Cell Therapeutics, Inc. today announced that it has initiated its randomized pivotal trial of pixantrone for the treatment of relapsed/refractory diffuse large B-cell lymphoma ("DLBCL").

21 Mar 2011

Onset of chronic pain more often reported following a traffic accident

Individuals with poorer health or psychological issues may be prone to developing chronic widespread pain following a traumatic event. This new research, published in Arthritis Care & Research, a peer-reviewed journal of the American College of Rheumatology (ACR), found that the onset of chronic pain was more often reported following a traffic accident than from other physically traumatic triggers.

21 Mar 2011

Scots drinking too much: Report

According to a survey by Britains’s NHS, people of Scotland are drinking too much. Deaths related to alcohol are at an all time high in the country. The survey finds that Scots are consuming an additional 1.2 litres of pure alcohol per year. Alcohol-related deaths and hospital admissions are four times higher since the 1980’s. A recent report has also showed that alcohol related deaths were six-fold higher among the poor people.

21 Mar 2011

Drug delivery breakthrough for Alzheimer’s disease

Till date all attempts to get drugs into the brain were countered by the blood-brain barrier - the natural defense against potentially harmful chemicals floating around the body. However this new finding from a team from University of Oxford shows that now scientists have successfully switched off a gene implicated in Alzheimer’s disease in the brains of mice by exploiting tiny particles naturally released by cells, called exosomes.

21 Mar 2011

Asthma an diabetes go hand in hand: Research

A new study has found that people with asthma may have a higher risk of developing diabetes and heart disease. The study looked at the relationship between asthma and four other inflammatory conditions.

21 Mar 2011

Ibuprofen - painkiller toxicity warning

In a recent development, doctors have warned regarding the possibly toxicities of common pain killer Ibuprofen adding that it can lead to a potentially fatal condition which can be triggered, in rare cases, by even a standard dose. The condition in question is called renal tubular acidosis (RTA). The research is published in the Medical Journal of Australia.

21 Mar 2011

Intensive weekends: Higher death rates at ICUs over weekends

The study spanned over eight-years and 245,000 admissions to 41 intensive care units throughout Australia to come to this conclusion. It is published in The Medical Journal of Australia. It also showed that this pattern persisted even after accounting for severity of illness.

21 Mar 2011

Potential bias seen in informed consent language when describing trials, say researchers

When presented with different terms to describe a clinical trial, parents were far more likely to consent to enroll their child if it was called a "research study" than if it was called a "medical experiment" or a "research project," in large part because they perceived the former as safer, even though that was not necessarily the case, according to a report in IRB: Ethics & Human Research.

19 Mar 2011

Researcher to present study on validation of salivary-biomarkers for pSS patients

Saturday, March 19, during the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, lead researcher A.N.M. Nazmul-Hossaini will hold an oral presentation on a study titled "Validation of Salivary-Biomarkers for Sj-gren's Syndrome Detection in US Population."

19 Mar 2011

Flexibility key word at Senate hearing on state exchanges

State officials from different political perspectives expressed interest in establishing health insurance exchanges, and an administration official promised "a wide berth" in how states choose to construct parts of the reform law.

19 Mar 2011

Insight into hereditary diseases

Hereditary diseases such as epilepsy or various coordination disorders may be caused by changes in nerve cells of the cerebellum, which do not set in until after birth. This is reported by Bochum's neuroscientists in the Journal of Neuroscience.

19 Mar 2011

U-M professor shows how plasticity of brain restores critical functions related to learning, memory

When Geoffrey Murphy, Ph.D., talks about plastic structures, he's not talking about the same thing as Mr. McGuire in The Graduate. To Murphy, an associate professor of molecular and integrative physiology at the University of Michigan Medical School, plasticity refers to the brain's ability to change as we learn.

19 Mar 2011

House GOP targets CLASS Act during subcommittee hearing

Republicans on the panel took issue with the 2012 start-up funding sought by the Department of Health and Human Services, though the long-term care program is one part of the health law Democrats have made clear they are open to refining.

19 Mar 2011

Symposium discusses about novel approaches to bacterial caries management

Saturday, March 19, during the 89th General Session & Exhibition of the International Association for Dental Research, held in conjunction with the 40th Annual Meeting of the American Association for Dental Research and the 35th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "Novel Approaches to Bacterial Caries Management: an Efficacious Solution in View?" will take place.

19 Mar 2011