Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Cancer uses immature immune cells as support system for successful metastasis, study shows

More typically, these immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread.

6 Apr 2017

Supercomputers reveal how cell membranes control shape and function of cancer-causing protein

Two biophysicists from Case Western Reserve University School of Medicine have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein.

4 Apr 2017

Researchers identify biomarker for likely aggressive, early-stage breast cancers

The one-size-fits-all approach to early stage breast cancer creates a paradox: Millions of dollars are spent on unnecessary surgeries and radiation to treat women with low-risk 'in situ' lesions, an estimated 85% of which would never progress to invasive cancers.

4 Apr 2017

ANGLE’s Parsortix system could help predict metastasis in prostate cancer

ANGLE plc, the specialist medtech company, is delighted to announce that researchers from the Barts Cancer Institute, Queen Mary University of London, have presented new results at the World CDx Europe 2017 conference in London of their work with ANGLE’s Parsortix system in prostate cancer.

31 Mar 2017

Combining anticancer drug with antirheumatic produces improved effects against tumors

Scientists at EPFL and NTU have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy.

30 Mar 2017

Study shows inhibition of transgelin prevents vasculogenic mimicry in breast cancer

An article published in Experimental Biology and Medicine identifies a new signaling pathway involved in breast cancer cell growth. The study, led by Dr. Chan-Wha Kim, from the Department of Biotechnology at Korea University in Seoul, reports that inhibition of the actin-binding protein transgelin prevents vasculogenic mimicry (VM), a process that provides tumor cells with the nutrients required for growth.

29 Mar 2017

Rarely studied faulty USF3 gene may predispose individuals to thyroid cancer

Charis Eng, M.D., Ph.D., of Cleveland Clinic and her team have discovered that a faulty, rarely studied gene called USF3 may predispose individuals to thyroid cancer. They recently published this discovery in Human Molecular Genetics.

29 Mar 2017

Major grant funds research effort that seeks to understand complexity of invasive cancer

A $9.5 million, five-year grant from the National Cancer Institute (NCI) will fund an intensive multidisciplinary research effort that seeks to better understand how cancer cells reach an aggressive state and begin to damage surrounding tissue.

25 Mar 2017

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat.

24 Mar 2017

Researchers identify odorant troenan that can inhibit colorectal cancer growth

Growth of colorectal cancer cells can be inhibited with the odorant troenan. This is reported by the research team headed by Prof Dr Dr Dr habil. Hanns Hatt and Dr Lea Weber from Ruhr-Universität Bochum in the journal "PLOS One".

23 Mar 2017

Machine learning helps researchers uncover cellular control networks

The flow of information between cells in our bodies is exceedingly complex: sensing, signaling, and influencing each other in a constant flow of microscopic engagements. These interactions are critical for life, and when they go awry can lead to the illness and injury.

22 Mar 2017

Simple blood test may soon eliminate need for invasive procedures to detect, monitor cancer

Doctors may soon be able to detect and monitor a patient's cancer with a simple blood test, reducing or eliminating the need for more invasive procedures, according to Purdue University research.

21 Mar 2017

Better understanding of pre-metastatic niches could lead to new preventive therapies

Metastasis is the major cause of cancer-related death and its appearance remains a phenomenon that is difficult to predict and manage.

17 Mar 2017

The Sohn Conference Foundation funds research to advance understanding of how pediatric cancer metastasizes

The Sohn Conference Foundation today unveiled the Sohn Collaborative for Liquid Biopsy at Weill Cornell Medicine to develop a blood test that will predict how cancer spreads in both children and adults.

17 Mar 2017

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma — the most common head and neck cancer and the second-most common skin cancer, according to a new study by cancer researchers at the UCLA School of Dentistry.

10 Mar 2017

Combination therapy that targets immune-busting cells effective in treating advanced prostate cancer

Advanced prostate cancer resistant to castration therapy appears to respond well to a combination of immune checkpoint blockades and treatments that target certain immune-busting cells commonly associated with poor patient prognosis and therapy resistance.

10 Mar 2017

Metastasis News and Research

Further Reading

Cancer uses immature immune cells as support system for successful metastasis, study shows

Supercomputers reveal how cell membranes control shape and function of cancer-causing protein

Researchers identify biomarker for likely aggressive, early-stage breast cancers

ANGLE’s Parsortix system could help predict metastasis in prostate cancer

Combining anticancer drug with antirheumatic produces improved effects against tumors

Study shows inhibition of transgelin prevents vasculogenic mimicry in breast cancer

Rarely studied faulty USF3 gene may predispose individuals to thyroid cancer

Major grant funds research effort that seeks to understand complexity of invasive cancer

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

Researchers identify odorant troenan that can inhibit colorectal cancer growth

Machine learning helps researchers uncover cellular control networks

Simple blood test may soon eliminate need for invasive procedures to detect, monitor cancer

Better understanding of pre-metastatic niches could lead to new preventive therapies

The Sohn Conference Foundation funds research to advance understanding of how pediatric cancer metastasizes

Targeting cancer stem cells may be effective way to prevent spread of squamous cell carcinoma

Combination therapy that targets immune-busting cells effective in treating advanced prostate cancer

Researchers discover unexpected link between brain development and tumor invasion

Vitamin C can be used to target and kill cancer stem cells, research finds

Diabetes medication could be effective therapy for aggressive type of breast cancer

Notch activity of cells in tumor microenvironment can influence cancer metastases, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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