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Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

A randomized controlled trial assesses the efficacy and safety of high-dose convalescent plasma in the treatment of severe COVID-19.

1 Feb 2022

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Neural stem cells (NSCs) engineered by Northwestern Medicine investigators used in combination with the HER2 inhibitor drug tucatinib improved survival in mice with HER2-positive breast cancer brain metastases, according to findings published in Proceedings of the National Academy of Sciences.

1 Feb 2022

Open-label placebo shows promise as therapy for disorders of gut-brain interaction in children

Pain-predominant disorders of gut-brain interaction (DGBIs) in children - such as functional abdominal pain (FAP) and irritable bowel syndrome (IBS) - can lead to disabling symptoms, poor quality of life and high use of health care resources.

31 Jan 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.

28 Jan 2022

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age.

28 Jan 2022

New trial tests the effectiveness of hyperimmune immunoglobulin for hospitalized COVID-19 patients

This scanning electron microscope image shows SARS-CoV-2 (round gold particles) emerging from the surface of a cell cultured in the lab. SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19.NIAID

28 Jan 2022

Daily supplementation with vitamin D and fish oil may lower the risk of autoimmune disease

Taking daily vitamin D supplements - or a combination of vitamin D and omega-3 fish oil - appears to carry a lower risk of developing autoimmune disease, with a more pronounced effect after two years, finds a trial of older US adults published by The BMJ today.

27 Jan 2022

Study explores how cannabis use affects driving performance

The steady rise in the use of cannabis - 18 states have legalized recreational use, 13 have decriminalized its use and 36 have medical cannabis laws - has provoked myriad questions and concerns about public health implications, including how cannabis may affect the abilities, real and perceived, of drivers under the influence.

26 Jan 2022

Does remdesivir reduce mortality in moderately ill hospitalized patients with COVID-19?

A team of researchers performed a meta-analysis to investigate the use of remdesivir in the treatment of COVID-19.

26 Jan 2022

Hospitalized COVID-19 patients may derive modest benefit from convalescent plasma, study shows

Transfusions of blood plasma donated by people who have recovered from COVID-19 may help patients hospitalized with the virus, a new international study shows.

25 Jan 2022

Humoral correlate of protection for SARS-CoV-2 may reduce COVID-19 infection risk

In a new study, a team of researchers reviewed the published literature to find evidence for humoral SARS-CoV-2 correlate of protection (CoP).

25 Jan 2022

Causal impact of spontaneous relaxation of social distancing practices on spread of SARS-CoV-2 in US

The purpose of a recent study was to examine the causal impact of a spontaneous relaxation of social distancing measures on the spread of SARS-CoV-2.

24 Jan 2022

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Considerable controversy surrounds race-based algorithms in medicine - such as an adjustment for Black race in equations that estimate individuals' kidney function. A new study in CJASN has examined the impact of changes to these equations on the inclusion of Black participants in kidney disease–related clinical trials, and on the results of such trials.

24 Jan 2022

Echinacea as a potential force against coronavirus infections

A new review identified clinical studies evaluating coronavirus infections in the context of Echinacea administration and assessed preventive and therapy advantages against COVID-19.

21 Jan 2022

New opportunity to induce remission of peanut allergy in young children through oral immunotherapy

A clinical trial funded by the National Institutes of Health has found that giving peanut oral immunotherapy to highly peanut-allergic children ages 1 to 3 years safely desensitized most of them to peanut and induced remission of peanut allergy in one-fifth. The immunotherapy consisted of a daily oral dose of peanut flour for 2.5 years.

21 Jan 2022

Oral supplement appears to promote muscle endurance and mitochondrial health in humans

An oral supplement intended to stimulate a natural body process appears to promote muscle endurance and mitochondrial health in humans.

20 Jan 2022

Study shows efficacy, safety of oral immunotherapy in one- to three-year-olds with peanut allergy

The majority of young children treated with peanut immunotherapy achieved desensitization after two and a half years of treatment, and one in five remained in remission 26 weeks after treatment ended, according to a randomized controlled trial published in The Lancet.

20 Jan 2022

Placebo News and Research

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

Neural stem cells plus HER2 inhibitor drug improve survival in mice with metastatic cancer

Open-label placebo shows promise as therapy for disorders of gut-brain interaction in children

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

Study investigates how vitamin D or omega fatty acids may affect rates of autoimmune diseases

New trial tests the effectiveness of hyperimmune immunoglobulin for hospitalized COVID-19 patients

Daily supplementation with vitamin D and fish oil may lower the risk of autoimmune disease

Study explores how cannabis use affects driving performance

Does remdesivir reduce mortality in moderately ill hospitalized patients with COVID-19?

Hospitalized COVID-19 patients may derive modest benefit from convalescent plasma, study shows

Humoral correlate of protection for SARS-CoV-2 may reduce COVID-19 infection risk

Causal impact of spontaneous relaxation of social distancing practices on spread of SARS-CoV-2 in US

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Echinacea as a potential force against coronavirus infections

New opportunity to induce remission of peanut allergy in young children through oral immunotherapy

Oral supplement appears to promote muscle endurance and mitochondrial health in humans

Study shows efficacy, safety of oral immunotherapy in one- to three-year-olds with peanut allergy

Researchers compare two psychotherapies used for treating veterans with PTSD

"Nocebo effect" accounts for 76% of all adverse events in the COVID-19 vaccine trial group

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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