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Clinical severity of SARS-CoV-2-Omicron infection found to be lower than Delta infection

Researchers evaluated the severity of SARS-CoV-2cc infection by the Omicron variant compared to the Delta variant.

21 Mar 2022

SARS-CoV-2 infection found to reduce fetal lung volume as assessed by MRI

Researchers evaluated the impact of SARS-CoV-2 infection in gestational women on fetal pulmonary development using magnetic resonance imaging.

21 Mar 2022

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

A team of scientists from Turkey has recently evaluated the diversity and composition of gut microbiota in children diagnosed with multisystem inflammatory syndrome (MIS-C) and acute coronavirus disease 2019 (COVID-19). They have observed significant alteration in the gut microbiota composition in children with MIS-C. These changes are associated with autoimmunity, metabolic dysfunction, and obesity.

21 Mar 2022

Low levels of SARS-CoV-2 viremia associated with ‘COVID placentitis’ and stillbirths

Researchers hypothesize that patients with COVID placentitis were more likely to contract viremia.

20 Mar 2022

Response to COVID-19 boosters in seronegative multiple sclerosis patients

Researchers report humoral T-cell responses in seronegative MS patients after receiving a third COVID-19 booster vaccine dose.

20 Mar 2022

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Researchers assessed the impact of recombinant accessory protein-deficient severe acute respiratory syndrome coronavirus 2 immunization against SARS-CoV-2 transmission and disease severity.

18 Mar 2022

Presence of zoonotic pathogens in wildlife market for human consumption in Laos

Researchers from different countries examined various animal species from wildlife trade sites to detect the presence of zoonotic pathogens in Laos, South East Asia.

18 Mar 2022

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Researchers evaluated the underlying cellular mechanisms of SARS-CoV-2-induced olfactory epithelium damage in golden Syrian hamsters.

18 Mar 2022

Characteristics of super-spreaders of novel coronaviruses

Researchers conducted a systematic review to evaluate the characteristics of super-spreaders of three novel coronaviruses that caused SARS, MERS, and COVID-19.

18 Mar 2022

Duration of Omicron variant shedding isolated from upper respiratory samples collected from the reported case-patients in Japan

Researchers conducted a retrospective analysis to evaluate the duration of the SARS-CoV-2 Omicron variant virus shedding

18 Mar 2022

SARS-CoV-2 burden and transmission in one rural and one urban community in South Africa

Researchers conducted a prospective household cohort study of COVID-19, influenza, and respiratory syncytial virus community burden, viral interaction, and transmission dynamics, called PHIRST-C study in South Africa.

18 Mar 2022

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

Researchers investigated whether small airway diseases are present following acute SARS-CoV-2 infection.

18 Mar 2022

COVID-19-related hospitalization among infants and young children in the US

Researchers investigated COVID-19-associated hospitalization among children and infants aged zero to four years in the United States during March 2020 and February 2022.

18 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Researchers used molecular surveillance to identify cases of co-infection with SARS-CoV-2 variants of concern Delta and Omicron reported in Argentina during December 2021 and January 2022.

17 Mar 2022

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection.

17 Mar 2022

Researchers evaluate predictors for mortality in hospitalized COVID-19 patients

Researchers identified independent factors associated with early and late deaths in hospitalized COVID-19 patients.

17 Mar 2022

Biomarkers to identify SARS-CoV-2 patients requiring invasive mechanical ventilation

Researchers evaluated biomarkers that could help identify COVID-19 patients needing invasive mechanical ventilation.

17 Mar 2022

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers constructed a novel fusion inhibitor−based recombinant protein, referred to as 5−Helix, to block SARS-CoV-2 spike-mediated cell-cell fusion.

17 Mar 2022

Researchers develop extraction-free saliva RT-LAMP assay for workplace surveillance of SARS-CoV-2

Researchers developed a saliva-based, extraction-free reverse transcription loop-mediated isothermal amplification workflow for SARS-CoV-2 detection.

17 Mar 2022

Polymerase News and Research

Clinical severity of SARS-CoV-2-Omicron infection found to be lower than Delta infection

SARS-CoV-2 infection found to reduce fetal lung volume as assessed by MRI

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

Low levels of SARS-CoV-2 viremia associated with ‘COVID placentitis’ and stillbirths

Response to COVID-19 boosters in seronegative multiple sclerosis patients

Study evaluates COVID-19 vaccination with recombinant accessory protein-deficient SARS-CoV-2

Presence of zoonotic pathogens in wildlife market for human consumption in Laos

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Characteristics of super-spreaders of novel coronaviruses

Duration of Omicron variant shedding isolated from upper respiratory samples collected from the reported case-patients in Japan

SARS-CoV-2 burden and transmission in one rural and one urban community in South Africa

Study shows small airways disease with the presence of air trapping is a long-lasting sequelae of SARS-CoV-2 infection

COVID-19-related hospitalization among infants and young children in the US

Novel screening method detects new N501T SARS-CoV-2 variant

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers evaluate predictors for mortality in hospitalized COVID-19 patients

Biomarkers to identify SARS-CoV-2 patients requiring invasive mechanical ventilation

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers develop extraction-free saliva RT-LAMP assay for workplace surveillance of SARS-CoV-2

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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