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ECOG-ACRIN and Caris Life Sciences launch collaborative cancer research initiative

ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and Caris Life Sciences(Caris) announced today a multi-year research collaboration wherein Caris is pairing its highly sophisticated and comprehensive genomic, transcriptomic and proteomic profiling, advanced artificial intelligence (AI) and machine learning algorithms with ECOG-ACRIN's immense research capabilities.

24 Oct 2024

Study reveals hormone receptors' role in brain health and neuroprotection

In a comprehensive review published in the October 2024 issue of Genomic Psychiatry, researchers have unveiled crucial insights into how two types of hormone receptors collaborate to maintain brain health and potentially prevent neurodegenerative diseases.

24 Oct 2024

Semaglutide may lower Alzheimer's risk in type 2 diabetes patients

Researchers at the Case Western Reserve School of Medicine have found that, when compared to seven other anti-diabetic drugs, semaglutide, a popular diabetes and weight-loss drug, may lower the risk of Alzheimer's disease in people with type 2 diabetes (T2D).

24 Oct 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

Researchers identify mechanism of immune suppression in ovarian cancer

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack—blocking the energy supply T cells depend on. The study, published Oct. 23 in Nature, points toward a promising new immunotherapy approach for ovarian cancer, which is notoriously aggressive and hard to treat.

24 Oct 2024

HER2-postive breast cancer drugs show promise for bile duct cancer treatment

Drugs designed to target HER2-postive breast cancer could also benefit some patients with bile duct cancer, according to results of a patient trial to be presented on Thursday at the 36th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain.

23 Oct 2024

Researchers discover how ovarian tumors cripple immune cells

Weill Cornell Medicine researchers have discovered a mechanism that ovarian tumors use to cripple immune cells and impede their attack - blocking the energy supply T cells depend on.

23 Oct 2024

Rise in weight-management glucose-lowering drug prescriptions in type 1 diabetes patients

From 2010 to 2023, GLP-1RAs and SGLT2 inhibitors saw rising prescriptions in type 1 diabetes, particularly for patients with obesity and cardiorenal risks.

23 Oct 2024

Study connects brain volume variations with genetic risk factors for Parkinson’s disease and ADHD

Unprecedented genome analysis reveals genetic links between brain structure and disorders like Parkinson's and ADHD, paving the way for innovative treatments.

23 Oct 2024

Advancements in antibody-drug conjugates transform cancer therapy

Antibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines the precision of monoclonal antibodies with the potency of cytotoxic drugs.

22 Oct 2024

Study highlights life-saving potential of access to effective obesity treatments

Expanding access to new, highly effective weight-loss medications could prevent more than 40,000 deaths a year in the United States, according to a new study led by researchers at Yale School of Public Health and the University of Florida.

22 Oct 2024

Structural biology reveals secrets of DEV phage infection

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

22 Oct 2024

New drug shows promise for motor neurone disease treatment

A pioneering study published in the International Journal of Molecular Sciences by researchers at Durham University has revealed promising results for a new treatment targeting motor neurone disease (MND).

22 Oct 2024

New research reveals GPR31's role in immune response to gut infections

Researchers from Osaka University discover that the GPR31 path in 'gut surveillance' cells detects bacterial metabolites and triggers immune responses, opening new possibilities for drug development, vaccines, and probiotics to fight infections.

22 Oct 2024

New antibody targets cancer-causing HER2 mutations

For some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and causing cancer.

22 Oct 2024

Diabetes drugs may reduce risk of opioid overdose and alcohol intoxication

Researchers examine the association between prescriptions of diabetes drugs and the incidence of alcohol intoxication and opioid overdose.

22 Oct 2024

New CAR T cells offer controlled treatment for solid tumors

Ludwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR) T cells - a type of cancer immunotherapy - that can be switched on to varying degrees of intensity and then switched off on demand with existing drugs.

21 Oct 2024

New PET scan effectively detects benign insulinomas in the pancreas

A new PET scan reliably detects benign tumors in the pancreas, according to research led by Radboud university medical center.

21 Oct 2024

New guidelines focus on preventing first strokes through healthy living

Healthy lifestyle behaviors, such as good nutrition, smoking cessation and being physically active, along with routine health screenings and managing risk factors for cardiovascular disease and stroke with medication, can help prevent individuals from having a first stroke.

21 Oct 2024

It's official! Men and women experience and manage pain differently

Researchers uncover sex-specific pain management mechanisms, revealing men rely on endogenous opioids while women use alternative pathways for pain relief.

21 Oct 2024