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Phase 3 trial of ataluren commences

PTC Therapeutics, Inc. (PTC) today announced the initiation of a Phase 3 trial of ataluren (formerly PTC124(R)), an investigational protein restoration therapy in patients with nonsense mutation cystic fibrosis (nmCF).

11 Sep 2009

Drug manufacturers are seeking out needle-free systems

Many of the novel biopharmaceutical drugs developed now can only be delivered by injection, and this has biologic manufacturers seeking out the most patient-friendly options, including needle-free systems.

11 Sep 2009

Second-hand tobacco smoke exposure results in NAFLD

A team of scientists at the University of California, Riverside has found that even second-hand tobacco smoke exposure can result in nonalcoholic fatty liver disease (NAFLD), a common disease and rising cause of chronic liver injury in which fat accumulates in the liver of people who drink little or no alcohol.

11 Sep 2009

Ascent Therapeutics demonstrates Pepducin efficacy

Ascent Therapeutics announced today that the Company has demonstrated efficacy in preclinical models in two Pepducin projects. One of the projects targets CXCR4, a key regulator of stem cell and inflammatory cell homeostasis. A second project has yielded the first potent Pepducin agonists for an undisclosed cardiovascular target.

11 Sep 2009

New World Health Organization data emphasizes on two leading causes of pneumonia

New World Health Organization data to be published in this week's edition of The Lancet will shed new light on two leading causes of pneumonia, the world’s leading killer of children under age 5, both globally and within specific countries.

11 Sep 2009

TrKA and CCM2 combination results in pediatric tumour regression

Why are some pediatric cancers able to spontaneously regress? Prof. Michael Fainzilber and his team of the Weizmann Institute's Biological Chemistry Department seem to have unexpectedly found part of the answer. Further research towards a better understanding of the mechanism of action might hopefully lead, in the future, to the development of drugs that will be able to induce regression of certain tumors.

10 Sep 2009

CytRx granted patent for molecular chaperone amplifier drug candidate

CytRx Corporation, a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, today announced that it has been granted a key patent by the European Patent Office that covers through 2024 the use of its orally available molecular chaperone amplifier drug candidate arimoclomol for the treatment or prevention of neurodegenerative diseases of the central nervous system (CNS).

10 Sep 2009

Endothelin research update to be presented at APS' 11th International Conference

Recent research to block the effects of endothelin, a powerful substance that constricts blood vessels and stimulates cell growth, has led to successful treatment of pulmonary arterial hypertension and provides hope for treating other chronic diseases.

10 Sep 2009

Aushon BioSystems completes construction of new laboratory and manufacturing facility

Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis, announced today that it has completed the renovation and expansion of its Billerica, MA corporate headquarters.

10 Sep 2009

Research on the role of microRNAs in cellular processes

RNAs, serving as a mere intermediary between DNA and proteins, were long regarded as a poor relation by researchers, attracting little interest. However, following the discovery of small RNAs known as microRNAs, they have increasingly been moving into the limelight. MicroRNAs bind to messenger RNA (mRNA), thereby regulating the translation of genes into proteins.

10 Sep 2009

New Influenza A/H1N1 detection kit launched

QIAGEN, today announced both the launch of a new Influenza A/H1N1 test and several updates to its activities in providing solutions for the global surveillance of the swine flu pandemic. QIAGEN’s new kit enables both the highly sensitive and specific detection of the novel Influenza A/H1N1, the virus that causes “swine flu”, as well as of all other known Influenza A and B virus strains.

10 Sep 2009

Genomic technologies to improve wine production techniques

While the art of fine winemaking is a beautiful thing, winemakers are increasingly turning to the power of science to give them the tools they need to ensure a high quality pour each and every time.

10 Sep 2009

Aperio Technologies forges alliance with HistoRx to provide an integrated whole-slide imaging system

Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, and HistoRx, Inc., (HistoRx), a leader in the emerging field of tissue-based assays for targeted patient treatment, have entered into a partnership to provide an integrated solution for whole-slide imaging with fluorescence.

10 Sep 2009

University of California receives $3.5 million grant from NIDA for AIDS vaccine research

The National Institute on Drug Abuse (NIDA) has awarded a $3.5 million grant for AIDS vaccine research to Phillip Berman, professor and chair of biomolecular engineering at the Jack Baskin School of Engineering at the University of California, Santa Cruz.

9 Sep 2009

aTyr Pharma expands intellectual property portfolio, receives its fifteenth patent

aTyr Pharma announced today that the US Patent office has issued patent US 7,572,452 B2, titled "Method for Stimulating Wound Healing." aTyr Pharma is the sole assignee of this patent, and Professor Sunghoon Kim, a scientific co-founder of aTyr Pharma, is the inventor.

9 Sep 2009

Research study on memory formation and storage process in the human brain

A new study that was carried out at the University of Haifa has identified another component in the chain of actions that take place in the neurons in the process of forming memories. This discovery joins a line of findings from previous studies that together provide a better understanding of the most complex processes in nature - the process of memory formation and storage in the human brain. The new study has been published in the prestigious Journal of Neuroscience.

9 Sep 2009

Molecular mechanism responsible for transition of non-invasive breast cancer into invasive disease discovered

Active, but non-invasive breast cancer is set free to roam as invasive breast cancer when an overexpressed protein converts it to a different cell type, scientists at The University of Texas M. D. Anderson Cancer Center report in the Sept. 9 issue of the journal Cancer Cell.

9 Sep 2009

New findings may help identify treatments for diabetes and hyperinsulinemia

By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. The mechanism involves a protein called ankyrin, which UI researchers previously linked to potentially fatal human heart arrhythmias.

9 Sep 2009

Thermo Fisher Scientific receives Ringier Technology Innovation Award

Thermo Fisher Scientific Inc. (NYSE: TMO), the world leader in serving science, today announced that it has received a Ringier Technology Innovation Award for its role in helping Chinese laboratories quickly develop melamine detection capabilities following the discovery of melamine-tainted milk and infant formula in China. The award was presented by Ringier Trade Publishing, which publishes China's leading food industry magazine, Food Manufacturing Journal.

From Thermo Fisher Scientific Inc. 9 Sep 2009

Laureate Pharma and Neoprobe sign manufacturing agreement

Neoprobe Corporation (OTCBB: NEOP), a diversified developer of innovative oncology surgical and diagnostic products, and Laureate Pharma, Inc., a full-service biopharmaceutical development and protein production company, today announced that they have entered into a Biopharmaceutical Development and Manufacturing Agreement.

9 Sep 2009

G Protein News and Research

Phase 3 trial of ataluren commences

Drug manufacturers are seeking out needle-free systems

Second-hand tobacco smoke exposure results in NAFLD

Ascent Therapeutics demonstrates Pepducin efficacy

New World Health Organization data emphasizes on two leading causes of pneumonia

TrKA and CCM2 combination results in pediatric tumour regression

CytRx granted patent for molecular chaperone amplifier drug candidate

Endothelin research update to be presented at APS' 11th International Conference

Aushon BioSystems completes construction of new laboratory and manufacturing facility

Research on the role of microRNAs in cellular processes

New Influenza A/H1N1 detection kit launched

Genomic technologies to improve wine production techniques

Aperio Technologies forges alliance with HistoRx to provide an integrated whole-slide imaging system

University of California receives $3.5 million grant from NIDA for AIDS vaccine research

aTyr Pharma expands intellectual property portfolio, receives its fifteenth patent

Research study on memory formation and storage process in the human brain

Molecular mechanism responsible for transition of non-invasive breast cancer into invasive disease discovered

New findings may help identify treatments for diabetes and hyperinsulinemia

Thermo Fisher Scientific receives Ringier Technology Innovation Award

Laureate Pharma and Neoprobe sign manufacturing agreement

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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