Immune System News and Research

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Children missing out on in battle against TB

The number of children diagnosed with tuberculosis only represents the tip of the iceberg, according to the University of Sydney’s Associate Professor Ben Marais, a specialist in childhood tuberculosis writing in the latest issue of The New England Journal of Medicine.

25 Jul 2012

First Edition: July 25, 2012

Today's headlines detail new Congressional Budget Office health law estimates that reflect the Supreme Court's decision on the Medicaid expansion.

25 Jul 2012

Human neutrophil peptide 1 effectively prevents HIV entry into cells in multiple ways

Human defensins, aptly named antimicrobial peptides, are made in immune system cells and epithelial cells (such as skin cells and cells that line the gut). One of these peptides, human neutrophil peptide 1, under certain circumstances hinders HIV infection, but exactly how it works remains unclear.

25 Jul 2012

Study uncovers pathways by which yoga impacts biological processes

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer's and dementia. Now they know why.

25 Jul 2012

NBTI participates in ICT-107 phase II trial for glioblastoma multiforme

Researchers at Northwestern Brain Tumor Institute (NBTI) are seeking to understand if a vaccine made from a patient's own blood cells may slow the growth of a type of brain tumor.

25 Jul 2012

Giving patients a new immune system can cure Crohn's disease

Researchers at Fred Hutchinson Cancer Research Center have opened a clinical trial to test the theory that giving a patient a new immune system can cure severe cases of Crohn's disease, a chronic inflammatory condition of the gastrointestinal tract.

25 Jul 2012

Mercyhurst expert addresses FDA's recent ban on Bisphenol-A

The FDA says baby bottles and sippy cups can no longer contain Bisphenol-A (BPA), an endocrine disruptor that mimics estrogen. But what about the hundreds of other plastic items, from water bottles to dental sealants, containing BPA?

25 Jul 2012

Views on AIDS: The benefits of male circumcision; A more optimistic battle; The need to focus on high-impact prevention strategies

A selection of editorials and op-eds from around the country that focus on the campaign to eradicate HIV.

25 Jul 2012

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

White blood cells called neutrophils, which are the first line of defense against infection, play an unexpected role by boosting antibody production, according to research led by Mount Sinai School of Medicine. The findings suggest neutrophils have multiple roles within the immune system and function at levels previously unknown to the scientific community. The research, published in Nature Immunology, provides groundbreaking insight into possible new approaches in vaccine development for blood-borne infections and HIV.

25 Jul 2012

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

BioCryst Pharmaceuticals, Inc. announced favorable 52-week safety results and sustained efficacy from the extension phase of its randomized Phase 2b trial of ulodesine (BCX4208) added to allopurinol in patients with gout who had failed to reach the serum uric acid (sUA) therapeutic goal of <6 mg/dL on allopurinol alone, as well as positive Phase 2 safety results in patients with mild to moderate renal impairment.

25 Jul 2012

International Antiviral Society-USA calls for treatment for all who test HIV-positive

"An international group of scientists on Sunday called for all adults who test positive for HIV to be treated with antiretroviral drugs right away rather than waiting for their immune systems to weaken," Agence France-Presse reports.

24 Jul 2012

Study represents new use of bone marrow transplantation

24 Jul 2012

Pancreatic cancer risk may be lowered by high dietary antioxidant intake

Increasing dietary intake of the antioxidant vitamins C, E, and selenium could help cut the risk of developing pancreatic cancer by up to two thirds, suggests research published online in the journal Gut.

24 Jul 2012

Scientists identify mechanisms by which GLP-1 protects against kidney disease, diabetes

Scientists at Joslin Diabetes Center have identified biological mechanisms by which glucagon-like peptide-1 (GLP-1), a gut hormone, protects against kidney disease, and also mechanisms that inhibit its actions in diabetes.

24 Jul 2012

PAMAM G-3 actually prevents activation of the process that leads to thrombosis

A compound that mops up debris of damaged cells from the bloodstream may be the first in a new class of drugs designed to address one of medicine's most difficult challenges -- stopping the formation of blood clots without triggering equally threatening bleeding.

24 Jul 2012

Oral immunotherapy hope for egg allergy in children

Oral immunotherapy for the treatment of egg allergy results in desensitization with long-lasting results in three-quarters of children, show study findings.

23 Jul 2012

Egg allergy treatment for children: an interview with Dr Robert Wood

The tendency to get allergies is a fairly general one, which is mostly inherited – it tends to run in families. There are several foods that are most common for children to become allergic to: milk, egg and peanuts in most countries are the most common food allergies.

23 Jul 2012

All adult patients with HIV should be offered ART: International Antiviral Society-USA panel

Included in the 2012 International Antiviral Society-USA panel recommendations for human immunodeficiency virus (HIV) patient care is that all adult patients, regardless of CD4 cell count, should be offered antiretroviral therapy (ART), according to an article in the July 25 issue of JAMA, a theme issue on HIV/AIDS.

23 Jul 2012

Study addresses African patients’ attitudes toward HIV antiretroviral therapy

An ongoing clinical study in rural Uganda, begun in 2011, suggests that many people infected with HIV/AIDS would take antiretroviral drugs if they were available to them—even before they developed symptoms from the disease.

23 Jul 2012

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

The elevated risk of cardiovascular disease seen in patients infected with HIV appears to be associated with increased inflammation within the arteries, according to a study that will appear in a special issue of JAMA published in conjunction with the International AIDS Conference.

23 Jul 2012

Immune System News and Research

Children missing out on in battle against TB

First Edition: July 25, 2012

Human neutrophil peptide 1 effectively prevents HIV entry into cells in multiple ways

Study uncovers pathways by which yoga impacts biological processes

NBTI participates in ICT-107 phase II trial for glioblastoma multiforme

Giving patients a new immune system can cure Crohn's disease

Mercyhurst expert addresses FDA's recent ban on Bisphenol-A

Views on AIDS: The benefits of male circumcision; A more optimistic battle; The need to focus on high-impact prevention strategies

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout

International Antiviral Society-USA calls for treatment for all who test HIV-positive

Study represents new use of bone marrow transplantation

Pancreatic cancer risk may be lowered by high dietary antioxidant intake

Scientists identify mechanisms by which GLP-1 protects against kidney disease, diabetes

PAMAM G-3 actually prevents activation of the process that leads to thrombosis

Oral immunotherapy hope for egg allergy in children

Egg allergy treatment for children: an interview with Dr Robert Wood

All adult patients with HIV should be offered ART: International Antiviral Society-USA panel

Study addresses African patients’ attitudes toward HIV antiretroviral therapy

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

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