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Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Poor sleep associated with different durations of compromised cardiovascular health

Poor sleep could lead to between two and seven years worth of heightened heart disease risk and even premature death, according to a new study led by researchers at the University of Sydney in collaboration with Southern Denmark University.

8 Mar 2023

Newly diagnosed atrial fibrillation linked to modestly elevated risk of dementia

In a large study of diverse adults in California, individuals with newly diagnosed atrial fibrillation, or an irregular heart rhythm, had a modestly elevated risk of developing dementia.

8 Mar 2023

Reentry programs to help former prisoners obtain health care are often underused

When Matthew Boyd was released from a Georgia state prison in December 2020, officials sent him home without medicines he uses to manage chronic heart and lung conditions and high blood pressure, he said.

8 Mar 2023

Newly identified bone matrix protein may help treat osteosarcoma

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

8 Mar 2023

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart "tissue-on-a-chip" specimens into space as early as March.

7 Mar 2023

Additive effects of genetic, socioeconomic factors account for the prevalence of type 2 diabetes and obesity

New research led by investigators at Massachusetts General Hospital, a founding member of Mass General Brigham, indicates that socioeconomic and genetic factors likely interact in an additive way to affect people's risks of developing obesity and type 2 diabetes.

7 Mar 2023

New blood test examines biomarkers to help determine a person's risk for anxiety

Researchers from Indiana University School of Medicine have successfully developed a blood test for anxiety.

7 Mar 2023

FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver injury, according to a study led by investigators at the University of Alabama and Weill Cornell Medicine.

7 Mar 2023

Research shows the benefits of screening AML patients in remission for residual disease before bone marrow transplant

Researchers at the National Institutes of Health show the benefits of screening adult patients in remission from acute myeloid leukemia (AML) for residual disease before receiving a bone marrow transplant.

7 Mar 2023

Research helps explain the metabolic differences of people living at high altitudes

Compared to those of us who live at sea level, the 2 million people worldwide who live above 4,500 meters (or 14,764 feet) of elevation - about the height of Mount Rainier, Mount Whitney, and many Colorado and Alaska peaks - have lower rates of metabolic diseases such as diabetes, coronary artery disease, hypercholesterolemia, and obesity.

7 Mar 2023

Lack of sleep can be a major risk factor for cardiovascular disease

Scientific researchers have noticed a marked increase in heart attacks and strokes in the days following the change to daylight saving time each spring.

7 Mar 2023

Virtual care team strategy found to be safe and effective in improving treatment for heart failure patients

Recent studies have provided strong evidence that patients with heart failure can benefit from medical therapies that can reduce risk of worsening symptoms and extend patients' lives.

7 Mar 2023

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

7 Mar 2023

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

The drug denosumab is currently used to treat osteoporosis and bone metastases. For more than a decade, its potential therapeutic benefit in the treatment of breast cancer has also been studied.

7 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

The safety of short-course compared to long-course antibiotic therapy for ventilator-associated pneumonia

Researchers performed a meta-analysis of randomized controlled trials to evaluate the safety of short-course antibiotic treatment versus long-course antibiotic treatment for ventilator-associated pneumonia.

7 Mar 2023

Quality improvement initiative successfully reduced urine culture testing for asymptomatic bacteriuria and catheter-associated asymptomatic bacteriuria

Researchers reported on the execution of two electronic healthcare record interventions for reducing urine culture ordering in asymptomatic bacteriuria and catheter-associated ASB in a low-resource safety net system.

7 Mar 2023

Study: Women have higher risk of dying after coronary artery bypass surgery than men

Compared with men, women continue to have a roughly 30-40 percent higher risk of dying following coronary artery bypass surgery, according to a large study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center.

6 Mar 2023

Medicine News and Research

Discovery could lead to effective treatments for acute alcohol intoxication

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Poor sleep associated with different durations of compromised cardiovascular health

Newly diagnosed atrial fibrillation linked to modestly elevated risk of dementia

Reentry programs to help former prisoners obtain health care are often underused

Newly identified bone matrix protein may help treat osteosarcoma

Johns Hopkins researchers partner with NASA to send heart “tissue-on-a-chip” specimens into space

Additive effects of genetic, socioeconomic factors account for the prevalence of type 2 diabetes and obesity

New blood test examines biomarkers to help determine a person's risk for anxiety

FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

Research shows the benefits of screening AML patients in remission for residual disease before bone marrow transplant

Research helps explain the metabolic differences of people living at high altitudes

Lack of sleep can be a major risk factor for cardiovascular disease

Virtual care team strategy found to be safe and effective in improving treatment for heart failure patients

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

The safety of short-course compared to long-course antibiotic therapy for ventilator-associated pneumonia

Quality improvement initiative successfully reduced urine culture testing for asymptomatic bacteriuria and catheter-associated asymptomatic bacteriuria

Study: Women have higher risk of dying after coronary artery bypass surgery than men

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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