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Personalized scheduling of radiotherapy using genetic data could reduce side effects

A new clinical study led by the University of Leicester and conducted in the HOPE clinical trials facility at Leicester's Hospitals has revealed the pivotal role that changing the time of day that a patient receives radiotherapy could play in altering radiotherapy toxicity.

16 Nov 2018

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.

16 Nov 2018

Mechanisms that govern HIV latency differ in the gut and blood, finds study

Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published November 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, and colleagues.

16 Nov 2018

Drug used to treat dizziness may slow down growth of triple-negative breast cancer

Screening Food and Drug Administration approved compounds for their ability to stop cancer growth in the lab led to the finding that the drug flunarizine can slow down the growth of triple-negative breast cancer in an animal model of the disease.

16 Nov 2018

Nexus announces availability of Arsenic Trioxide Injection in the US

Nexus Pharmaceuticals announced today the immediate availability in the United States for Arsenic Trioxide Injection. Nexus Pharmaceuticals' Arsenic Trioxide Injection is available as 10 mg per 10 mL vial for injection.

16 Nov 2018

Person's sex hormones may play key role in trauma survival, finds study

A person's sex hormones may play a role in trauma survival, according to a Kansas State University researcher who has received a $650,000 grant from the U.S. Department of Defense.

16 Nov 2018

New approach allows pathogens to be starved by blocking important enzymes

More and more bacteria are resistant to available antibiotics. A team of chemists from the Technical University of Munich now presents a new approach: they have identified important enzymes in the metabolism of staphylococci. Blocking these enzymes in a targeted manner would allow the pathogens to be starved.

15 Nov 2018

New pharmacological agent shows promise for prevention of heart rhythm disorders

A new pharmacological agent demonstrates promising results for the prevention of a wide range of heart rhythm disorders, including both cardiac and brain injury-induced arrhythmias.

15 Nov 2018

Disrupting reproduction strategy of disease-causing parasites could help fight malaria

Malaria parasites know good times from bad and plan their offspring accordingly, scientists have found, in a development that could inform new treatments.

15 Nov 2018

Brain and muscle cells found within kidney organoids

Researchers have discovered the presence of rogue brain and muscle cells inside kidney organoids and used artificial intelligence to remove them.

15 Nov 2018

Researchers find no link between 'allergy friendly' dogs and lower risk of asthma

Growing up with dogs is linked to a lower risk of asthma, especially if the dogs are female, a new study from Karolinska Institutet and Uppsala University in Sweden shows. However, the researchers found no relation between 'allergy friendly' breeds and a lower risk of asthma. The study is published in the journal Scientific Reports.

15 Nov 2018

Scientists try to develop portable systems that can quickly produce biologics on demand

Many life-saving medicines, including insulin, antibodies and vaccines, are derived from living cells. These "biologics" can be difficult to obtain and store on the battlefield or in remote areas.

15 Nov 2018

Inhibition of prostaglandin E2 enhances ability to combat infectious colitis

The treatment of intestinal infections caused by some strains of the bacterium Escherichia coli, present in unsanitized or contaminated foods, may have a new ally.

15 Nov 2018

FDA warns against use of unapproved pain medications with implanted pumps

The U.S. Food and Drug Administration today alerted health care providers and patients about the serious complications that can occur when using medications not approved for use with implanted pumps that deliver medication into the spinal fluid to treat or manage pain.

15 Nov 2018

Researchers discover molecular basis for therapeutic actions of an African folk medicine

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for therapeutic actions of an African folk medicine used to treat a variety of illnesses and disorders including diabetes, pain, headaches, paralysis and epilepsy.

15 Nov 2018

New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis

The use of a new class of drugs in the treatment of type 2 diabetes, so called SGLT2 inhibitors, are linked to a twofold increased risk for lower-limb amputation as well as diabetic ketoacidosis, a serious diabetes complication.

14 Nov 2018

Research explores how exercise may help fight drug addiction

The siren call of addictive drugs can be hard to resist, and returning to the environment where drugs were previously taken can make resistance that much harder.

14 Nov 2018

TAMEST recognizes UT Southwestern’s Ralph DeBerardinis for changing our understanding of cancer

Ralph DeBerardinis, M.D., Ph.D., professor at the Children's Medical Center Research Institute at UT Southwestern is the recipient of the 2019 Edith and Peter O'Donnell Award in Medicine from TAMEST.

14 Nov 2018

Two genomic tests help identify most effective treatment for breast cancer patients

New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalized medicine ever nearer.

14 Nov 2018

Alcohol ads on social media sites with pro-drinking comments increase desire to drink

Alcohol advertisements on social media sites such as Facebook can increase young adults' desire to drink if the ads contain pro-drinking comments from users. That's according to new research in the current issue of the Journal of Studies on Alcohol and Drugs.

14 Nov 2018

Drugs News and Research

Personalized scheduling of radiotherapy using genetic data could reduce side effects

Gene editing could be used to halt kidney disease in patients with Joubert syndrome

Mechanisms that govern HIV latency differ in the gut and blood, finds study

Drug used to treat dizziness may slow down growth of triple-negative breast cancer

Nexus announces availability of Arsenic Trioxide Injection in the US

Person's sex hormones may play key role in trauma survival, finds study

New approach allows pathogens to be starved by blocking important enzymes

New pharmacological agent shows promise for prevention of heart rhythm disorders

Disrupting reproduction strategy of disease-causing parasites could help fight malaria

Brain and muscle cells found within kidney organoids

Researchers find no link between 'allergy friendly' dogs and lower risk of asthma

Scientists try to develop portable systems that can quickly produce biologics on demand

Inhibition of prostaglandin E2 enhances ability to combat infectious colitis

FDA warns against use of unapproved pain medications with implanted pumps

Researchers discover molecular basis for therapeutic actions of an African folk medicine

New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis

Research explores how exercise may help fight drug addiction

TAMEST recognizes UT Southwestern’s Ralph DeBerardinis for changing our understanding of cancer

Two genomic tests help identify most effective treatment for breast cancer patients

Alcohol ads on social media sites with pro-drinking comments increase desire to drink

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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